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Prof. Tyson V. Sharp
Prof. Tyson V. Sharp
Barts Cancer Institute, Queen Mary University of London
Bestätigte E-Mail-Adresse bei qmul.ac.uk - Startseite
Titel
Zitiert von
Zitiert von
Jahr
K15 protein of Kaposi’s sarcoma-associated herpesvirus is latently expressed and binds to HAX-1, a protein with antiapoptotic function
TV Sharp, HW Wang, A Koumi, D Hollyman, Y Endo, H Ye, MQ Du, ...
Journal of virology 76 (2), 802-816, 2002
2472002
Comparative analysis of the regulation of the interferoninducible protein kinase PKR by Epstein-Barr virus RNAs EBER-1 and EBER-2 and adenovirus VA, RNA
TV Sharp, M Schwemmle, I Jeffrey, K Laing, H Mellor, CG Proud, K Hilse, ...
Nucleic acids research 21 (19), 4483-4490, 1993
2471993
Characterization of an anti‐apoptotic glycoprotein encoded by Kaposi's sarcoma‐associated herpesvirus which resembles a spliced variant of human survivin
HW Wang, TV Sharp, A Koumi, G Koentges, C Boshoff
The EMBO journal, 2002
2242002
The vaccinia virus E3L gene product interacts with both the regulatory and the substrate binding regions of PKR: implications for PKR autoregulation
TV Sharp, F Moonan, A Romashko, B Joshi, GN Barber, R Jagus
Virology 250 (2), 302-315, 1998
1681998
MicroRNA-155 induction via TNF-α and IFN-γ suppresses expression of programmed death ligand-1 (PD-L1) in human primary cells
D Yee, KM Shah, MC Coles, TV Sharp, D Lagos
Journal of Biological Chemistry 292 (50), 20683-20693, 2017
1292017
The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity
DE Foxler, KS Bridge, V James, TM Webb, M Mee, SCK Wong, Y Feng, ...
Nature cell biology 14 (2), 201-208, 2012
1022012
Regulation of the interferon-inducible eIF-2α protein kinase by small RNAs
MJ Clemens, KG Laing, IW Jeffrey, A Schofield, TV Sharp, A Elia, V Matys, ...
Biochimie 76 (8), 770-778, 1994
1021994
LIM domains-containing protein 1 (LIMD1), a tumor suppressor encoded at chromosome 3p21. 3, binds pRB and represses E2F-driven transcription
TV Sharp, F Munoz, D Bourboulia, N Presneau, E Darai, HW Wang, ...
Proceedings of the National Academy of Sciences 101 (47), 16531-16536, 2004
982004
The role of hypoxia in stem cell potency and differentiation
KE Hawkins, TV Sharp, TR McKay
Regenerative medicine 8 (6), 771-782, 2013
972013
SMG-1 and mTORC1 act antagonistically to regulate response to injury and growth in planarians
C Gonzalez-Estevez, DA Felix, MD Smith, J Paps, SJ Morley, V James, ...
PLoS genetics 8 (3), e1002619, 2012
972012
The M type K15 protein of Kaposi's sarcoma-associated herpesvirus regulates microRNA expression via its SH2-binding motif to induce cell migration and invasion
YH Tsai, MF Wu, YH Wu, SJ Chang, SF Lin, TV Sharp, HW Wang
Journal of virology 83 (2), 622-632, 2009
882009
The La antigen inhibits the activation of the interferoninducible protein kinase PKR by sequestering and unwinding double-stranded RNA
Q Xao, TV Sharp, IW Jeffrey, MC James, GJM Pruijn, WJ Venrooij, ...
Nucleic acids research 22 (13), 2512-2518, 1994
811994
LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencing
V James, Y Zhang, DE Foxler, CH De Moor, YW Kong, TM Webb, TJ Self, ...
Proceedings of the National Academy of Sciences 107 (28), 12499-12504, 2010
752010
The chromosome 3p21.3-encoded gene, LIMD1, is a critical tumor suppressor involved in human lung cancer development
TV Sharp, A Al-Attar, DE Foxler, L Ding, TQ de A. Vallim, Y Zhang, ...
Proceedings of the National Academy of Sciences 105 (50), 19932-19937, 2008
732008
Argonaute utilization for miRNA silencing is determined by phosphorylation-dependent recruitment of LIM-domain-containing proteins
KS Bridge, KM Shah, Y Li, DE Foxler, SCK Wong, DC Miller, KM Davidson, ...
Cell reports 20 (1), 173-187, 2017
672017
Homologous regions of the α subunit of eukaryotic translational initiation factor 2 (eIF2α) and the vaccinia virus K3L gene product interact with the same domain within the …
TV Sharp, JE Witzel, R Jagus
European journal of biochemistry 250 (1), 85-91, 1997
651997
CSN1 Somatic Mutations in Penile Squamous Cell Carcinoma
A Feber, DC Worth, A Chakravarthy, P de Winter, K Shah, M Arya, ...
Cancer research 76 (16), 4720-4727, 2016
562016
Activation of the interferon-inducible (2′-5′) oligoadenylate synthetase by the Epstein–Barr virus RNA, EBER-1
TV Sharp, DA Raine, DR Gewert, B Joshi, R Jagus, MJ Clemens
Virology 257 (2), 303-313, 1999
511999
The hypoxic tumor microenvironment: driving the tumorigenesis of non-small-cell lung cancer
JG Foster, SCK Wong, TV Sharp
Future Oncology 10 (16), 2659-2674, 2014
502014
BMI-1 extends proliferative potential of human bronchial epithelial cells while retaining their mucociliary differentiation capacity
MM Munye, A Shoemark, RA Hirst, JM Delhove, TV Sharp, TR McKay, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 312 (2 …, 2017
492017
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