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Michael Feldkamp, PhD
Michael Feldkamp, PhD
Scientist, Janssen R&D
Verified email at its.jnj.com
Title
Cited by
Cited by
Year
Calmodulin mutations associated with recurrent cardiac arrest in infants
L Crotti, CN Johnson, E Graf, GM De Ferrari, BF Cuneo, M Ovadia, ...
Circulation 127 (9), 1009-1017, 2013
4132013
ETAA1 acts at stalled replication forks to maintain genome integrity
TE Bass, JW Luzwick, G Kavanaugh, C Carroll, H Dungrawala, GG Glick, ...
Nature cell biology 18 (11), 1185-1195, 2016
2572016
Structural and energetic determinants of apo calmodulin binding to the IQ motif of the NaV1. 2 voltage-dependent sodium channel
MD Feldkamp, L Yu, MA Shea
Structure 19 (5), 733-747, 2011
1032011
Discovery of a potent inhibitor of replication protein a protein–protein interactions using a fragment-linking approach
AO Frank, MD Feldkamp, JP Kennedy, AG Waterson, NF Pelz, JD Patrone, ...
Journal of medicinal chemistry 56 (22), 9242-9250, 2013
712013
Thermodynamics and kinetics for base-pair opening in the P1 duplex of the Tetrahymena group I ribozyme
JH Lee, A Pardi
Nucleic acids research 35 (9), 2965-2974, 2007
662007
Discovery of a potent stapled helix peptide that binds to the 70N domain of replication protein A
AO Frank, B Vangamudi, MD Feldkamp, EM Souza-Fagundes, ...
Journal of medicinal chemistry 57 (6), 2455-2461, 2014
612014
HEXIM1 is a promiscuous double-stranded RNA-binding protein and interacts with RNAs in addition to 7SK in cultured cells
Q Li, JJ Cooper, GH Altwerger, MD Feldkamp, MA Shea, DH Price
Nucleic acids research 35 (8), 2503-2512, 2007
582007
Effects of human deafness γ-actin mutations (DFNA20/26) on actin function
KE Bryan, KK Wen, M Zhu, ND Rendtorff, M Feldkamp, L Tranebjaerg, ...
Journal of biological chemistry 281 (29), 20129-20139, 2006
502006
A high-throughput fluorescence polarization anisotropy assay for the 70N domain of replication protein A
EM Souza-Fagundes, AO Frank, MD Feldkamp, DC Dorset, WJ Chazin, ...
Analytical biochemistry 421 (2), 742-749, 2012
462012
Structural analysis of replication protein A recruitment of the DNA damage response protein SMARCAL1
MD Feldkamp, AC Mason, BF Eichman, WJ Chazin
Biochemistry 53 (18), 3052-3061, 2014
442014
Allosteric effects of the antipsychotic drug trifluoperazine on the energetics of calcium binding by calmodulin
MD Feldkamp, SE O'Donnell, L Yu, MA Shea
Proteins: Structure, Function, and Bioinformatics 78 (10), 2265-2282, 2010
382010
Dissecting the binding energy epitope of a high-affinity variant of human growth hormone: cooperative and additive effects from combining mutations from independently selected …
B Bernat, M Sun, M Dwyer, M Feldkamp, AA Kossiakoff
Biochemistry 43 (20), 6076-6084, 2004
322004
Discovery of protein–protein interaction inhibitors of replication protein A
JD Patrone, JP Kennedy, AO Frank, MD Feldkamp, B Vangamudi, ...
ACS medicinal chemistry letters 4 (7), 601-605, 2013
292013
Calcium triggers reversal of calmodulin on nested anti-parallel sites in the IQ motif of the neuronal voltage-dependent sodium channel NaV1. 2
L Hovey, CA Fowler, R Mahling, Z Lin, MS Miller, DC Marx, JB Yoder, ...
Biophysical chemistry 224, 1-19, 2017
262017
Surface reengineering of RPA70N enables cocrystallization with an inhibitor of the replication protein A interaction motif of ATR interacting protein
MD Feldkamp, AO Frank, JP Kennedy, JD Patrone, B Vangamudi, ...
Biochemistry 52 (37), 6515-6524, 2013
232013
Identification and optimization of anthranilic acid based inhibitors of replication protein A
JD Patrone, NF Pelz, BS Bates, EM Souza‐Fagundes, B Vangamudi, ...
ChemMedChem 11 (8), 893-899, 2016
172016
Diphenylpyrazoles as replication protein a inhibitors
AG Waterson, JP Kennedy, JD Patrone, NF Pelz, MD Feldkamp, AO Frank, ...
ACS Medicinal Chemistry Letters 6 (2), 140-145, 2015
172015
Opposing orientations of the anti‐psychotic drug trifluoperazine selected by alternate conformations of M 144 in calmodulin
MD Feldkamp, L Gakhar, N Pandey, MA Shea
Proteins: Structure, Function, and Bioinformatics 83 (5), 989-996, 2015
132015
NMR studies of the interaction of calmodulin with IQ motif peptides
SM Damo, MD Feldkamp, B Chagot, WJ Chazin
Calcium-Binding Proteins and RAGE: From Structural Basics to Clinical …, 2013
92013
Simian virus Large T antigen interacts with the N-terminal domain of the 70 kD subunit of Replication Protein A in the same mode as multiple DNA damage response factors
B Ning, MD Feldkamp, D Cortez, WJ Chazin, KL Friedman, E Fanning
PLoS One 10 (2), e0116093, 2015
82015
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