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Katarína Mikušová
Katarína Mikušová
Professor of Biochemistry, Comenius University in Bratislava, Faculty of Natural Sciences
Bestätigte E-Mail-Adresse bei uniba.sk
Titel
Zitiert von
Zitiert von
Jahr
Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis
V Makarov, G Manina, K Mikusova, U Möllmann, O Ryabova, ...
Science 324 (5928), 801-804, 2009
8352009
The embAB genes of Mycobacterium avium encode an arabinosyl transferase involved in cell wall arabinan biosynthesis that is the target for the antimycobacterial drug ethambutol.
AE Belanger, GS Besra, ME Ford, K Mikusová, JT Belisle, PJ Brennan, ...
Proceedings of the National Academy of Sciences 93 (21), 11919-11924, 1996
6621996
Biogenesis of the mycobacterial cell wall and the site of action of ethambutol
K Mikusova, RA Slayden, GS Besra, PJ Brennan
Antimicrobial agents and chemotherapy 39 (11), 2484-2489, 1995
4231995
Identification of a small molecule with activity against drug-resistant and persistent tuberculosis
F Wang, D Sambandan, R Halder, J Wang, SM Batt, B Weinrick, I Ahmad, ...
Proceedings of the National Academy of Sciences 110 (27), E2510-E2517, 2013
2482013
Decaprenylphosphoryl Arabinofuranose, the Donor of the d-Arabinofuranosyl Residues of Mycobacterial Arabinan, Is Formed via a Two-Step Epimerization of …
K Mikušová, H Huang, T Yagi, M Holsters, D Vereecke, W D'Haeze, ...
Journal of bacteriology 187 (23), 8020-8025, 2005
2402005
Definition of the first mannosylation step in phosphatidylinositol mannoside synthesis: PimA is essential for growth of mycobacteria
J Korduláková, M Gilleron, K Mikus̃ová, G Puzo, PJ Brennan, B Gicquel, ...
Journal of Biological Chemistry 277 (35), 31335-31344, 2002
2162002
Recognition of multiple effects of ethambutol on metabolism of mycobacterial cell envelope
L Deng, K Mikusová, KG Robuck, M Scherman, PJ Brennan, MR McNeil
Antimicrobial agents and chemotherapy 39 (3), 694-701, 1995
2091995
Benzothiazinones Are Suicide Inhibitors of Mycobacterial Decaprenylphosphoryl-β-d-ribofuranose 2′-Oxidase DprE1
C Trefzer, H Škovierová, S Buroni, A Bobovská, S Nenci, E Molteni, ...
Journal of the American Chemical Society 134 (2), 912-915, 2012
1992012
Synthesis of the Arabinose Donor. beta.-D-Arabinofuranosyl-1-monophosphoryldecaprenol, development of a basic arabinosyl-transferase assay, and identification of ethambutol as …
RE Lee, K Mikusova, PJ Brennan, GS Besra
Journal of the American Chemical Society 117 (48), 11829-11832, 1995
1941995
Biosynthesis of the Linkage Region of the Mycobacterial Cell Wall (∗)
K Mikusová, M Mikus, GS Besra, I Hancock, PJ Brennan
Journal of Biological Chemistry 271 (13), 7820-7828, 1996
1811996
Biosynthesis of the galactan component of the mycobacterial cell wall
K Mikušová, T Yagi, R Stern, MR McNeil, GS Besra, DC Crick, ...
Journal of Biological Chemistry 275 (43), 33890-33897, 2000
1562000
Molecular recognition and interfacial catalysis by the essential phosphatidylinositol mannosyltransferase PimA from mycobacteria
ME Guerin, J Kordulakova, F Schaeffer, Z Svetlikova, A Buschiazzo, ...
Journal of Biological Chemistry 282 (28), 20705-20714, 2007
1552007
DprE1 is a vulnerable tuberculosis drug target due to its cell wall localization
M Brecik, I Centárová, R Mukherjee, GS Kolly, S Huszár, A Bobovská, ...
ACS chemical biology 10 (7), 1631-1636, 2015
1432015
Truncated structural variants of lipoarabinomannan in ethambutol drug-resistant strains of Mycobacterium smegmatis: inhibition of arabinan biosynthesis by ethambutol
KH Khoo, E Douglas, P Azadi, JM Inamine, GS Besra, K Mikušová, ...
Journal of Biological Chemistry 271 (45), 28682-28690, 1996
1371996
Galactosyl transferases in mycobacterial cell wall synthesis
M Belánová, P Dianišková, PJ Brennan, GC Completo, NL Rose, ...
Journal of bacteriology 190 (3), 1141-1145, 2008
1312008
Interaction of Human Mannose-Binding Protein with Mycobacterium avium
VY Polotsky, JT Belisle, K Mikusova, RAB Ezekowitz, KA Joiner
Journal of Infectious Diseases 175 (5), 1159-1168, 1997
1201997
Identification of the required acyltransferase step in the biosynthesis of the phosphatidylinositol mannosides of Mycobacterium species
J Korduláková, M Gilleron, G Puzo, PJ Brennan, B Gicquel, K Mikusová, ...
Journal of Biological Chemistry 278 (38), 36285-36295, 2003
1132003
Development of 3, 5-dinitrobenzylsulfanyl-1, 3, 4-oxadiazoles and thiadiazoles as selective antitubercular agents active against replicating and nonreplicating Mycobacterium …
G Karabanovich, J Zemanová, T Smutný, R Székely, M Šarkan, ...
Journal of medicinal chemistry 59 (6), 2362-2380, 2016
1122016
The complex mechanism of antimycobacterial action of 5-fluorouracil
V Singh, M Brecik, R Mukherjee, JC Evans, Z Svetlíková, J Blaško, ...
Chemistry & biology 22 (1), 63-75, 2015
942015
Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance
G Manina, M Bellinzoni, MR Pasca, J Neres, A Milano, ...
Molecular microbiology 77 (5), 1172-1185, 2010
932010
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