| Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis K Iizuka, RK Bruick, G Liang, JD Horton, K Uyeda Proceedings of the National Academy of Sciences 101 (19), 7281-7286, 2004 | 910 | 2004 |
| Carbohydrate response element binding protein directly promotes lipogenic enzyme gene transcription S Ishii, K IIzuka, BC Miller, K Uyeda Proceedings of the National Academy of Sciences 101 (44), 15597-15602, 2004 | 509 | 2004 |
| ChREBP: a glucose-activated transcription factor involved in the development of metabolic syndrome K Iizuka, Y Horikawa Endocrine journal 55 (4), 617-624, 2008 | 258 | 2008 |
| Deficiency of carbohydrate-activated transcription factor ChREBP prevents obesity and improves plasma glucose control in leptin-deficient (ob/ob) mice K Iizuka, B Miller, K Uyeda American Journal of Physiology-Endocrinology and Metabolism 291 (2), E358-E364, 2006 | 246 | 2006 |
| Glucose induces FGF21 mRNA expression through ChREBP activation in rat hepatocytes K Iizuka, J Takeda, Y Horikawa FEBS letters 583 (17), 2882-2886, 2009 | 212 | 2009 |
| Overexpression of dominant-negative mutant hepatocyte nuclear factor-1α in pancreatic β-cells causes abnormal islet architecture with decreased expression of E-cadherin … K Yamagata, T Nammo, M Moriwaki, A Ihara, K Iizuka, Q Yang, T Satoh, ... Diabetes 51 (1), 114-123, 2002 | 186 | 2002 |
| Genetic variation in the hypoxia-inducible factor-1α gene is associated with type 2 diabetes in Japanese N Yamada, Y Horikawa, N Oda, K Iizuka, N Shihara, S Kishi, J Takeda The Journal of Clinical Endocrinology & Metabolism 90 (10), 5841-5847, 2005 | 135 | 2005 |
| The role of carbohydrate response element binding protein in intestinal and hepatic fructose metabolism K Iizuka Nutrients 9 (2), 181, 2017 | 91 | 2017 |
| Recent progress on the role of ChREBP in glucose and lipid metabolism K Iizuka Endocrine journal 60 (5), 543-555, 2013 | 84 | 2013 |
| Hepatic FoxO1 integrates glucose utilization and lipid synthesis through regulation of Chrebp O-glycosylation Y Ido-Kitamura, T Sasaki, M Kobayashi, HJ Kim, YS Lee, O Kikuchi, ... Public Library of Science 7 (10), e47231, 2012 | 82 | 2012 |
| ChREBP-mediated regulation of lipid metabolism: involvement of the gut microbiota, liver, and adipose tissue K Iizuka, K Takao, D Yabe Frontiers in endocrinology 11, 587189, 2020 | 78 | 2020 |
| The transcription factor carbohydrate-response element-binding protein (ChREBP): A possible link between metabolic disease and cancer K Iizuka Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (2), 474-485, 2017 | 75 | 2017 |
| Regulation of lipogenesis via BHLHB2/DEC1 and ChREBP feedback looping K Iizuka, Y Horikawa Biochemical and biophysical research communications 374 (1), 95-100, 2008 | 71 | 2008 |
| Carbohydrate-response element-binding protein deletion alters substrate utilization producing an energy-deficient liver SC Burgess, K Iizuka, NH Jeoung, RA Harris, Y Kashiwaya, RL Veech, ... Journal of Biological Chemistry 283 (3), 1670-1678, 2008 | 62 | 2008 |
| Krüppel-like factor-10 is directly regulated by carbohydrate response element-binding protein in rat primary hepatocytes K Iizuka, J Takeda, Y Horikawa Biochemical and biophysical research communications 412 (4), 638-643, 2011 | 51 | 2011 |
| Large‐scale analysis of glucocorticoid target genes in rat hypothalamus H Sato, Y Horikawa, K Iizuka, N Sakurai, T Tanaka, N Shihara, A Oshima, ... Journal of neurochemistry 106 (2), 805-814, 2008 | 49 | 2008 |
| Metabolic consequence of long-term exposure of pancreatic β cells to free fatty acid with special reference to glucose insensitivity K Iizuka, H Nakajima, M Namba, J Miyagawa, J Miyazaki, T Hanafusa, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1586 (1), 23-31, 2002 | 47 | 2002 |
| Hepatic overexpression of dominant negative Mlx improves metabolic profile in diabetes-prone C57BL/6J mice K Iizuka, J Takeda, Y Horikawa Biochemical and biophysical research communications 379 (2), 499-504, 2009 | 43 | 2009 |
| Feedback looping between ChREBP and PPARα in the regulation of lipid metabolism in brown adipose tissues K Iizuka, W Wu, Y Horikawa, M Saito, J Takeda Endocrine journal 60 (10), 1145-1153, 2013 | 41 | 2013 |
| ChREBP-knockout mice show sucrose intolerance and fructose malabsorption T Kato, K Iizuka, K Takao, Y Horikawa, T Kitamura, J Takeda Nutrients 10 (3), 340, 2018 | 38 | 2018 |
Daisuke YabeProfessor of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of MedicineVerified email at kuhp.kyoto-u.ac.jp
