James Allison
James Allison
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TitelZitiert vonJahr
Restoring function in exhausted CD8 T cells during chronic viral infection
DL Barber, EJ Wherry, D Masopust, B Zhu, JP Allison, AH Sharpe, ...
Nature 439 (7077), 682, 2006
Enhancement of antitumor immunity by CTLA-4 blockade
DR Leach, MF Krummel, JP Allison
Science 271 (5256), 1734-1736, 1996
CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones
FA Harding, JG McArthur, JA Gross, DH Raulet, JP Allison
Nature 356 (6370), 607, 1992
CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation.
MF Krummel, JP Allison
Journal of Experimental Medicine 182 (2), 459-465, 1995
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
GQ Phan, JC Yang, RM Sherry, P Hwu, SL Topalian, ...
Proceedings of the National Academy of Sciences 100 (14), 8372-8377, 2003
The future of immune checkpoint therapy
P Sharma, JP Allison
Science 348 (6230), 56-61, 2015
Tumor rejection after direct costimulation of CD8+ T cells by B7-transfected melanoma cells
SE Townsend, JP Allison
Science 259 (5093), 368-370, 1993
Immunologic correlates of the abscopal effect in a patient with melanoma
MA Postow, MK Callahan, CA Barker, Y Yamada, J Yuan, S Kitano, Z Mu, ...
New England Journal of Medicine 366 (10), 925-931, 2012
Synergism of cytotoxic T lymphocyte–associated antigen 4 blockade and depletion of CD25+ regulatory T cells in antitumor therapy reveals alternative pathways for suppression of …
RPM Sutmuller, LM Van Duivenvoorde, A Van Elsas, TNM Schumacher, ...
Journal of Experimental Medicine 194 (6), 823-832, 2001
PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors
MA Curran, W Montalvo, H Yagita, JP Allison
Proceedings of the National Academy of Sciences 107 (9), 4275-4280, 2010
The prioritization of cancer antigens: a national cancer institute pilot project for the acceleration of translational research
MA Cheever, JP Allison, AS Ferris, OJ Finn, BM Hastings, TT Hecht, ...
Clinical cancer research 15 (17), 5323-5337, 2009
Combination immunotherapy of B16 melanoma using anti–cytotoxic T lymphocyte–associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF …
A Van Elsas, AA Hurwitz, JP Allison
Journal of Experimental Medicine 190 (3), 355-366, 1999
ICOS co-stimulatory receptor is essential for T-cell activation and function
C Dong, AE Juedes, UA Temann, S Shresta, JP Allison, NH Ruddle, ...
Nature 409 (6816), 97, 2001
Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
FS Hodi, MC Mihm, RJ Soiffer, FG Haluska, M Butler, MV Seiden, T Davis, ...
Proceedings of the National Academy of Sciences 100 (8), 4712-4717, 2003
Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens
MM Gubin, X Zhang, H Schuster, E Caron, JP Ward, T Noguchi, Y Ivanova, ...
Nature 515 (7528), 577, 2014
CTLA-4-MEDIATED INHIBITION IN REGULATION OF T CELL RESPONSES: Mechanisms and Manipulation in Tumor Immunotherapy
CA Chambers, MS Kuhns, JG Egen, JP Allison
Annual review of immunology 19 (1), 565-594, 2001
CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells.
MF Krummel, JP Allison
Journal of Experimental Medicine 183 (6), 2533-2540, 1996
Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival
BC Özdemir, T Pentcheva-Hoang, JL Carstens, X Zheng, CC Wu, ...
Cancer cell 25 (6), 719-734, 2014
Immune checkpoint targeting in cancer therapy: toward combination strategies with curative potential
P Sharma, JP Allison
Cell 161 (2), 205-214, 2015
CTLA-4: new insights into its biological function and use in tumor immunotherapy
JG Egen, MS Kuhns, JP Allison
Nature immunology 3 (7), 611, 2002
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