Effects of salts from the Hofmeister series on the conformational stability, aggregation propensity, and local flexibility of an IgG1 monoclonal antibody R Majumdar, P Manikwar, JM Hickey, HS Samra, HA Sathish, SM Bishop, ... Biochemistry 52 (19), 3376-3389, 2013 | 121 | 2013 |
Correlating excipient effects on conformational and storage stability of an IgG1 monoclonal antibody with local dynamics as measured by hydrogen/deuterium-exchange mass … P Manikwar, R Majumdar, JM Hickey, SV Thakkar, HS Samra, HA Sathish, ... Journal of pharmaceutical sciences 102 (7), 2136-2151, 2013 | 102 | 2013 |
Analytical lessons learned from selected therapeutic protein drug comparability studies M Federici, A Lubiniecki, P Manikwar, DB Volkin Biologicals 41 (3), 131-147, 2013 | 81 | 2013 |
Minimizing carry-over in an online pepsin digestion system used for the H/D exchange mass spectrometric analysis of an IgG1 monoclonal antibody R Majumdar, P Manikwar, JM Hickey, J Arora, CR Middaugh, DB Volkin, ... Journal of the American Society for Mass Spectrometry 23 (12), 2140-2148, 2012 | 77 | 2012 |
cIBR effectively targets nanoparticles to LFA-1 on acute lymphoblastic T cells C Chittasupho, P Manikwar, JP Krise, TJ Siahaan, C Berkland Molecular pharmaceutics 7 (1), 146-155, 2010 | 47 | 2010 |
Antigen‐specific blocking of CD4‐specific immunological synapse formation using BPI and current therapies for autoimmune diseases P Manikwar, P Kiptoo, AH Badawi, B Büyüktimkin, TJ Siahaan Medicinal research reviews 32 (4), 727-764, 2012 | 35 | 2012 |
Both reversible self-association and structural changes underpin molecular viscoelasticity of mAb solutions PS Sarangapani, J Weaver, A Parupudi, TMD Besong, GG Adams, ... Journal of pharmaceutical sciences 105 (12), 3496-3506, 2016 | 27 | 2016 |
Rapid identification of fluorochrome modification sites in proteins by LC ESI-Q-TOF mass spectrometry P Manikwar, T Zimmerman, FJ Blanco, TD Williams, TJ Siahaan Bioconjugate chemistry 22 (7), 1330-1336, 2011 | 20 | 2011 |
Mechanism of a decrease in potency for the recombinant influenza A virus hemagglutinin H3 antigen during storage JM Hickey, KM Holtz, P Manikwar, SB Joshi, CE Mcpherson, B Buckland, ... Journal of pharmaceutical sciences 103 (3), 821-827, 2014 | 17 | 2014 |
Utilization of I-domain of LFA-1 to Target Drug and Marker Molecules to Leukocytes P Manikwar, BA Tejo, H Shinogle, DS Moore, T Zimmerman, F Blanco, ... Theranostics 1, 277, 2011 | 16 | 2011 |
Characterization of a novel bispecific antibody with improved conformational and chemical stability P Manikwar, SHR Mulagapati, S Kasturirangan, K Moez, GJ Rainey, ... Journal of Pharmaceutical Sciences 109 (1), 220-232, 2020 | 15 | 2020 |
I-domain-antigen conjugate (IDAC) for delivering antigenic peptides to APC: synthesis, characterization, and in vivo EAE suppression P Manikwar, B Büyüktimkin, P Kiptoo, AH Badawi, NA Galeva, ... Bioconjugate chemistry 23 (3), 509-517, 2012 | 10 | 2012 |
Vaccinelike and prophylactic treatments of EAE with novel I-domain antigen conjugates (IDAC): targeting multiple antigenic peptides to APC B Büyüktimkin, P Manikwar, PK Kiptoo, AH Badawi, JM Stewart Jr, ... Molecular pharmaceutics 10 (1), 297-306, 2013 | 7 | 2013 |
Bispecific binding proteins and uses thereof S Kasturirangan, C Gao, G Rainey, M Morrow, CL Dobson, S Drabic, ... US Patent 10,457,732, 2019 | 6 | 2019 |
Preformulation characterization, stabilization, and formulation design for the acrylodan-labeled glucose-binding protein SM4-AC N Sahni, R Chaudhuri, JM Hickey, P Manikwar, A D’Souza, A Metters, ... Journal of Pharmaceutical Sciences 106 (5), 1197-1210, 2017 | 4 | 2017 |
Bispecific binding proteins and uses thereof S Kasturirangan, C Gao, G Rainey, M Morrow, CL Dobson, S Drabic, ... US Patent 11,279,759, 2022 | 2 | 2022 |
Sensitivity and uncertainty analysis of micro-flow imaging for sub-visible particle measurements using artificial neural network S Poozesh, F Cannavò, P Manikwar Pharmaceutical Research 40 (3), 721-733, 2023 | 1 | 2023 |
Bispecific binding proteins and uses thereof S Kasturirangan, C Gao, G Rainey, M Morrow, CL Dobson, S Drabic, ... US Patent App. 17/550,219, 2022 | 1 | 2022 |
Bispecific binding proteins and uses thereof S Kasturirangan, C Gao, G Rainey, M Morrow, CL Dobson, S Drabic, ... | 1 | 2020 |
Bispecific binding proteins and uses thereof S Kasturirangan, C Gao, G Rainey, M Morrow, CL Dobson, S Drabic, ... US Patent App. 17/364,539, 2024 | | 2024 |