Lutz Weber
Lutz Weber
Morphochem Roche Leipzig Budapest OntoChem NexusPharma ETH OntoChem IT Solutions
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Titel
Zitiert von
Zitiert von
Jahr
Discovery of new multi component reactions with combinatorial methods
L Weber, K Illgen, M Almstetter
Synlett 1999 (03), 366-374, 1999
4891999
Multi-component reactions and evolutionary chemistry
L Weber
Drug Discovery Today 7, 143-147, 2002
4702002
The application of multi-component reactions in drug discovery
L Weber
Current Medicinal Chemistry 9 (23), 2085-2093, 2002
4482002
Multicomponent reactions in organic synthesis
J Zhu, Q Wang, M Wang
John Wiley & Sons, 2014
2932014
Synthesis of Imidazo[1, 2-a] annulated Pyridines, Pyrazines and Pyrimidines by a Novel Three Component Condensation
K Groebke, L Weber, E Mehlin
Synlett 661, 3635-3638, 1998
2891998
Optimization of the biological activity of combinatorial compound libraries by a genetic algorithm
L Weber, S Wallbaum, C Broger, K Gubernator
Angewandte Chemie International Edition in English 34 (20), 2280-2282, 1995
2561995
Molecular basis for the inhibition of p53 by Mdmx
GM Popowicz, A Czarna, U Rothweiler, A Szwagierczak, M Krajewski, ...
Cell cycle 6 (19), 2386-2392, 2007
1512007
The CHEMDNER corpus of chemicals and drugs and its annotation principles
M Krallinger, O Rabal, F Leitner, M Vazquez, D Salgado, Z Lu, R Leaman, ...
Journal of cheminformatics 7 (1), 1-17, 2015
1422015
High-diversity combinatorial libraries
L Weber
Current opinion in chemical biology 4 (3), 295-302, 2000
1262000
Combinatorial docking and combinatorial chemistry: design of potent non-peptide thrombin inhibitors
HJ Böhm, DW Banner, L Weber
Journal of computer-aided molecular design 13 (1), 51-56, 1999
1221999
Photocatalytic oxygenation of hydrocarbons with (tetraarylporphyrinato) iron (III) complexes and molecular oxygen. Comparison with microsomal cytochrome P-450 mediated …
L Weber, R Hommel, J Behling, G Haufe, H Hennig
Journal of the American Chemical Society 116 (6), 2400-2408, 1994
1151994
Molecular recognition at the thrombin active site: structure-based design and synthesis of potent and selective thrombin inhibitors and the X-ray crystal structures of two …
U Obst, DW Banner, L Weber, F Diederich
Chemistry & biology 4 (4), 287-295, 1997
1131997
Production of sophorose lipid by Candida (Torulopsis) apicola grown on glucose
RK Hommel, L Weber, A Weiss, U Himmelreich, O Rilke, HP Kleber
Journal of biotechnology 33 (2), 147-155, 1994
1041994
Synthesis of novel nonpeptidic thrombin inhibitors
U Obst, P Betschmann, C Lerner, P Seiler, F Diederich, V Gramlich, ...
Helvetica Chimica Acta 83 (5), 855-909, 2000
952000
Evolutionary combinatorial chemistry: application of genetic algorithms
L Weber
Drug Discovery Today 3 (8), 379-385, 1998
911998
Isoquinolin‐1‐one Inhibitors of the MDM2–p53 Interaction
U Rothweiler, A Czarna, M Krajewski, J Ciombor, C Kalinski, V Khazak, ...
ChemMedChem 3 (7), 1118-1128, 2008
782008
On the industrial applications of MCRs: Molecular diversity in drug discovery and generic drug synthesis
C Kalinski, M Umkehrer, L Weber, J Kolb, C Burdack, G Ross
Molecular diversity 14 (3), 513-522, 2010
692010
Design of Novel, Nonpeptidic Thrombin Inhibitors and Structure of a Thrombin–Inhibitor Complex
U Obst, V Gramlich, F Diederich, L Weber, DW Banner
Angewandte Chemie International Edition in English 34 (16), 1739-1742, 1995
671995
Mdm2 and MdmX inhibitors for the treatment of cancer: a patent review (2011–present)
K Zak, A Pecak, B Rys, B Wladyka, A Doemling, L Weber, TA Holak, ...
Expert opinion on therapeutic patents 23 (4), 425-448, 2013
662013
Tubulysin conjugates
A Dömling, L Weber
US Patent 7,776,814, 2010
662010
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