Prof. Tyson V. Sharp
Prof. Tyson V. Sharp
Barts Cancer Institute, Queen Mary University of London
Bestätigte E-Mail-Adresse bei - Startseite
Zitiert von
Zitiert von
K15 protein of Kaposi’s sarcoma-associated herpesvirus is latently expressed and binds to HAX-1, a protein with antiapoptotic function
TV Sharp, HW Wang, A Koumi, D Hollyman, Y Endo, H Ye, MQ Du, ...
Journal of virology 76 (2), 802-816, 2002
Comparative analysis of the regulation of the interferoninducible protein kinase PKR by Epstein-Barr virus RNAs EBER-1 and EBER-2 and adenovirus VA, RNA
TV Sharp, M Schwemmle, I Jeffrey, K Laing, H Mellor, CG Proud, K Hilse, ...
Nucleic acids research 21 (19), 4483-4490, 1993
Characterization of an anti‐apoptotic glycoprotein encoded by Kaposi's sarcoma‐associated herpesvirus which resembles a spliced variant of human survivin
HW Wang, TV Sharp, A Koumi, G Koentges, C Boshoff
The EMBO journal 21 (11), 2602-2615, 2002
The vaccinia virus E3L gene product interacts with both the regulatory and the substrate binding regions of PKR: implications for PKR autoregulation
TV Sharp, F Moonan, A Romashko, B Joshi, GN Barber, R Jagus
Virology 250 (2), 302-315, 1998
Regulation of the interferon-inducible eIF-2α protein kinase by small RNAs
MJ Clemens, KG Laing, IW Jeffrey, A Schofield, TV Sharp, A Elia, V Matys, ...
Biochimie 76 (8), 770-778, 1994
LIM domains-containing protein 1 (LIMD1), a tumor suppressor encoded at chromosome 3p21. 3, binds pRB and represses E2F-driven transcription
TV Sharp, F Munoz, D Bourboulia, N Presneau, E Darai, HW Wang, ...
Proceedings of the National Academy of Sciences 101 (47), 16531-16536, 2004
The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity
DE Foxler, KS Bridge, V James, TM Webb, M Mee, SCK Wong, Y Feng, ...
Nature cell biology 14 (2), 201-208, 2012
The M type K15 protein of Kaposi's sarcoma-associated herpesvirus regulates microRNA expression via its SH2-binding motif to induce cell migration and invasion
YH Tsai, MF Wu, YH Wu, SJ Chang, SF Lin, TV Sharp, HW Wang
Journal of virology 83 (2), 622-632, 2009
The La antigen inhibits the activation of the interferoninducible protein kinase PKR by sequestering and unwinding double-stranded RNA
Q Xao, TV Sharp, IW Jeffrey, MC James, GJM Pruijn, WJ Venrooij, ...
Nucleic acids research 22 (13), 2512-2518, 1994
SMG-1 and mTORC1 act antagonistically to regulate response to injury and growth in planarians
C Gonzalez-Estevez, DA Felix, MD Smith, J Paps, SJ Morley, V James, ...
PLoS Genet 8 (3), e1002619, 2012
The chromosome 3p21. 3-encoded gene, LIMD1, is a critical tumor suppressor involved in human lung cancer development
TV Sharp, A Al-Attar, DE Foxler, L Ding, QA Thomas, Y Zhang, HS Nijmeh, ...
Proceedings of the National Academy of Sciences 105 (50), 19932-19937, 2008
MicroRNA-155 induction via TNF-α and IFN-γ suppresses expression of programmed death ligand-1 (PD-L1) in human primary cells
D Yee, KM Shah, MC Coles, TV Sharp, D Lagos
Journal of Biological Chemistry 292 (50), 20683-20693, 2017
Homologous Regions of the α Subunit of Eukaryotic Translational Initiation Factor 2 (eIF2α) and the Vaccinia Virus K3L Gene Product Interact with the Same Domain within the …
TV Sharp, JE Witzel, R Jagus
European journal of biochemistry 250 (1), 85-91, 1997
LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencing
V James, Y Zhang, DE Foxler, CH De Moor, YW Kong, TM Webb, TJ Self, ...
Proceedings of the National Academy of Sciences 107 (28), 12499-12504, 2010
The role of hypoxia in stem cell potency and differentiation
KE Hawkins, TV Sharp, TR McKay
Regenerative medicine 8 (6), 771-782, 2013
Activation of the interferon-inducible (2′-5′) oligoadenylate synthetase by the Epstein–Barr virus RNA, EBER-1
TV Sharp, DA Raine, DR Gewert, B Joshi, R Jagus, MJ Clemens
Virology 257 (2), 303-313, 1999
Gene expression array profile of human osteosarcoma
P Leonard, T Sharp, S Henderson, D Hewitt, J Pringle, A Sandison, ...
British journal of cancer 89 (12), 2284-2288, 2003
Reversal of the double‐stranded‐RNA‐induced inhibition of protein synthesis by a catalytically inactive mutant of the protein kinase PKR
European journal of biochemistry 214 (3), 945-948, 1993
Functional expression of secreted proteins from a bicistronic retroviral cassette based on foot-and-mouth disease virus 2A can be position dependent
DG Rothwell, R Crossley, JS Bridgeman, V Sheard, Y Zhang, TV Sharp, ...
Human gene therapy 21 (11), 1631-1637, 2010
The hypoxic tumor microenvironment: driving the tumorigenesis of non-small-cell lung cancer
JG Foster, SCK Wong, TV Sharp
Future Oncology 10 (16), 2659-2674, 2014
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