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Housheng Hansen He
Housheng Hansen He
Princess Margaret Cancer Centre, University Health Network; Department of Medical Biophysics
Bestätigte E-Mail-Adresse bei uhnresearch.ca - Startseite
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EZH2 Oncogenic Activity in Castration-Resistant Prostate Cancer Cells Is Polycomb-Independent
K Xu, ZJ Wu, AC Groner, HH He, C Cai, RT Lis, X Wu, EC Stack, M Loda, ...
Science 338 (6113), 1465-1469, 2012
9772012
Genomic hallmarks and structural variation in metastatic prostate cancer
DA Quigley, HX Dang, SG Zhao, P Lloyd, R Aggarwal, JJ Alumkal, A Foye, ...
Cell 174 (3), 758-769. e9, 2018
7052018
Genomic hallmarks of localized, non-indolent prostate cancer
M Fraser, VY Sabelnykova, TN Yamaguchi, LE Heisler, J Livingstone, ...
Nature 541 (7637), 359-364, 2017
6322017
Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer
S Shu, CY Lin, HH He, RM Witwicki, DP Tabassum, JM Roberts, ...
Nature 529 (7586), 413-417, 2016
6282016
LSD1 ablation stimulates anti-tumor immunity and enables checkpoint blockade
W Sheng, MW LaFleur, TH Nguyen, S Chen, A Chakravarthy, JR Conway, ...
Cell 174 (3), 549-563. e19, 2018
5992018
Nucleosome dynamics define transcriptional enhancers
HH He, CA Meyer, H Shin, ST Bailey, G Wei, Q Wang, Y Zhang, K Xu, ...
Nature genetics 42 (4), 343-347, 2010
5612010
Androgen receptor gene expression in prostate cancer is directly suppressed by the androgen receptor through recruitment of lysine-specific demethylase 1
C Cai, HH He, S Chen, I Coleman, H Wang, Z Fang, S Chen, PS Nelson, ...
Cancer cell 20 (4), 457-471, 2011
5172011
8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC
N Ahmadiyeh, MM Pomerantz, C Grisanzio, P Herman, L Jia, V Almendro, ...
Proceedings of the National academy of sciences 107 (21), 9742-9746, 2010
4492010
Widespread and functional RNA circularization in localized prostate cancer
S Chen, V Huang, X Xu, J Livingstone, F Soares, J Jeon, Y Zeng, JT Hua, ...
Cell 176 (4), 831-843. e22, 2019
3782019
Colorectal cancer cells enter a diapause-like DTP state to survive chemotherapy
SK Rehman, J Haynes, E Collignon, KR Brown, Y Wang, AML Nixon, ...
Cell 184 (1), 226-242. e21, 2021
3542021
GlcNAcylation of histone H2B facilitates its monoubiquitination
R Fujiki, W Hashiba, H Sekine, A Yokoyama, T Chikanishi, S Ito, Y Imai, ...
Nature, 2011
3512011
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing
T Fei, Y Chen, T Xiao, W Li, L Cato, P Zhang, MB Cotter, M Bowden, ...
Proceedings of the National Academy of Sciences 114 (26), E5207-E5215, 2017
3222017
Tet3 CXXC domain and dioxygenase activity cooperatively regulate key genes for Xenopus eye and neural development
Y Xu, C Xu, A Kato, W Tempel, JG Abreu, C Bian, Y Hu, D Hu, B Zhao, ...
Cell 151 (6), 1200-1213, 2012
3192012
Risk SNP-mediated promoter-enhancer switching drives prostate cancer through lncRNA PCAT19
JT Hua, M Ahmed, H Guo, Y Zhang, S Chen, F Soares, J Lu, S Zhou, ...
Cell 174 (3), 564-575. e18, 2018
3072018
Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progression
S Chen, G Zhu, Y Yang, F Wang, YT Xiao, N Zhang, X Bian, Y Zhu, Y Yu, ...
Nature cell biology 23 (1), 87-98, 2021
3002021
Refined DNase-seq protocol and data analysis reveals intrinsic bias in transcription factor footprint identification
HH He, CA Meyer, SS Hu, MW Chen, C Zang, Y Liu, PK Rao, T Fei, H Xu, ...
Nature methods 11 (1), 73-78, 2014
2742014
The DNA methylation landscape of advanced prostate cancer
SG Zhao, WS Chen, H Li, A Foye, M Zhang, M Sjöström, R Aggarwal, ...
Nature genetics 52 (8), 778-789, 2020
2672020
Differentiation-specific histone modifications reveal dynamic chromatin interactions and partners for the intestinal transcription factor CDX2
MP Verzi, H Shin, HH He, R Sulahian, CA Meyer, RK Montgomery, ...
Developmental cell 19 (5), 713-726, 2010
2372010
Modulation of long noncoding RNAs by risk SNPs underlying genetic predispositions to prostate cancer
H Guo, M Ahmed, F Zhang, CQ Yao, SD Li, Y Liang, J Hua, F Soares, ...
Nature genetics 48 (10), 1142-1150, 2016
2362016
RNA N6-methyladenosine methyltransferase METTL3 facilitates colorectal cancer by activating the m6A-GLUT1-mTORC1 axis and is a therapeutic target
H Chen, S Gao, W Liu, CC Wong, J Wu, J Wu, D Liu, H Gou, W Kang, ...
Gastroenterology 160 (4), 1284-1300. e16, 2021
2232021
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