Ahmed Ghallab
Ahmed Ghallab
Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, South Valley University
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Zitiert von
Zitiert von
Adverse outcome pathways: opportunities, limitations and open questions
M Leist, A Ghallab, R Graepel, R Marchan, R Hassan, SH Bennekou, ...
Archives of Toxicology 91, 3477-3505, 2017
The ascending pathophysiology of cholestatic liver disease
PLM Jansen, A Ghallab, N Vartak, R Reif, FG Schaap, J Hampe, ...
Hepatology 65 (2), 722-738, 2017
Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseases
A Ghallab, G Cellière, SG Henkel, D Driesch, S Hoehme, U Hofmann, ...
Journal of hepatology 64 (4), 860-871, 2016
A systematic evaluation of the use of physiologically based pharmacokinetic modeling for cross-species extrapolation
C Thiel, S Schneckener, M Krauss, A Ghallab, U Hofmann, T Kanacher, ...
Journal of pharmaceutical sciences 104 (1), 191-206, 2015
Integrated metabolic spatial‐temporal model for the prediction of ammonia detoxification during liver damage and regeneration
F Schliess, S Hoehme, SG Henkel, A Ghallab, D Driesch, J Böttger, ...
Hepatology 60 (6), 2040-2051, 2014
Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue
P Godoy, A Widera, W Schmidt-Heck, G Campos, C Meyer, C Cadenas, ...
Archives of toxicology 90, 2513-2529, 2016
In vitro test systems and their limitations
A Ghallab
Cellular clearance and biological activity of calciprotein particles depend on their maturation state and crystallinity
S Köppert, A Büscher, A Babler, A Ghallab, EM Buhl, E Latz, JG Hengstler, ...
Frontiers in immunology 9, 1991, 2018
Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations
W Albrecht, F Kappenberg, T Brecklinghaus, R Stoeber, R Marchan, ...
Archives of toxicology 93, 1609-1637, 2019
Bile microinfarcts in cholestasis are initiated by rupture of the apical hepatocyte membrane and cause shunting of bile to sinusoidal blood
A Ghallab, U Hofmann, S Sezgin, N Vartak, R Hassan, A Zaza, P Godoy, ...
Hepatology 69 (2), 666-683, 2019
The transcription factor CHOP, a central component of the transcriptional regulatory network induced upon CCl4 intoxication in mouse liver, is not a critical mediator …
G Campos, W Schmidt-Heck, A Ghallab, K Rochlitz, L Pütter, DB Medinas, ...
Archives of toxicology 88, 1267-1280, 2014
Gut microbiota depletion exacerbates cholestatic liver injury via loss of FXR signalling
KM Schneider, LS Candels, JR Hov, M Myllys, R Hassan, CV Schneider, ...
Nature Metabolism 3 (9), 1228-1241, 2021
In vivo imaging of systemic transport and elimination of xenobiotics and endogenous molecules in mice
R Reif, A Ghallab, L Beattie, G Günther, L Kuepfer, PM Kaye, ...
Archives of toxicology 91, 1335-1352, 2017
Intestinal dysbiosis amplifies acetaminophen-induced acute liver injury
KM Schneider, C Elfers, A Ghallab, CV Schneider, EJC Galvez, A Mohs, ...
Cellular and Molecular Gastroenterology and Hepatology 11 (4), 909-933, 2021
Physiologically-based modelling in mice suggests an aggravated loss of clearance capacity after toxic liver damage
A Schenk, A Ghallab, U Hofmann, R Hassan, M Schwarz, A Schuppert, ...
Scientific Reports 7 (1), 6224, 2017
Comparing in vitro human liver models to in vivo human liver using RNA-Seq
R Gupta, Y Schrooders, D Hauser, M van Herwijnen, W Albrecht, ...
Archives of Toxicology 95, 573-589, 2021
Influence of liver fibrosis on lobular zonation
A Ghallab, M Myllys, C H. Holland, A Zaza, W Murad, R Hassan, ...
Cells 8 (12), 1556, 2019
In vitro-in vivo correlation of gene expression alterations induced by liver carcinogens
T Heise, M Schug, D Storm, H Ellinger-Ziegelbauer, H J Ahr, B Hellwig, ...
Current medicinal chemistry 19 (11), 1721-1730, 2012
Spatio-temporal visualization of the distribution of acetaminophen as well as its metabolites and adducts in mouse livers by MALDI MSI
S Sezgin, R Hassan, S Zühlke, L Kuepfer, JG Hengstler, M Spiteller, ...
Archives of Toxicology 92, 2963-2977, 2018
The virtual liver: state of the art and future perspectives
D Drasdo, J Bode, U Dahmen, O Dirsch, S Dooley, R Gebhardt, A Ghallab, ...
Archives of toxicology 88, 2071-2075, 2014
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