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Praveen Shukla, MS PharmD PhD
Praveen Shukla, MS PharmD PhD
Associate Director, Translational Medicine, Vertex Pharmaceuticals
Bestätigte E-Mail-Adresse bei vrtx.com - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Chemically defined generation of human cardiomyocytes
PW Burridge, E Matsa, P Shukla, ZC Lin, JM Churko, AD Ebert, F Lan, ...
Nature methods 11 (8), 855-860, 2014
16102014
High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells
A Sharma, PW Burridge, WL McKeithan, R Serrano, P Shukla, N Sayed, ...
Science translational medicine 9 (377), eaaf2584, 2017
3492017
Development of a scalable suspension culture for cardiac differentiation from human pluripotent stem cells
VC Chen, J Ye, P Shukla, G Hua, D Chen, Z Lin, J Liu, J Chai, J Gold, ...
Stem cell research 15 (2), 365-375, 2015
1802015
iPSC-derived cardiomyocytes reveal abnormal TGF-β signalling in left ventricular non-compaction cardiomyopathy
K Kodo, SG Ong, F Jahanbani, V Termglinchan, K Hirono, ...
Nature cell biology 18 (10), 1031-1042, 2016
1792016
Transcriptome profiling of patient-specific human iPSC-cardiomyocytes predicts individual drug safety and efficacy responses in vitro
E Matsa, PW Burridge, KH Yu, JH Ahrens, V Termglinchan, H Wu, C Liu, ...
Cell stem cell 19 (3), 311-325, 2016
1682016
Engineered heart tissues and induced pluripotent stem cells: macro-and microstructures for disease modeling, drug screening, and translational studies
E Tzatzalos, OJ Abilez, P Shukla, JC Wu
Advanced drug delivery reviews 96, 234-244, 2016
1582016
Paracrine effects of the pluripotent stem cell-derived cardiac myocytes salvage the injured myocardium
A Tachibana, MR Santoso, M Mahmoudi, P Shukla, L Wang, M Bennett, ...
Circulation research 121 (6), e22-e36, 2017
1462017
Passive stretch induces structural and functional maturation of engineered heart muscle as predicted by computational modeling
OJ Abilez, E Tzatzalos, H Yang, MT Zhao, G Jung, AM Zöllner, M Tiburcy, ...
Stem cells 36 (2), 265-277, 2018
1442018
Exosomes from induced pluripotent stem cell–derived cardiomyocytes promote autophagy for myocardial repair
MR Santoso, G Ikeda, Y Tada, JH Jung, E Vaskova, RG Sierra, C Gati, ...
Journal of the American Heart Association 9 (6), e014345, 2020
832020
Curcumin ((E, E)-1, 7-bis (4-hydroxy-3-methoxyphenyl)-1, 6-heptadiene-3, 5-dione) activates and desensitizes the nociceptor ion channel TRPA1
AW Leamy, P Shukla, MA McAlexander, MJ Carr, S Ghatta
Neuroscience letters 503 (3), 157-162, 2011
822011
MT2 receptors mediate the inhibitory effects of melatonin on nitric oxide-induced relaxation of porcine isolated coronary arteries
RR Tunstall, P Shukla, A Grazul-Bilska, C Sun, ST O'Rourke
Journal of pharmacology and experimental therapeutics 336 (1), 127-133, 2011
682011
Comparison of non-coding RNAs in exosomes and functional efficacy of human embryonic stem cell-versus induced pluripotent stem cell-derived cardiomyocytes
WH Lee, WY Chen, NY Shao, D Xiao, X Qin, N Baker, HR Bae, TT Wei, ...
Stem Cells 35 (10), 2138-2149, 2017
632017
Comparison of non-human primate versus human induced pluripotent stem cell-derived cardiomyocytes for treatment of myocardial infarction
X Zhao, H Chen, D Xiao, H Yang, I Itzhaki, X Qin, T Chour, A Aguirre, ...
Stem cell reports 10 (2), 422-435, 2018
602018
GLP-1 receptor agonist liraglutide reverses long-term atypical antipsychotic treatment associated behavioral depression and metabolic abnormalities in rats
AN Sharma, SS Ligade, JN Sharma, P Shukla, KM Elased, JB Lucot
Metabolic brain disease 30, 519-527, 2015
602015
2011 AND 2012 EARLY CAREERS ACHIEVEMENT AWARDS: Placental programming: How the maternal environment can impact placental function,
KA Vonnahme, CO Lemley, P Shukla, ST O'Rourke
Journal of animal science 91 (6), 2467-2480, 2013
472013
Glucagon-like peptide-1 (GLP-1) receptor agonist prevents development of tolerance to anti-anxiety effect of ethanol and withdrawal-induced anxiety in rats
AN Sharma, A Pise, JN Sharma, P Shukla
Metabolic brain disease 30, 719-730, 2015
352015
Assessment of a model-informed precision dosing platform use in routine clinical care for personalized busulfan therapy in the pediatric hematopoietic cell transplantation (HCT …
P Shukla, S Goswami, RJ Keizer, BA Winger, S Kharbanda, CC Dvorak, ...
Frontiers in Pharmacology 11, 888, 2020
312020
Melatonin Inhibits Nitric Oxide Signaling by Increasing PDE5 Phosphorylation in Coronary Arteries
P Shukla, C Sun, ST O'Rourke
American Journal of Physiology-Heart and Circulatory Physiology 303, H1418 …, 2012
252012
Maternal nutrient restriction during pregnancy impairs an endothelium-derived hyperpolarizing factor-like pathway in sheep fetal coronary arteries
P Shukla, S Ghatta, N Dubey, CO Lemley, ML Johnson, A Modgil, ...
American Journal of Physiology-Heart and Circulatory Physiology 307 (2 …, 2014
242014
Effect of maternal nutrient restriction and melatonin supplementation from mid to late gestation on vascular reactivity of maternal and fetal placental arteries
P Shukla, CO Lemley, N Dubey, AM Meyer, ST O'Rourke, KA Vonnahme
Placenta 35 (7), 461-466, 2014
242014
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