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Richard C. Hartley
Richard C. Hartley
Verified email at glasgow.ac.uk - Homepage
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Year
Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS
ET Chouchani, VR Pell, E Gaude, D Aksentijević, SY Sundier, EL Robb, ...
Nature 515 (7527), 431-435, 2014
24112014
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
EL Mills, DG Ryan, HA Prag, D Dikovskaya, D Menon, Z Zaslona, ...
Nature 556 (7699), 113-117, 2018
12582018
Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I
ET Chouchani, C Methner, SM Nadtochiy, A Logan, VR Pell, S Ding, ...
Nature medicine 19 (6), 753-759, 2013
6382013
Mitochondria as a therapeutic target for common pathologies
MP Murphy, RC Hartley
Nature Reviews Drug Discovery 17 (12), 865-886, 2018
5972018
Mitochondrial pharmacology
RAJ Smith, RC Hartley, HM Cocheme, MP Murphy
Trends in pharmacological sciences 33 (6), 341-352, 2012
5372012
Mitochondria-targeted small molecule therapeutics and probes
RAJ Smith, RC Hartley, MP Murphy
Antioxidants & redox signaling 15 (12), 3021-3038, 2011
4212011
Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrix
HM Cochemé, C Quin, SJ McQuaker, F Cabreiro, A Logan, TA Prime, ...
Cell metabolism 13 (3), 340-350, 2011
3192011
Are carotenoids a red herring in sexual display?
RC Hartley, MW Kennedy
Trends in Ecology & Evolution 19 (7), 353-354, 2004
2522004
Kinetic and stoichiometric assessment of the antioxidant activity of flavonoids by electron spin resonance spectroscopy
DB McPhail, RC Hartley, PT Gardner, GG Duthie
Journal of agricultural and food chemistry 51 (6), 1684-1690, 2003
1732003
Determination of Flavonol Metabolites in Plasma and Tissues of Rats by HPLC−Radiocounting and Tandem Mass Spectrometry Following Oral Ingestion of [2-14C …
W Mullen, BA Graf, ST Caldwell, RC Hartley, GG Duthie, CA Edwards, ...
Journal of agricultural and food chemistry 50 (23), 6902-6909, 2002
1632002
Reactive oxygen species induce virus-independent MAVS oligomerization in systemic lupus erythematosus
IA Buskiewicz, T Montgomery, EC Yasewicz, SA Huber, MP Murphy, ...
Science signaling 9 (456), ra115-ra115, 2016
1622016
Bioavailability of [2-14C]Quercetin-4′-glucoside in Rats
W Mullen, JM Rouanet, C Auger, PL Teissedre, ST Caldwell, RC Hartley, ...
Journal of agricultural and food chemistry 56 (24), 12127-12137, 2008
1512008
Potential therapeutic antioxidants that combine the radical scavenging ability of myricetin and the lipophilic chain of vitamin E to effectively inhibit microsomal lipid …
CJ Bennett, ST Caldwell, DB McPhail, PC Morrice, GG Duthie, RC Hartley
Bioorganic & medicinal chemistry 12 (9), 2079-2098, 2004
1512004
Selective uncoupling of individual mitochondria within a cell using a mitochondria-targeted photoactivated protonophore
S Chalmers, ST Caldwell, C Quin, TA Prime, AM James, AG Cairns, ...
Journal of the American Chemical Society 134 (2), 758-761, 2012
1302012
Using the mitochondria-targeted ratiometric mass spectrometry probe MitoB to measure H2O2 in living Drosophila
HM Cochemé, A Logan, TA Prime, I Abakumova, C Quin, SJ McQuaker, ...
Nature protocols 7 (5), 946-958, 2012
1292012
Selective superoxide generation within mitochondria by the targeted redox cycler MitoParaquat
EL Robb, JM Gawel, D Aksentijević, HM Cochemé, TS Stewart, ...
Free Radical Biology and Medicine 89, 883-894, 2015
1272015
Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation
DJ Fazakerley, AY Minard, JR Krycer, KC Thomas, J Stöckli, DJ Harney, ...
Journal of Biological Chemistry 293 (19), 7315-7328, 2018
1262018
Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation
JL Martin, ASH Costa, AV Gruszczyk, TE Beach, FM Allen, HA Prag, ...
Nature metabolism 1 (10), 966-974, 2019
1182019
Individuals with higher metabolic rates have lower levels of reactive oxygen species in vivo
K Salin, SK Auer, AM Rudolf, GJ Anderson, AG Cairns, W Mullen, ...
Biology Letters 11 (9), 20150538, 2015
1172015
In vivo levels of mitochondrial hydrogen peroxide increase with age in mtDNA mutator mice
A Logan, IG Shabalina, TA Prime, S Rogatti, AV Kalinovich, RC Hartley, ...
Aging Cell 13 (4), 765-768, 2014
1082014
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