Manfred Gessler
Manfred Gessler
Biocenter, Dev. Biochemistry, Wuerzburg University
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Zitiert von
Zitiert von
Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping
M Gessler, A Poustka, W Cavenee, RL Neve, SH Orkin, GAP Bruns
Nature 343 (6260), 774-778, 1990
The landscape of genomic alterations across childhood cancers
SN Gröbner, BC Worst, J Weischenfeldt, I Buchhalter, K Kleinheinz, ...
Nature 555 (7696), 321-327, 2018
A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease
BG Bruneau, G Nemer, JP Schmitt, F Charron, L Robitaille, S Caron, ...
Cell 106 (6), 709-721, 2001
The Notch target genes Hey1 and Hey2 are required for embryonic vascular development
A Fischer, N Schumacher, M Maier, M Sendtner, M Gessler
Genes & development 18 (8), 901-911, 2004
GLI3 zinc-finger gene interrupted by translocations in Greig syndrome families
A Vortkamp, M Gessler, KH Grzeschik
Nature 352, 539-540, 1991
Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease
S Saburi, I Hester, E Fischer, M Pontoglio, V Eremina, M Gessler, ...
Nature genetics 40 (8), 1010-1015, 2008
Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death
CR Bezzina, J Barc, Y Mizusawa, CA Remme, JB Gourraud, F Simonet, ...
Nature genetics 45 (9), 1044-1049, 2013
Delta–Notch—and then? Protein interactions and proposed modes of repression by Hes and Hey bHLH factors
A Fischer, M Gessler
Nucleic acids research 35 (14), 4583-4596, 2007
Frasier syndrome is caused by defective alternative splicing of WT1 leading to an altered ratio of WT1+/− KTS splice isoforms
B Klamt, A Koziell, F Poulat, P Wieacker, P Scambler, P Berta, M Gessler
Human molecular genetics 7 (4), 709-714, 1998
Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans
B Bielesz, Y Sirin, H Si, T Niranjan, A Gruenwald, S Ahn, H Kato, ...
The Journal of clinical investigation 120 (11), 4040-4054, 2010
Spectrum of hSNF5IINI1 somatic mutations in human cancer and genotype-phenotype correlations
N Sévenet, A Lellouch-Tubiana, D Schofield, K Hoang-Xuan, M Gessler, ...
Human molecular genetics 8 (13), 2359-2368, 1999
Hey genes: a novel subfamily of hairy-and Enhancer of split related genes specifically expressed during mouse embryogenesis
C Leimeister, A Externbrink, B Klamt, M Gessler
Mechanisms of development 85 (1-2), 173-177, 1999
Mutations in the SIX1/2 pathway and the DROSHA/DGCR8 miRNA microprocessor complex underlie high-risk blastemal type Wilms tumors
J Wegert, N Ishaque, R Vardapour, C Geörg, Z Gu, M Bieg, B Ziegler, ...
Cancer cell 27 (2), 298-311, 2015
Hypoxia-mediated activation of Dll4-Notch-Hey2 signaling in endothelial progenitor cells and adoption of arterial cell fate
H Diez, A Fischer, A Winkler, CJ Hu, AK Hatzopoulos, G Breier, M Gessler
Experimental cell research 313 (1), 1-9, 2007
Comparative analysis of the human and mouse Hey1 promoter: Hey genes are new Notch target genes
MM Maier, M Gessler
Biochemical and biophysical research communications 275 (2), 652-660, 2000
Rationale for the treatment of Wilms tumour in the UMBRELLA SIOP–RTSG 2016 protocol
MM Van Den Heuvel-eibrink, JA Hol, K Pritchard-Jones, H Van Tinteren, ...
Nature reviews urology 14 (12), 743-752, 2017
Integrated regulation of Toll-like receptor responses by Notch and interferon-γ pathways
X Hu, AY Chung, I Wu, J Foldi, J Chen, JD Ji, T Tateya, YJ Kang, J Han, ...
Immunity 29 (5), 691-703, 2008
Sarcoma classification by DNA methylation profiling
C Koelsche, D Schrimpf, D Stichel, M Sill, F Sahm, DE Reuss, M Blattner, ...
Nature communications 12 (1), 498, 2021
Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti
A Doetzlhofer, ML Basch, T Ohyama, M Gessler, AK Groves, N Segil
Developmental cell 16 (1), 58-69, 2009
Developmental expression patterns of mouse sFRP genes encoding members of the secreted frizzled related protein family
C Leimeister, A Bach, M Gessler
Mechanisms of development 75 (1-2), 29-42, 1998
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