Regulation of bifurcating B cell trajectories by mutual antagonism between transcription factors IRF4 and IRF8 H Xu, VK Chaudhri, Z Wu, K Biliouris, K Dienger-Stambaugh, Y Rochman, ... Nature immunology 16 (12), 1274-1281, 2015 | 133 | 2015 |
Bacterial sugar utilization gives rise to distinct single‐cell behaviours T Afroz*, K Biliouris*, Y Kaznessis, CL Beisel, (* co-first authors) Molecular microbiology 93 (6), 1093-1103, 2014 | 72 | 2014 |
Stochastic simulations of a synthetic bacteria-yeast ecosystem K Biliouris, D Babson, C Schmidt-Dannert, YN Kaznessis BMC systems biology 6, 1-14, 2012 | 39 | 2012 |
Systems pharmacology to predict drug safety in drug development MN Trame, K Biliouris, LJ Lesko, JT Mettetal European Journal of Pharmaceutical Sciences 94, 93-95, 2016 | 35 | 2016 |
Stochastic simulations of the tetracycline operon K Biliouris, P Daoutidis, YN Kaznessis BMC systems biology 5, 1-19, 2011 | 28 | 2011 |
proTeOn and proTeOff, new protein devices that inducibly activate bacterial gene expression K Volzing, K Biliouris, YN Kaznessis ACS Chemical Biology 6 (10), 1107-1116, 2011 | 26 | 2011 |
A semi‐mechanistic population pharmacokinetic model of nusinersen: an antisense oligonucleotide for the treatment of spinal muscular atrophy K Biliouris, P Gaitonde, W Yin, DA Norris, Y Wang, S Henry, R Fey, ... CPT: Pharmacometrics & Systems Pharmacology 7 (9), 581-592, 2018 | 23 | 2018 |
A study of novel exploratory tools, digital technologies, and central nervous system biomarkers to characterize unipolar depression O Sverdlov, J Curcic, K Hannesdottir, L Gou, V De Luca, F Ambrosetti, ... Frontiers in psychiatry 12, 640741, 2021 | 21 | 2021 |
Quantitative systems pharmacology model to predict the effects of commonly used anticoagulants on the human coagulation network S Hartmann, K Biliouris, LJ Lesko, U Nowak‐Göttl, MN Trame CPT: Pharmacometrics & Systems Pharmacology 5 (10), 554-564, 2016 | 17 | 2016 |
Trade-offs in engineering sugar utilization pathways for titratable control T Afroz, K Biliouris, KE Boykin, Y Kaznessis, CL Beisel ACS synthetic biology 4 (2), 141-149, 2015 | 16 | 2015 |
Quantitative systems pharmacology model-based predictions of clinical endpoints to optimize Warfarin and Rivaroxaban anti-thrombosis therapy S Hartmann, K Biliouris, LJ Lesko, U Nowak-Göttl, MN Trame Frontiers in Pharmacology 11, 520954, 2020 | 13 | 2020 |
Perspective on the state of pharmacometrics and systems pharmacology integration MN Trame, M Riggs, K Biliouris, D Marathe, J Mettetal, TM Post, ML Rizk, ... CPT: pharmacometrics & systems pharmacology 7 (10), 617-620, 2018 | 13 | 2018 |
A pre-clinical quantitative model predicts the pharmacokinetics/pharmacodynamics of an anti-BDCA2 monoclonal antibody in humans K Biliouris, I Nestorov, H Naik, D Dai, G Xiao, Q Wang, A Pellerin, ... Journal of pharmacokinetics and pharmacodynamics 45, 817-827, 2018 | 12 | 2018 |
Synthetic Biology, 2 Volumes RA Meyers John Wiley & Sons, 2015 | 12 | 2015 |
MatVPC: a user‐friendly MATLAB‐based tool for the simulation and evaluation of systems pharmacology models K Biliouris, M Lavielle, MN Trame CPT: Pharmacometrics & Systems Pharmacology 4 (9), 547-557, 2015 | 11 | 2015 |
A clinical population pharmacokinetic/pharmacodynamic model for BIIB059, a monoclonal antibody for the treatment of systemic and cutaneous lupus erythematosus S Hartmann, K Biliouris, H Naik, D Rabah, L Stevenson, C Shen, ... Journal of Pharmacokinetics and Pharmacodynamics 47, 255-266, 2020 | 8 | 2020 |
Trade-offs in engineering sugar utilization pathways for titratable control. ACS Synth Biol 4: 141–149 T Afroz, K Biliouris, KE Boykin, Y Kaznessis, CL Beisel | 2 | 2015 |
A study of new exploratory tools, digital technologies and biomarkers to characterize depression A Sverdlov, J Curcic, K Hannesdottir, V De Luca, F Ambrosetti, B Zhang, ... Frontiers in psychiatry 12, 2021 | 1 | 2021 |
DEVELOPMENT OF A SYSTEMS PHARMACOLOGY MODEL TO PREDICT THE EFFECTS OF WARFARIN AND RIVAROXABAN ON THE HUMAN COAGULATION NETWORK. S Hartmann, K Biliouris, LJ Lesko, U Nowak-Goettl, MN Trame CLINICAL PHARMACOLOGY & THERAPEUTICS 99, S74-S74, 2016 | 1 | 2016 |
Integrated data mining and systems pharmacology to explore the comparative safety of brand-name and generic drugs L Bilious, MN Trame, S Schmidt, L Fang, LJ Lesko Annual Meeting of the American College of Clinical Pharmacology, San …, 2015 | 1 | 2015 |