| Effect of prolonged differentiation on functional maturation of human pluripotent stem cell-derived neuronal cultures T Paavilainen, A Pelkonen, MEL Mäkinen, M Peltola, H Huhtala, D Fayuk, ... Stem Cell Research 27, 151-161, 2018 | 61 | 2018 |
| Laminin α5 substrates promote survival, network formation and functional development of human pluripotent stem cell-derived neurons in vitro A Hyysalo, M Ristola, MEL Mäkinen, S Häyrynen, M Nykter, S Narkilahti Stem cell research 24, 118-127, 2017 | 57 | 2017 |
| A microtiter plate assay for N-acetyl-β-D-glucosaminidase using a fluorogenic substrate S Linko-Löppönen, M Mäkinen Analytical biochemistry 148 (1), 50-53, 1985 | 44 | 1985 |
| Monitoring of amino acids and antibody N-glycosylation in high cell density perfusion culture based on Raman spectroscopy H Schwarz, ME Mäkinen, A Castan, V Chotteau Biochemical Engineering Journal 182, 108426, 2022 | 27 | 2022 |
| GABA and gap junctions in the development of synchronized activity in human pluripotent stem cell-derived neural networks MEL Mäkinen, L Ylä-Outinen, S Narkilahti Frontiers in cellular neuroscience 12, 56, 2018 | 24 | 2018 |
| Novel column generation-based optimization approach for poly-pathway kinetic model applied to CHO cell culture E Hagrot, HÆ Oddsdóttir, M Mäkinen, A Forsgren, V Chotteau Metabolic engineering communications 8, e00083, 2019 | 22 | 2019 |
| Optimised PDMS tunnel devices on MEAs increase the probability of detecting electrical activity from human stem cell-derived neuronal networks M Toivanen, A Pelkonen, M Mäkinen, L Ylä-Outinen, L Sukki, P Kallio, ... Frontiers in neuroscience 11, 606, 2017 | 16 | 2017 |
| Fluorescent probes as a tool for cell population tracking in spontaneously active neural networks derived from human pluripotent stem cells M Mäkinen, T Joki, L Ylä-Outinen, H Skottman, S Narkilahti, R Äänismaa Journal of Neuroscience Methods 215 (1), 88-96, 2013 | 15 | 2013 |
| Generic chemometric models for metabolite concentration prediction based on Raman spectra A Yousefi-Darani, O Paquet-Durand, A Von Wrochem, J Classen, ... Sensors 22 (15), 5581, 2022 | 11 | 2022 |
| Joint analysis of extracellular spike waveforms and neuronal network bursts FE Kapucu, MEL Mäkinen, JMA Tanskanen, L Ylä-Outinen, S Narkilahti, ... Journal of Neuroscience Methods 259, 143-155, 2016 | 11 | 2016 |
| Capillary and microchip electrophoresis method development for amino acid monitoring during biopharmaceutical cultivation S Mikkonen, L Josefsson, MEL Mäkinen, V Chotteau, Å Emmer Biotechnology Journal 17 (8), 2100325, 2022 | 6 | 2022 |
| Knowing more from less: miniaturization of ligand-binding assays and electrophoresis as new paradigms for at-line monitoring and control of mammalian cell bioprocesses IF Pinto, S Mikkonen, L Josefsson, MEL Mäkinen, RRG Soares, A Russom, ... Current Opinion in Biotechnology 71, 55-64, 2021 | 6 | 2021 |
| Practical data-driven modeling and robust predictive control of mammalian cell fed-batch process L Dewasme, M Mäkinen, V Chotteau Computers & Chemical Engineering 171, 108164, 2023 | 2 | 2023 |
| Mathematical modelling of cell culture processes V Chotteau, E Hagrot, L Zhang, MEL Mäkinen Cell Culture Engineering and Technology: In appreciation to Professor …, 2022 | 2 | 2022 |
| Continuous Bioprocessing for Upstream Process: Perfusion Process V Chotteau, H Schwarz, M Mäkinen Biopharmaceutical Manufacturing: Progress, Trends and Challenges, 113-158, 2024 | 1 | 2024 |
| Scale‐down of CHO cell cultivation from shake flasks based on oxygen mass transfer allows application of parallelized, non‐invasive, and time‐resolved monitoring of the oxygen … N Ihling, C Berg, R Paul, LP Munkler, MEL Mäkinen, V Chotteau, J Büchs Biotechnology Journal 18 (11), 2300053, 2023 | 1 | 2023 |
| A cell culturing platform, a cell culture system, and a method for modeling myelination in vitro S Narkilahti, YLÄO Laura, L Sukki, T RYYNÄNEN, M MÄKINEN, ... | 1 | 2015 |
| Multivariable robust tube-based nonlinear model predictive control of mammalian cell cultures L Dewasme, M Mäkinen, V Chotteau Computers & Chemical Engineering 183, 108592, 2024 | | 2024 |
| Raman spectroscopy for on-line monitoring of amino acid concentrations and antibody N-glycosylation in high cell density perfusion process V Chotteau, H Schwarz, M Mäkinen, A Castan | | 2023 |
| Toolbox for efficient development of high cell density perfusion process, integrated with continuous DSP N Arnold Brechmann, H Schwarz, MEL Mäkinen, V Chotteau, ... | | 2023 |
