Nicholas J. Roberts
Nicholas J. Roberts
Assistant Professor, Department of Pathology, the Johns Hopkins University
Verified email at
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ATM mutations in patients with hereditary pancreatic cancer
NJ Roberts, Y Jiao, J Yu, L Kopelovich, GM Petersen, ML Bondy, ...
Cancer discovery 2 (1), 41-46, 2012
Intratumoral injection of Clostridium novyi-NT spores induces antitumor responses
NJ Roberts, L Zhang, F Janku, A Collins, RY Bai, V Staedtke, AW Rusk, ...
Science translational medicine 6 (249), 249ra111-249ra111, 2014
The predictive capacity of personal genome sequencing
NJ Roberts, JT Vogelstein, G Parmigiani, KW Kinzler, B Vogelstein, ...
Science translational medicine 4 (133), 133ra58-133ra58, 2012
Whole genome sequencing defines the genetic heterogeneity of familial pancreatic cancer
NJ Roberts, AL Norris, GM Petersen, ML Bondy, R Brand, S Gallinger, ...
Cancer discovery 6 (2), 166-175, 2016
Deleterious germline mutations in patients with apparently sporadic pancreatic adenocarcinoma
K Shindo, J Yu, M Suenaga, S Fesharakizadeh, C Cho, A Macgregor-Das, ...
Journal of Clinical Oncology 35 (30), 3382, 2017
Exomic Sequencing of Medullary Thyroid Cancer Reveals Dominant and Mutually Exclusive Oncogenic Mutations in RET and RAS
N Agrawal, Y Jiao, M Sausen, R Leary, C Bettegowda, NJ Roberts, ...
The Journal of Clinical Endocrinology & Metabolism 98 (2), E364-E369, 2013
BRCA1, BRCA2, PALB2, and CDKN2A mutations in familial pancreatic cancer: a PACGENE study
DB Zhen, KG Rabe, S Gallinger, S Syngal, AG Schwartz, MG Goggins, ...
Genetics in Medicine 17 (7), 569-577, 2014
Whole-Exome Sequencing Analyses of Inflammatory Bowel Disease− Associated Colorectal Cancers
AI Robles, G Traverso, M Zhang, NJ Roberts, MA Khan, C Joseph, ...
Gastroenterology 150 (4), 931-943, 2016
Systemic use of tumor necrosis factor alpha as an anticancer agent
NJ Roberts, S Zhou, LA Diaz, M Holdhoff
Oncotarget 2 (10), 739-751, 2011
IPMNs with co-occurring invasive cancers: neighbours but not always relatives
M Felsenstein, M NoŽ, DL Masica, W Hosoda, P Chianchiano, CG Fischer, ...
Gut 67 (9), 1652-1662, 2018
Aristolochic acid in the etiology of renal cell carcinoma
ML Hoang, CH Chen, PC Chen, NJ Roberts, KG Dickman, BH Yun, ...
Cancer Epidemiology Biomarkers & Prevention, cebp. 0219.2016, 2016
Familial and sporadic pancreatic cancer share the same molecular pathogenesis
AL Norris, NJ Roberts, S Jones, SJ Wheelan, N Papadopoulos, ...
Familial cancer 14 (1), 95-103, 2015
Intraductal papillary mucinous neoplasms arise from multiple independent clones, each with distinct mutations
CG Fischer, VB Guthrie, AM Braxton, L Zheng, P Wang, Q Song, JF Griffin, ...
Gastroenterology 157 (4), 1123-1137. e22, 2019
Mutations in the pancreatic secretory enzymes CPA1 and CPB1 are associated with pancreatic cancer
K Tamura, J Yu, T Hata, M Suenaga, K Shindo, T Abe, A MacGregor-Das, ...
Proceedings of the National Academy of Sciences 115 (18), 4767-4772, 2018
Clostridium novyi-NT in cancer therapy
V Staedtke, NJ Roberts, RY Bai, S Zhou
Genes & Diseases 3 (2), 144-152, 2016
Single‐cell sequencing defines genetic heterogeneity in pancreatic cancer precursor lesions
Y Kuboki, CG Fischer, V Beleva Guthrie, W Huang, J Yu, P Chianchiano, ...
The Journal of pathology 247 (3), 347-356, 2019
Genome-wide sequencing to identify the cause of hereditary cancer syndromes: With examples from familial pancreatic cancer
NJ Roberts, AP Klein
Cancer letters 340 (2), 227-233, 2013
A histomorphologic comparison of familial and sporadic pancreatic cancers
AD Singhi, H Ishida, SZ Ali, M Goggins, M Canto, CL Wolfgang, Z Meriden, ...
Pancreatology 15 (4), 387-391, 2015
Exome-wide association study of pancreatic cancer risk
RC Grant, RE Denroche, A Borgida, C Virtanen, N Cook, AL Smith, ...
Gastroenterology 154 (3), 719-722. e3, 2018
Cell division rates decrease with age, providing a potential explanation for the age-dependent deceleration in cancer incidence
C Tomasetti, J Poling, NJ Roberts, NR London, ME Pittman, MC Haffner, ...
Proceedings of the National Academy of Sciences 116 (41), 20482-20488, 2019
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