Dynamic landscape and regulation of RNA editing in mammals MH Tan, Q Li, R Shanmugam, R Piskol, J Kohler, AN Young, KI Liu, ... Nature 550 (7675), 249-254, 2017 | 529 | 2017 |
Systematic evaluation of CRISPR-Cas systems reveals design principles for genome editing in human cells Y Wang, KI Liu, NAB Sutrisnoh, H Srinivasan, J Zhang, J Li, F Zhang, ... Genome biology 19, 1-16, 2018 | 88 | 2018 |
Cytosine methylation of tRNA-Asp by DNMT2 has a role in translation of proteins containing poly-Asp sequences R Shanmugam, J Fierer, S Kaiser, M Helm, TP Jurkowski, A Jeltsch Cell discovery 1 (1), 1-10, 2015 | 79 | 2015 |
A human expression system based on HEK293 for the stable production of recombinant erythropoietin CL Chin, JB Goh, H Srinivasan, KI Liu, A Gowher, R Shanmugam, HL Lim, ... Scientific reports 9 (1), 16768, 2019 | 52 | 2019 |
Somatic cancer mutations in the DNMT2 tRNA methyltransferase alter its catalytic properties W Elhardt, R Shanmugam, TP Jurkowski, A Jeltsch Biochimie 112, 66-72, 2015 | 48 | 2015 |
Mapping the tRNA binding site on the surface of human DNMT2 methyltransferase TP Jurkowski, R Shanmugam, M Helm, A Jeltsch Biochemistry 51 (22), 4438-4444, 2012 | 33 | 2012 |
The Dnmt2 RNA methyltransferase homolog of Geobacter sulfurreducens specifically methylates tRNA-Glu R Shanmugam, M Aklujkar, M Schäfer, R Reinhardt, O Nickel, G Reuter, ... Nucleic acids research 42 (10), 6487-6496, 2014 | 32 | 2014 |
Laboratory MH Tan, Q Li, R Shanmugam, R Piskol, J Kohler, AN Young, KI Liu, ... Data Analysis &Coordinating Center (LDACC)—Analysis Working Group, 249-254, 0 | 31 | |
SRSF9 selectively represses ADAR2-mediated editing of brain-specific sites in primates R Shanmugam, F Zhang, H Srinivasan, JL Charles Richard, KI Liu, ... Nucleic acids research 46 (14), 7379-7395, 2018 | 25 | 2018 |
Genome-wide screens identify specific drivers of mutant hTERT promoters R Shanmugam, MB Ozturk, JL Low, SC Akincilar, JYH Chua, ... Proceedings of the National Academy of Sciences 119 (3), e2105171119, 2022 | 12 | 2022 |
Consortium MH Tan, Q Li, R Shanmugam, R Piskol, J Kohler, AN Young, KI Liu, ... G., Chawla, A., Del Sal, G., Peltz, G., Brunet, A., Conrad, DF, Samuel, CE …, 2017 | 6 | 2017 |
Laboratory, Data Analysis & Coordinating Center (LDACC)—Analysis Working Group, Statistical Methods groups—Analysis Working Group, Enhancing GTEx (eGTEx) groups, NIH Common … MH Tan, Q Li, R Shanmugam, R Piskol, J Kohler, AN Young, KI Liu, ... | 4 | 2017 |
I's (Inosine) on RNA by ADAR enzymes: An epitranscriptomic mutation process in action R Shanmugam ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 63, 12-12, 2022 | | 2022 |
SRSF9 selectively represses ADAR2-mediated editing of brain-specific sites in primates F Zhang, H Srinivasan, R Shanmugam, JL Charles Richard, X Zhang, ... | | 2018 |
Role of tRNA cytosine-C5 methylation in protein biosynthesis and disease R Shanmugam, W Elhardt, J Fierer, S Kaiser, M Helm, TP Jurkowski, ... FEBS JOURNAL 282, 17-17, 2015 | | 2015 |
Biochemical characterisation of tRNA-Asp methyltransferase Dnmt2 and its physiological significance R Shanmugam | | 2014 |