| Macrocycles are great cycles: applications, opportunities, and challenges of synthetic macrocycles in drug discovery E Marsault, ML Peterson Journal of medicinal chemistry 54 (7), 1961-2004, 2011 | 897 | 2011 |
| The transannular Diels–Alder strategy: applications to total synthesis E Marsault, A Toró, P Nowak, P Deslongchamps Tetrahedron 57 (20), 4243-4260, 2001 | 162 | 2001 |
| A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic T Shapira, IA Monreal, SP Dion, DW Buchholz, B Imbiakha, AD Olmstead, ... Nature 605 (7909), 340-348, 2022 | 136 | 2022 |
| Discovery and structure–activity relationship of a bioactive fragment of ELABELA that modulates vascular and cardiac functions A Murza, X Sainsily, D Coquerel, J Côté, P Marx, É Besserer-Offroy, ... Journal of medicinal chemistry 59 (7), 2962-2972, 2016 | 132 | 2016 |
| Tomatidine acts in synergy with aminoglycoside antibiotics against multiresistant Staphylococcus aureus and prevents virulence gene expression G Mitchell, M Lafrance, S Boulanger, DL Séguin, I Guay, M Gattuso, ... Journal of antimicrobial chemotherapy 67 (3), 559-568, 2012 | 121 | 2012 |
| Conjugation of a brain-penetrant peptide with neurotensin provides antinociceptive properties M Demeule, N Beaudet, A Régina, É Besserer-Offroy, A Murza, ... The Journal of clinical investigation 124 (3), 1199-1213, 2014 | 119 | 2014 |
| Elucidation of the structure–activity relationships of apelin: influence of unnatural amino acids on binding, signaling, and plasma stability A Murza, A Parent, E Besserer‐Offroy, H Tremblay, F Karadereye, ... ChemMedChem 7 (2), 318-325, 2012 | 112 | 2012 |
| Diversity-oriented synthesis: basics and applications in organic synthesis, drug discovery, and chemical biology A Trabocchi John Wiley & Sons, 2013 | 97* | 2013 |
| Matriptase proteolytically activates influenza virus and promotes multicycle replication in the human airway epithelium A Beaulieu, É Gravel, A Cloutier, I Marois, É Colombo, A Désilets, ... Journal of virology 87 (8), 4237-4251, 2013 | 93 | 2013 |
| Macrocyclic cell penetrating peptides: A study of structure-penetration properties H Traboulsi, H Larkin, MA Bonin, L Volkov, CL Lavoie, É Marsault Bioconjugate chemistry 26 (3), 405-411, 2015 | 88 | 2015 |
| Optimization of the potency and pharmacokinetic properties of a macrocyclic ghrelin receptor agonist (Part I): development of ulimorelin (TZP-101) from hit to clinic HR Hoveyda, E Marsault, R Gagnon, AP Mathieu, M Vézina, A Landry, ... Journal of medicinal chemistry 54 (24), 8305-8320, 2011 | 82 | 2011 |
| Tomatidine inhibits replication of Staphylococcus aureus small-colony variants in cystic fibrosis airway epithelial cells G Mitchell, M Gattuso, G Grondin, É Marsault, K Bouarab, F Malouin Antimicrobial agents and chemotherapy 55 (5), 1937-1945, 2011 | 82 | 2011 |
| Preparation of phosphorothioate and boranophosphate oligomers G Just, Z Xin, E Marsault, Y Jin, J Wang, M Manoharan US Patent 6,160,109, 2000 | 79 | 2000 |
| Stability and degradation patterns of chemically modified analogs of apelin‐13 in plasma and cerebrospinal fluid A Murza, K Belleville, JM Longpré, P Sarret, É Marsault Peptide Science 102 (4), 297-303, 2014 | 77 | 2014 |
| Discovery of a new class of macrocyclic antagonists to the human motilin receptor E Marsault, HR Hoveyda, ML Peterson, C Saint-Louis, A Landry, ... Journal of medicinal chemistry 49 (24), 7190-7197, 2006 | 76 | 2006 |
| Design and synthesis of potent, selective inhibitors of matriptase É Colombo, A Désilets, D Duchêne, F Chagnon, R Najmanovich, R Leduc, ... ACS Medicinal Chemistry Letters 3 (7), 530-534, 2012 | 75 | 2012 |
| Tomatidine is a lead antibiotic molecule that targets Staphylococcus aureus ATP synthase subunit C M Lamontagne Boulet, C Isabelle, I Guay, E Brouillette, JP Langlois, ... Antimicrobial agents and chemotherapy 62 (6), 10.1128/aac. 02197-17, 2018 | 70 | 2018 |
| Targeting matriptase in breast cancer abrogates tumour progression via impairment of stromal-epithelial growth factor signalling GL Zoratti, LM Tanabe, FA Varela, AS Murray, C Bergum, É Colombo, ... Nature communications 6 (1), 6776, 2015 | 67 | 2015 |
| The apelinergic system: a perspective on challenges and opportunities in cardiovascular and metabolic disorders E Marsault, C Llorens‐Cortes, X Iturrioz, HJ Chun, O Lesur, GY Oudit, ... Annals of the New York Academy of Sciences 1455 (1), 12-33, 2019 | 64 | 2019 |
| The signaling signature of the neurotensin type 1 receptor with endogenous ligands É Besserer-Offroy, RL Brouillette, S Lavenus, U Froehlich, A Brumwell, ... European journal of pharmacology 805, 1-13, 2017 | 63 | 2017 |
