Managing, analysing, and integrating big data in medical bioinformatics: open problems and future perspectives I Merelli, H Pérez-Sánchez, S Gesing, D D’Agostino BioMed research international 2014, 2014 | 160 | 2014 |
A multilevel data integration resource for breast cancer study E Mosca, R Alfieri, I Merelli, F Viti, A Calabria, L Milanesi BMC systems biology 4 (1), 1-11, 2010 | 94 | 2010 |
Grid-Enabled High-Throughput In Silico Screening Against Influenza A Neuraminidase HC Lee, J Salzemann, N Jacq, HY Chen, LY Ho, I Merelli, L Milanesi, ... IEEE transactions on nanobioscience 5 (4), 288-295, 2006 | 71 | 2006 |
Precise gene editing preserves hematopoietic stem cell function following transient p53-mediated DNA damage response G Schiroli, A Conti, S Ferrari, L Della Volpe, A Jacob, L Albano, S Beretta, ... Cell stem cell 24 (4), 551-565. e8, 2019 | 69 | 2019 |
Molecular mechanism of allosteric communication in Hsp70 revealed by molecular dynamics simulations F Chiappori, I Merelli, G Colombo, L Milanesi, G Morra PLoS Comput Biol 8 (12), e1002844, 2012 | 53 | 2012 |
RSSsite: a reference database and prediction tool for the identification of cryptic Recombination Signal Sequences in human and murine genomes I Merelli, A Guffanti, M Fabbri, A Cocito, L Furia, U Grazini, RJ Bonnal, ... Nucleic acids research 38 (suppl_2), W262-W267, 2010 | 47 | 2010 |
Virtual screening on large scale grids N Jacq, V Breton, HY Chen, LY Ho, M Hofmann, V Kasam, HC Lee, ... Parallel Computing 33 (4-5), 289-301, 2007 | 45 | 2007 |
HIV-1-mediated insertional activation of STAT5B and BACH2 trigger viral reservoir in T regulatory cells D Cesana, FRS de Sio, L Rudilosso, P Gallina, A Calabria, S Beretta, ... Nature communications 8 (1), 1-11, 2017 | 43 | 2017 |
Version VI of the ESTree db: an improved tool for peach transcriptome analysis B Lazzari, A Caprera, A Vecchietti, I Merelli, F Barale, L Milanesi, A Stella, ... BMC bioinformatics 9 (2), 1-6, 2008 | 36 | 2008 |
DnaK as antibiotic target: hot spot residues analysis for differential inhibition of the bacterial protein in comparison with the human HSP70 F Chiappori, M Fumian, L Milanesi, I Merelli PloS one 10 (4), e0124563, 2015 | 30 | 2015 |
An atomistic view of Hsp70 allosteric crosstalk: from the nucleotide to the substrate binding domain and back F Chiappori, I Merelli, L Milanesi, G Colombo, G Morra Scientific reports 6 (1), 1-14, 2016 | 29 | 2016 |
NuChart: an R package to study gene spatial neighbourhoods with multi-omics annotations I Merelli, P Liò, L Milanesi PLoS One 8 (9), e75146, 2013 | 29 | 2013 |
A data integration approach for cell cycle analysis oriented to model simulation in systems biology R Alfieri, I Merelli, E Mosca, L Milanesi BMC systems biology 1 (1), 1-12, 2007 | 28 | 2007 |
Cloud infrastructures for in silico drug discovery: economic and practical aspects D D'Agostino, A Clematis, A Quarati, D Cesini, F Chiappori, L Milanesi, ... BioMed Research International 2013, 2013 | 26 | 2013 |
In silico saturation mutagenesis and docking screening for the analysis of protein-ligand interaction: the Endothelial Protein C Receptor case study F Chiappori, P D'Ursi, I Merelli, L Milanesi, E Rovida BMC bioinformatics 10 (12), 1-8, 2009 | 26 | 2009 |
Virtual screening pipeline and ligand modelling for H5N1 neuraminidase P D’Ursi, F Chiappori, I Merelli, P Cozzi, E Rovida, L Milanesi Biochemical and biophysical research communications 383 (4), 445-449, 2009 | 25 | 2009 |
SNPranker 2.0: a gene-centric data mining tool for diseases associated SNP prioritization in GWAS I Merelli, A Calabria, P Cozzi, F Viti, E Mosca, L Milanesi BMC bioinformatics 14 (1), 1-12, 2013 | 23 | 2013 |
Structural thermal adaptation of β‐tubulins from the Antarctic psychrophilic protozoan Euplotes focardii F Chiappori, S Pucciarelli, I Merelli, P Ballarini, C Miceli, L Milanesi Proteins: Structure, Function, and Bioinformatics 80 (4), 1154-1166, 2012 | 23 | 2012 |
Image-based surface matching algorithm oriented to structural biology I Merelli, P Cozzi, D D'Agostino, A Clematis, L Milanesi IEEE/ACM Transactions on Computational Biology and Bioinformatics 8 (4 …, 2010 | 23 | 2010 |
Ontology-based, Tissue MicroArray oriented, image centered tissue bank F Viti, I Merelli, A Caprera, B Lazzari, A Stella, L Milanesi BMC bioinformatics 9 (4), 1-9, 2008 | 22 | 2008 |