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Eric WFW Alton
Eric WFW Alton
Professor of Gene Therapy and Respiratory Medicine
Verified email at imperial.ac.uk - Homepage
Title
Cited by
Cited by
Year
Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis
NJ Caplen, EWFW Alton, PG Mddleton, JR Dorin, BJ Stevenson, X Gao, ...
Nature medicine 1 (1), 39-46, 1995
9751995
Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis
NJ Caplen, EWFW Alton, PG Mddleton, JR Dorin, BJ Stevenson, X Gao, ...
Nature medicine 1 (1), 39-46, 1995
9751995
Cationic lipid-mediated CFTR gene transfer to the lungs and nose of patients with cystic fibrosis: a double-blind placebo-controlled trial
E Alton, M Stern, R Farley, A Jaffe, SL Chadwick, J Phillips, J Davies, ...
The Lancet 353 (9157), 947-954, 1999
5631999
Non–invasive liposome–mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice
E Alton, PG Middleton, NJ Caplen, SN Smith, DM Steel, FM Munkonge, ...
Nature genetics 5 (2), 135-142, 1993
5361993
Non–invasive liposome–mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice
E Alton, PG Middleton, NJ Caplen, SN Smith, DM Steel, FM Munkonge, ...
Nature genetics 5 (2), 135-142, 1993
5361993
Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial
EWFW Alton, DK Armstrong, D Ashby, KJ Bayfield, D Bilton, ...
The Lancet Respiratory Medicine 3 (9), 684-691, 2015
5032015
Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial
EWFW Alton, DK Armstrong, D Ashby, KJ Bayfield, D Bilton, ...
The Lancet Respiratory Medicine 3 (9), 684-691, 2015
5032015
Cystic fibrosis in the mouse by targeted insertional mutagenesis
JR Dorin, P Dickinson, EWFW Alton, SN Smith, DM Geddes, ...
Nature 359 (6392), 211-215, 1992
3851992
CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression
SC Hyde, IA Pringle, S Abdullah, AE Lawton, LA Davies, A Varathalingam, ...
Nature biotechnology 26 (5), 549-551, 2008
3712008
Efficient gene transfer to airway epithelium using recombinant Sendai virus
Y Yonemitsu, C Kitson, S Ferrari, R Farley, U Griesenbach, D Judd, ...
Nature biotechnology 18 (9), 970-973, 2000
2912000
Lung clearance index is a sensitive, repeatable and practical measure of airways disease in adults with cystic fibrosis
AR Horsley, PM Gustafsson, KA Macleod, C Saunders, AP Greening, ...
Thorax 63 (2), 135-140, 2008
2792008
In vitro liposome-mediated DNA transfection of epithelial cell lines using the cationic liposome DC-Chol/DOPE.
NJ Caplen, E Kinrade, F Sorgi, X Gao, D Gruenert, D Geddes, C Coutelle, ...
Gene Therapy 2 (9), 603-613, 1995
2301995
Barriers to and new approaches for gene therapy and gene delivery in cystic fibrosis
S Ferrari, DM Geddes, EWFW Alton
Advanced drug delivery reviews 54 (11), 1373-1393, 2002
2222002
Increased airway smooth muscle mass in children with asthma, cystic fibrosis, and non-cystic fibrosis bronchiectasis
N Regamey, M Ochs, TN Hilliard, C Mühlfeld, N Cornish, L Fleming, ...
American journal of respiratory and critical care medicine 177 (8), 837-843, 2008
1952008
Protocols for in vivo measurement of the ion transport defects in cystic fibrosis nasal epithelium
PG Middleton, DM Geddes, EW Alton
European Respiratory Journal 7 (11), 2050-2056, 1994
1891994
Gene transfer to the lung: lessons learned from more than 2 decades of CF gene therapy
U Griesenbach, EWFW Alton, ...
Advanced drug delivery reviews 61 (2), 128-139, 2009
1832009
A demonstration using mouse models that successful gene therapy for cystic fibrosis requires only partial gene correction.
JR Dorin, R Farley, S Webb, SN Smith, E Farini, SJ Delaney, ...
Gene therapy 3 (9), 797-801, 1996
1781996
Magnetic nanoparticles as gene delivery agents: enhanced transfection in the presence of oscillating magnet arrays
SC McBain, U Griesenbach, S Xenariou, A Keramane, CD Batich, E Alton, ...
Nanotechnology 19 (40), 405102, 2008
1682008
Cystic fibrosis mice carrying the missense mutation G551D replicate human genotype‐phenotype correlations.
SJ Delaney, EW Alton, SN Smith, DP Lunn, R Farley, PK Lovelock, ...
The EMBO journal 15 (5), 955-963, 1996
1681996
The extra-and intracellular barriers to lipid and adenovirus-mediated pulmonary gene transfer in native sheep airway epithelium
C Kitson, B Angel, D Judd, S Rothery, NJ Severs, A Dewar, L Huang, ...
Gene therapy 6 (4), 534-546, 1999
1671999
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