Robert James Thomas
Robert James Thomas
Wolfson School, Loughborough University
Verified email at lboro.ac.uk
Title
Cited by
Cited by
Year
Automated, scalable culture of human embryonic stem cells in feeder‐free conditions
RJ Thomas, D Anderson, A Chandra, NM Smith, LE Young, D Williams, ...
Biotechnology and Bioengineering 102 (6), 1636-1644, 2009
1562009
The effect of three-dimensional co-culture of hepatocytes and hepatic stellate cells on key hepatocyte functions in vitro
RJ Thomas, R Bhandari, DA Barrett, AJ Bennett, JR Fry, D Powe, ...
Cells Tissues Organs 181 (2), 67-79, 2005
1382005
Expansion of human mesenchymal stem cells on microcarriers
CJ Hewitt, K Lee, AW Nienow, RJ Thomas, M Smith, CR Thomas
Biotechnology letters 33 (11), 2325, 2011
1262011
Current understanding and challenges in bioprocessing of stem cell-based therapies for regenerative medicine
E Ratcliffe, RJ Thomas, DJ Williams
British medical bulletin 100 (1), 137, 2011
972011
Application of process quality engineering techniques to improve the understanding of the in vitro processing of stem cells for therapeutic use
RJ Thomas, PC Hourd, DJ Williams
Journal of biotechnology 136 (3-4), 148-155, 2008
722008
Manufacture of a human mesenchymal stem cell population using an automated cell culture platform
RJ Thomas, A Chandra, Y Liu, PC Hourd, PP Conway, DJ Williams
Cytotechnology 55 (1), 31-39, 2007
632007
Hepatic stellate cells on poly (DL-lactic acid) surfaces control the formation of 3D hepatocyte co-culture aggregates in vitro.
RJ Thomas, A Bennett, B Thomson, KM Shakesheff
European cells & materials 11, 16-26; discussion 26, 2006
522006
Precision manufacturing for clinical-quality regenerative medicines
DJ Williams, RJ Thomas, PC Hourd, A Chandra, E Ratcliffe, Y Liu, ...
Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2012
512012
Automated, serum-free production of CTX0E03: a therapeutic clinical grade human neural stem cell line
RJ Thomas, AD Hope, P Hourd, M Baradez, EA Miljan, JD Sinden, ...
Biotechnology letters 31 (8), 1167-1172, 2009
432009
A Novel Automated Bioreactor for Scalable Process Optimisation of Haematopoietic Stem Cell Culture
E Ratcliffe, KE Glen, VL Workman, AJ Stacey, RJ Thomas
Journal of Biotechnology, 2012
412012
Human‐induced pluripotent stem cells generate light responsive retinal organoids with variable and nutrient‐dependent efficiency
D Hallam, G Hilgen, B Dorgau, L Zhu, M Yu, S Bojic, P Hewitt, M Schmitt, ...
Stem Cells 36 (10), 1535-1551, 2018
402018
Cell culture automation and quality engineering: a necessary partnership to develop optimized manufacturing processes for cell-based therapies
RJ Thomas, A Chandra, PC Hourd, DJ Williams
JALA: Journal of the Association for Laboratory Automation 13 (3), 152-158, 2008
352008
Mesenchymal stem cell isolation from human umbilical cord tissue: understanding and minimizing variability in cell yield for process optimization
A Iftimia-Mander, P Hourd, R Dainty, RJ Thomas
Biopreservation and biobanking 11 (5), 291-298, 2013
332013
Investigating the feasibility of scale up and automation of human induced pluripotent stem cells cultured in aggregates in feeder free conditions
FAC Soares, A Chandra, RJ Thomas, RA Pedersen, L Vallier, DJ Williams
Journal of biotechnology 173, 53-58, 2014
232014
Comparability: manufacturing, characterization and controls, report of a UK regenerative medicine platform pluripotent stem cell platform workshop, trinity hall, cambridge, 14 …
DJ Williams, R Archer, P Archibald, I Bantounas, R Baptista, R Barker, ...
Regenerative medicine 11 (5), 483-492, 2016
182016
A quality-by-design approach to risk reduction and optimization for human embryonic stem cell cryopreservation processes
PD Mitchell, E Ratcliffe, P Hourd, DJ Williams, RJ Thomas
Tissue Engineering Part C: Methods 20 (12), 941-950, 2014
172014
Production of erythrocytes from directly isolated or Delta1 Notch ligand expanded CD34+ hematopoietic progenitor cells: process characterization, monitoring and implications …
KE Glen, VL Workman, F Ahmed, E Ratcliffe, AJ Stacey, RJ Thomas
Cytotherapy 15 (9), 1106-1117, 2013
142013
Translating cell-based regenerative medicines from research to successful products: challenges and solutions
Y Bayon, AA Vertès, V Ronfard, M Egloff, S Snykers, GF Salinas, ...
Tissue Engineering Part B: Reviews 20 (4), 246-256, 2014
122014
The productivity limit of manufacturing blood cell therapy in scalable stirred bioreactors
R Bayley, F Ahmed, K Glen, M McCall, A Stacey, R Thomas
Journal of tissue engineering and regenerative medicine 12 (1), e368-e378, 2018
112018
Application of response surface methodology to maximize the productivity of scalable automated human embryonic stem cell manufacture
E Ratcliffe, P Hourd, J Guijarro-Leach, E Rayment, DJ Williams, ...
Regenerative Medicine 8 (1), 39-48, 2013
112013
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