| Differentiation imbalance in single oesophageal progenitor cells causes clonal immortalization and field change MP Alcolea, P Greulich, A Wabik, J Frede, BD Simons, PH Jones Nature cell biology 16 (6), 612-619, 2014 | 178 | 2014 |
| Ovarian cancer: Ion channel and aquaporin expression as novel targets of clinical potential J Frede, SP Fraser, G Oskay-Özcelik, Y Hong, EI Braicu, J Sehouli, ... European journal of cancer 49 (10), 2331-2344, 2013 | 80 | 2013 |
| A single dividing cell population with imbalanced fate drives oesophageal tumour growth J Frede, P Greulich, T Nagy, BD Simons, PH Jones Nature cell biology 18 (9), 967-978, 2016 | 61 | 2016 |
| Genomic discovery and clonal tracking in multiple myeloma by cell-free DNA sequencing G Guo, NS Raje, C Seifer, J Kloeber, R Isenhart, G Ha, AJ Yee, ... Leukemia 32 (8), 1838-1841, 2018 | 53 | 2018 |
| Single-cell RNA-seq reveals developmental plasticity with coexisting oncogenic states and immune evasion programs in ETP-ALL P Anand, A Guillaumet-Adkins, V Dimitrova, H Yun, Y Drier, N Sotudeh, ... Blood, The Journal of the American Society of Hematology 137 (18), 2463-2480, 2021 | 41 | 2021 |
| Dynamic transcriptional reprogramming leads to immunotherapeutic vulnerabilities in myeloma J Frede, P Anand, N Sotudeh, RA Pinto, MS Nair, H Stuart, AJ Yee, ... Nature cell biology 23 (11), 1199-1211, 2021 | 28 | 2021 |
| Single-Cell Profiling Reveals Metabolic Reprogramming as a Resistance Mechanism in BRAF-Mutated Multiple Myeloma JM Waldschmidt, JA Kloeber, P Anand, J Frede, A Kokkalis, V Dimitrova, ... Clinical Cancer Research 27 (23), 6432-6444, 2021 | 23 | 2021 |
| Loss of metabolic fitness drives tumor resistance after CAR-NK cell therapy and can be overcome by cytokine engineering L Li, V Mohanty, J Dou, Y Huang, PP Banerjee, Q Miao, JG Lohr, ... Science Advances 9 (30), eadd6997, 2023 | 20 | 2023 |
| Mutation, clonal fitness and field change in epithelial carcinogenesis J Frede, DJ Adams, PH Jones The Journal of pathology 234 (3), 296-301, 2014 | 18 | 2014 |
| Cell-free DNA for the detection of emerging treatment failure in relapsed/refractory multiple myeloma JM Waldschmidt, AJ Yee, T Vijaykumar, RA Pinto, J Frede, P Anand, ... Leukemia 36 (4), 1078-1087, 2022 | 15 | 2022 |
| Esophageal stem cells and genetics/epigenetics in esophageal cancer D Croagh, J Frede, PH Jones, P Kaur, C Partensky, WA Phillips Annals of the New York Academy of Sciences 1325 (1), 8-14, 2014 | 11 | 2014 |
| Permission to proliferate J Frede, PH Jones Science 342 (6163), 1183-1184, 2013 | 5 | 2013 |
| Regulatory programs of B-cell activation and germinal center reaction allow B-ALL escape from CD19 CAR T-cell therapy NG Im, A Guillaumet-Adkins, M Wal, AJ Rogers, J Frede, CC Havig, ... Cancer immunology research 10 (9), 1055-1068, 2022 | 4 | 2022 |
| Dual role of signaling pathways in myeloma requires cell-type specific targeting of ligand-receptor interactions. P Hernandez-Lopez, T Vijaykumar, P Anand, D Auclair, J Frede, ... Blood Advances, bloodadvances. 2023011463, 2024 | | 2024 |
| P324: CELL PLASTICITY PREDETERMINES TREATMENT RESPONSE IN T-ALL V Dimitrova, J Frede, A Montanaro, S Potdar, H Stuart, N Sotoudeh, ... HemaSphere 7 (S3), e0988081, 2023 | | 2023 |
| S188: CAR-T CELLS SHAPE THE IMMUNOLOGICAL POTENTIAL OF THE TUMOR MICROENVIRONMENT J Frede, J Poller, K Shi, H Stuart, N Sotoudeh, K Lim, C Wiggers, ... HemaSphere 7 (Suppl), 2023 | | 2023 |
| Single-Cell Multi-Omics Reveals Immune Microenvironment Alterations in T-Cell Acute Lymphoblastic Leukemia CRM Wiggers, EY Cho, J Hegel, J Frede, H Stuart, KK Lim, Y Pikman, ... Blood 140 (Supplement 1), 9192-9193, 2022 | | 2022 |
| Nivolumab-Based Salvage Therapy to Restore T Cell Fitness in Penta-Refractory Multiple Myeloma with Relapse to Anti-BCMA CAR T Cell Therapy JM Waldschmidt, S Arora, T Vijaykumar, N Sotudeh, P Anand, H Stuart, ... Blood 140 (Supplement 1), 9925-9926, 2022 | | 2022 |
| Cellular Plasticity As Mechanisms to Escape from NOTCH1-Inhibition in T-ALL V Dimitrova, N Sotudeh, B Knoechel, JG Lohr, A Montanaro, SV Potdar, ... Blood 140 (Supplement 1), 3461-3462, 2022 | | 2022 |
| Maturity State and MCL-1 Dependence Predetermines Response to NOTCH1 Inhibition in T-ALL V Dimitrova, N Sotudeh, A Montanaro, H Yun, SV Potdar, A Van Scoyk, ... Blood 138 (Supplement 1), 3484-3484, 2021 | | 2021 |
Philip JonesWellcome Trust Sanger Institute & Oncology Department, University of CambridgeVerified email at sanger.ac.uk
