The BCKDH kinase and phosphatase integrate BCAA and lipid metabolism via regulation of ATP-citrate lyase PJ White, RW McGarrah, PA Grimsrud, SC Tso, WH Yang, JM Haldeman, ... Cell metabolism 27 (6), 1281-1293. e7, 2018 | 256 | 2018 |
β Cell tone is defined by proglucagon peptides through cAMP signaling ME Capozzi, B Svendsen, SE Encisco, SL Lewandowski, MD Martin, ... JCI insight 4 (5), 2019 | 207 | 2019 |
Pdx-1 activates islet α-and β-cell proliferation via a mechanism regulated by transient receptor potential cation channels 3 and 6 and extracellular signal-regulated kinases 1 … HL Hayes, LG Moss, JC Schisler, JM Haldeman, Z Zhang, PB Rosenberg, ... Molecular and cellular biology 33 (20), 4017-4029, 2013 | 60 | 2013 |
Chromogranin B regulates early-stage insulin granule trafficking from the Golgi in pancreatic islet β-cells SC Bearrows, CJ Bauchle, MK Becker, JM Haldeman, S Swaminathan, ... Journal of cell science 132 (13), jcs231373, 2019 | 47 | 2019 |
Delayed apoptosis allows islet β-cells to implement an autophagic mechanism to promote cell survival HL Hayes, BS Peterson, JM Haldeman, CB Newgard, HE Hohmeier, ... PloS one 12 (2), e0172567, 2017 | 42 | 2017 |
A critical role for CRM1 in regulating HOXA gene transcription in CALM-AF10 leukemias AE Conway, JM Haldeman, DS Wechsler, CP Lavau Leukemia 29 (2), 423-432, 2015 | 35 | 2015 |
Creation of versatile cloning platforms for transgene expression and dCas9-based epigenome editing JM Haldeman, AE Conway, ME Arlotto, DH Slentz, DM Muoio, TC Becker, ... Nucleic acids research 47 (4), e23-e23, 2019 | 27 | 2019 |
Control of voltage-gated potassium channel Kv2. 2 expression by pyruvate-isocitrate cycling regulates glucose-stimulated insulin secretion MV Jensen, JM Haldeman, H Zhang, D Lu, MO Huising, WW Vale, ... Journal of Biological Chemistry 288 (32), 23128-23140, 2013 | 25 | 2013 |
A Pdx-1-regulated soluble factor activates rat and human islet cell proliferation HL Hayes, L Zhang, TC Becker, JM Haldeman, SB Stephens, M Arlotto, ... Molecular and cellular biology 36 (23), 2918-2930, 2016 | 21 | 2016 |
HGFAC is a ChREBP-regulated hepatokine that enhances glucose and lipid homeostasis MAH Ashot Sargsyan, Ludivine Doridot, Sarah A Hannou, Wenxin Tong, Harini ... JCI insight 8 (1), 2023 | 10* | 2023 |
Physiological mechanisms of sustained fumagillin-induced weight loss J An, L Wang, ML Patnode, VK Ridaura, JM Haldeman, RD Stevens, ... JCI insight 3 (5), 2018 | 8 | 2018 |
β cell tone is defined by proglucagon peptides through cAMP signaling. JCI Insight 4 (5): e126742 ME Capozzi, B Svendsen, SE Encisco, SL Lewandowski, MD Martin, ... | 6 | 2019 |
Transcriptional activation of the Myc gene by glucose in β-cells requires a ChREBP-dependent 3-D chromatin interaction between the Myc and Pvt1 genes LS Katz, G Brill, P Wang, L Lambertini, P Zhang, JM Haldeman, H Liu, ... Molecular Metabolism 79, 101848, 2024 | | 2024 |
1728-P: Transcriptional Activation of Myc by Glucose Requires Recruitment of ChREBP to the Pvt1 Promoter Regulating Proliferation in ß-Cells LS KATZ, P WANG, G BRILL, P ZHANG, J HALDEMAN, CB NEWGARD, ... Diabetes 72 (Supplement_1), 2023 | | 2023 |
Integration of BCAA and Lipid Metabolism by the BCKDH Kinase and Phosphatase PJ White, RW MCGARRAH, PA Grimsrud, WH Yang, GF Zhang, ... Diabetes 67 (Supplement_1), 2018 | | 2018 |
Creation of Versatile Cloning Platforms for Transgene Expression and Epigenome Editing and Their Application to Pancreatic Islet Biology JM Haldeman Duke University, 2018 | | 2018 |
Human, Mouse, and Rat Multitissue Integrative Chromatin State and eRNA Maps Reveal Conserved Stretch Enhancer Landscapes at Diabetes and Related Trait Loci A Varshney, J Haldeman, M Erdos, R Albanus, P Orchard, R Kursawe, ... DIABETES 66, A48-A49, 2017 | | 2017 |
Characterization of Pdx-1 Induced Soluble Factors that Stimulate Beta-Cell Proliferation L Zhang, H Hayes, J Haldeman, S Stephens, DH Lu, M Arlotto, TC Becker, ... American Diabetes Association Scientific Sessions 65, A529-A529, 2016 | | 2016 |
Pdx-1 activates islet α-and β-cell proliferation via a TRPC3/6-and ERK 1/2-regulated mechanism 2 HL Hayes, LG Moss, JC Schisler, JM Haldeman, Z Zhang, PB Rosenberg, ... | | 2013 |