| Renal biomarker qualification submission: a dialog between the FDA-EMEA and Predictive Safety Testing Consortium F Dieterle, F Sistare, F Goodsaid, M Papaluca, JS Ozer, CP Webb, W Baer, ... Nature biotechnology 28 (5), 455-462, 2010 | 469 | 2010 |
| Increased serum enzyme levels associated with kupffer cell reduction with no signs of hepatic or skeletal muscle injury ZA Radi, PH Koza-Taylor, RR Bell, LA Obert, HA Runnels, JS Beebe, ... The American journal of pathology 179 (1), 240-247, 2011 | 163 | 2011 |
| Targeted disruption of murine organic anion-transporting polypeptide 1b2 (Oatp1b2/Slco1b2) significantly alters disposition of prototypical drug substrates pravastatin and rifampin H Zaher, HEM zu Schwabedissen, RG Tirona, ML Cox, LA Obert, ... Molecular pharmacology 74 (2), 320-329, 2008 | 139 | 2008 |
| Towards consensus practices to qualify safety biomarkers for use in early drug development FD Sistare, F Dieterle, S Troth, DJ Holder, D Gerhold, ... Nature biotechnology 28 (5), 446-454, 2010 | 136 | 2010 |
| Induction of accelerated feline immunodeficiency virus disease by acute-phase virus passage LJ Diehl, CK Mathiason-Dubard, LL O'Neil, LA Obert, EA Hoover Journal of virology 69 (10), 6149-6157, 1995 | 108 | 1995 |
| Mucosal transmission of cell-associated and cell-free feline immunodeficiency virus MJO BURKHARD, LA OBERT, LL O'NEIL, LJ DIEHL, EA HOOVER AIDS research and human retroviruses 13 (4), 347-355, 1997 | 79 | 1997 |
| An immunohistochemical approach to differentiate hepatic lipidosis from hepatic phospholipidosis in rats LA Obert, GP Sobocinski, WF Bobrowski, AL Metz, MD Rolsma, ... Toxicologic pathology 35 (5), 728-734, 2007 | 65 | 2007 |
| Quantitative gene expression analysis in a nonhuman primate model of antibiotic-induced nephrotoxicity JW Davis II, FM Goodsaid, CM Bral, LA Obert, G Mandakas, CE Garner II, ... Toxicology and applied pharmacology 200 (1), 16-26, 2004 | 64 | 2004 |
| Belantamab Mafodotin (GSK2857916) Drives Immunogenic Cell Death and Immune-mediated Antitumor Responses In Vivo R Montes de Oca, AS Alavi, N Vitali, S Bhattacharya, C Blackwell, K Patel, ... Molecular cancer therapeutics 20 (10), 1941-1955, 2021 | 57 | 2021 |
| Targeting CLDN18. 2 by CD3 bispecific and ADC modalities for the treatments of gastric and pancreatic cancer G Zhu, D Foletti, X Liu, S Ding, J Melton Witt, A Hasa-Moreno, M Rickert, ... Scientific reports 9 (1), 8420, 2019 | 57 | 2019 |
| Liver microvascular injury and thrombocytopenia of antibody–calicheamicin conjugates in cynomolgus monkeys—mechanism and monitoring M Guffroy, H Falahatpisheh, K Biddle, J Kreeger, L Obert, K Walters, ... Clinical Cancer Research 23 (7), 1760-1770, 2017 | 51 | 2017 |
| Early pathogenesis of transmucosal feline immunodeficiency virus infection LA Obert, EA Hoover Journal of virology 76 (12), 6311-6322, 2002 | 51 | 2002 |
| The Role of Hypoxia in 2-Butoxyethanol–Induced Hemangiosarcoma D Laifenfeld, A Gilchrist, D Drubin, M Jorge, SF Eddy, BP Frushour, ... Toxicological Sciences 113 (1), 254-266, 2010 | 50 | 2010 |
| Feline immunodeficiency virus clade C mucosal transmission and disease courses LA Obert, EA Hoover AIDS research and human retroviruses 16 (7), 677-688, 2000 | 46 | 2000 |
| A review of specific biomarkers of chronic renal injury and their potential application in nonclinical safety assessment studies LA Obert, SA Elmore, D Ennulat, KS Frazier Toxicologic pathology 49 (5), 996-1023, 2021 | 41 | 2021 |
| Drug-induced glomerulonephritis: the spectre of biotherapeutic and antisense oligonucleotide immune activation in the kidney KS Frazier, LA Obert Toxicologic Pathology 46 (8), 904-917, 2018 | 36 | 2018 |
| Relationship of lymphoid lesions to disease course in mucosal feline immunodeficiency virus type C infection LA Obert, EA Hoover Veterinary pathology 37 (5), 386-401, 2000 | 36 | 2000 |
| Malignant histiocytosis in a domestic cat: cytomorphologic and immunohistochemical features RM Walton, DE Brown, MJ Burkhard, KB Donnelly, AA Frank, LA Obert, ... Veterinary Clinical Pathology 26 (2), 56-60, 1997 | 31 | 1997 |
| Identification of Potential Genomic Biomarkers of Hepatotoxicity Caused by Reactive Metabolites of N-Methylformamide: Application of Stable Isotope Labeled … A Mutlib, P Jiang, J Atherton, L Obert, S Kostrubsky, S Madore, S Nelson Chemical research in toxicology 19 (10), 1270-1283, 2006 | 26 | 2006 |
| Regression of feline immunodeficiency virus infection LL O'NEIL, MJ Burkhard, LA Obert, EA Hoover AIDS research and human retroviruses 13 (8), 713-718, 1997 | 24 | 1997 |
