Galectin-1 is essential in tumor angiogenesis and is a target for antiangiogenesis therapy VLJL Thijssen, R Postel, RJ Brandwijk, RPM Dings, I Nesmelova, S Satijn, ... Proceedings of the National Academy of Sciences 103 (43), 15975-15980, 2006 | 583 | 2006 |
Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice RR Koenen, P Von Hundelshausen, IV Nesmelova, A Zernecke, EA Liehn, ... Nature medicine 15 (1), 97-103, 2009 | 498 | 2009 |
Platelet factor 4 promotes adhesion of hematopoietic progenitor cells and binds IL-8: novel mechanisms for modulation of hematopoiesis AZ Dudek, I Nesmelova, K Mayo, CM Verfaillie, S Pitchford, A Slungaard Blood 101 (12), 4687-4694, 2003 | 145 | 2003 |
Platelets regulate CD4+ T-cell differentiation via multiple chemokines in humans N Gerdes, L Zhu, M Ersoy, A Hermansson, P Hjemdahl, H Hu, ... Thrombosis and haemostasis 106 (08), 353-362, 2011 | 142 | 2011 |
Antitumor agent calixarene 0118 targets human galectin-1 as an allosteric inhibitor of carbohydrate binding RPM Dings, MC Miller, I Nesmelova, L Astorgues-Xerri, N Kumar, ... Journal of medicinal chemistry 55 (11), 5121-5129, 2012 | 137 | 2012 |
Lactose binding to galectin-1 modulates structural dynamics, increases conformational entropy, and occurs with apparent negative cooperativity IV Nesmelova, E Ermakova, VA Daragan, M Pang, M Menéndez, ... Journal of molecular biology 397 (5), 1209-1230, 2010 | 121 | 2010 |
Platelet factor 4 and interleukin-8 CXC chemokine heterodimer formation modulates function at the quaternary structural level IV Nesmelova, Y Sham, AZ Dudek, LI Van Eijk, G Wu, A Slungaard, ... Journal of Biological Chemistry 280 (6), 4948-4958, 2005 | 114 | 2005 |
Generalized concentration dependence of globular protein self‐diffusion coefficients in aqueous solutions IV Nesmelova, VD Skirda, VD Fedotov Biopolymers 63 (2), 132-140, 2002 | 102 | 2002 |
Intermittent hypoxia leads to functional reorganization of mitochondria and affects cellular bioenergetics in marine molluscs AV Ivanina, I Nesmelova, L Leamy, EP Sokolov, IM Sokolova Journal of Experimental Biology 219 (11), 1659-1674, 2016 | 94 | 2016 |
DDE transposases: Structural similarity and diversity IV Nesmelova, PB Hackett Advanced drug delivery reviews 62 (12), 1187-1195, 2010 | 91 | 2010 |
CXC and CC chemokines form mixed heterodimers: association free energies from molecular dynamics simulations and experimental correlations IV Nesmelova, Y Sham, J Gao, KH Mayo Journal of biological chemistry 283 (35), 24155-24166, 2008 | 90 | 2008 |
Design of a partial peptide mimetic of anginex with antiangiogenic and anticancer activity KH Mayo, RPM Dings, C Flader, I Nesmelova, B Hargittai, ... Journal of Biological Chemistry 278 (46), 45746-45752, 2003 | 81 | 2003 |
The carbohydrate-binding domain on galectin-1 is more extensive for a complex glycan than for simple saccharides: implications for galectin–glycan interactions at the cell surface MC Miller, IV Nesmelova, D Platt, A Klyosov, KH Mayo Biochemical Journal 421 (2), 211-221, 2009 | 74 | 2009 |
Topomimetics of amphipathic β-sheet and helix-forming bactericidal peptides neutralize lipopolysaccharide endotoxins X Chen, RPM Dings, I Nesmelova, S Debbert, JR Haseman, J Maxwell, ... Journal of medicinal chemistry 49 (26), 7754-7765, 2006 | 68 | 2006 |
Plant defensins from a structural perspective V Kovaleva, I Bukhteeva, OY Kit, IV Nesmelova International Journal of Molecular Sciences 21 (15), 5307, 2020 | 59 | 2020 |
Structural aspects of binding of α-linked digalactosides to human galectin-1 MC Miller, JP Ribeiro, V Roldós, S Martín-Santamaría, FJ Cañada, ... Glycobiology 21 (12), 1627-1641, 2011 | 59 | 2011 |
Self-diffusion and self-association of lysozyme molecules in solution IV Nesmelova, VD Fedotov Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 1998 | 55 | 1998 |
Lactose binding to human galectin-7 (p53-induced gene 1) induces long-range effects through the protein resulting in increased dimer stability and evidence for positive … E Ermakova, MC Miller, IV Nesmelova, L López-Merino, MA Berbís, ... Glycobiology 23 (5), 508-523, 2013 | 45 | 2013 |
The heterodimerization of platelet-derived chemokines J Carlson, SA Baxter, D Dréau, IV Nesmelova Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (1), 158-168, 2013 | 42 | 2013 |
Heat capacities and a snapshot of the energy landscape in protein GB1 from the pre-denaturation temperature dependence of backbone NH nanosecond fluctuations D Idiyatullin, I Nesmelova, VA Daragan, KH Mayo Journal of molecular biology 325 (1), 149-162, 2003 | 41 | 2003 |