| Adverse outcome pathways: opportunities, limitations and open questions M Leist, A Ghallab, R Graepel, R Marchan, R Hassan, SH Bennekou, ... Archives of Toxicology 91, 3477-3505, 2017 | 369 | 2017 |
| The ascending pathophysiology of cholestatic liver disease PLM Jansen, A Ghallab, N Vartak, R Reif, FG Schaap, J Hampe, ... Hepatology 65 (2), 722-738, 2017 | 327 | 2017 |
| A systematic evaluation of the use of physiologically based pharmacokinetic modeling for cross-species extrapolation C Thiel, S Schneckener, M Krauss, A Ghallab, U Hofmann, T Kanacher, ... Journal of pharmaceutical sciences 104 (1), 191-206, 2015 | 135 | 2015 |
| Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseases A Ghallab, G Celliere, SG Henkel, D Driesch, S Hoehme, U Hofmann, ... Journal of hepatology 64 (4), 860-871, 2016 | 128 | 2016 |
| Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue P Godoy, A Widera, W Schmidt-Heck, G Campos, C Meyer, C Cadenas, ... Archives of toxicology 90, 2513-2529, 2016 | 122 | 2016 |
| Integrated metabolic spatial‐temporal model for the prediction of ammonia detoxification during liver damage and regeneration F Schliess, S Hoehme, SG Henkel, A Ghallab, D Driesch, J Böttger, ... Hepatology 60 (6), 2040-2051, 2014 | 122 | 2014 |
| Cellular clearance and biological activity of calciprotein particles depend on their maturation state and crystallinity S Köppert, A Büscher, A Babler, A Ghallab, EM Buhl, E Latz, JG Hengstler, ... Frontiers in immunology 9, 1991, 2018 | 121 | 2018 |
| In vitro test systems and their limitations A Ghallab EXCLI journal 12, 1024, 2013 | 119 | 2013 |
| Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations W Albrecht, F Kappenberg, T Brecklinghaus, R Stoeber, R Marchan, ... Archives of toxicology 93, 1609-1637, 2019 | 111 | 2019 |
| Bile microinfarcts in cholestasis are initiated by rupture of the apical hepatocyte membrane and cause shunting of bile to sinusoidal blood A Ghallab, U Hofmann, S Sezgin, N Vartak, R Hassan, A Zaza, P Godoy, ... Hepatology 69 (2), 666-683, 2019 | 107 | 2019 |
| Gut microbiota depletion exacerbates cholestatic liver injury via loss of FXR signalling KM Schneider, LS Candels, JR Hov, M Myllys, R Hassan, CV Schneider, ... Nature Metabolism 3 (9), 1228-1241, 2021 | 92 | 2021 |
| Intestinal dysbiosis amplifies acetaminophen-induced acute liver injury KM Schneider, C Elfers, A Ghallab, CV Schneider, EJC Galvez, A Mohs, ... Cellular and Molecular Gastroenterology and Hepatology 11 (4), 909-933, 2021 | 92 | 2021 |
| Comparing in vitro human liver models to in vivo human liver using RNA-Seq R Gupta, Y Schrooders, D Hauser, M van Herwijnen, W Albrecht, ... Archives of toxicology 95, 573-589, 2021 | 81 | 2021 |
| The transcription factor CHOP, a central component of the transcriptional regulatory network induced upon CCl4 intoxication in mouse liver, is not a critical mediator … G Campos, W Schmidt-Heck, A Ghallab, K Rochlitz, L Pütter, DB Medinas, ... Archives of toxicology 88, 1267-1280, 2014 | 78 | 2014 |
| Physiologically-based modelling in mice suggests an aggravated loss of clearance capacity after toxic liver damage A Schenk, A Ghallab, U Hofmann, R Hassan, M Schwarz, A Schuppert, ... Scientific Reports 7 (1), 6224, 2017 | 72 | 2017 |
| In vivo imaging of systemic transport and elimination of xenobiotics and endogenous molecules in mice R Reif, A Ghallab, L Beattie, G Günther, L Kuepfer, PM Kaye, ... Archives of toxicology 91, 1335-1352, 2017 | 71 | 2017 |
| Sublethal necroptosis signaling promotes inflammation and liver cancer M Vucur, A Ghallab, AT Schneider, A Adili, M Cheng, M Castoldi, ... Immunity 56 (7), 1578-1595. e8, 2023 | 67 | 2023 |
| Influence of liver fibrosis on lobular zonation A Ghallab, M Myllys, C H. Holland, A Zaza, W Murad, R Hassan, ... Cells 8 (12), 1556, 2019 | 66 | 2019 |
| Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity A Ghallab, R Hassan, U Hofmann, A Friebel, Z Hobloss, L Brackhagen, ... Journal of Hepatology 77 (1), 71-83, 2022 | 60 | 2022 |
| Spatio-temporal visualization of the distribution of acetaminophen as well as its metabolites and adducts in mouse livers by MALDI MSI S Sezgin, R Hassan, S Zühlke, L Kuepfer, JG Hengstler, M Spiteller, ... Archives of Toxicology 92, 2963-2977, 2018 | 57 | 2018 |
Reham HassanForensic Medicine and Toxicology Department, Faculty of Veterinary Medicine, South Vally UniversityVerified email at vet.svu.edu.eg
