Chaitan Khosla
Chaitan Khosla
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Zitiert von
Zitiert von
Structural basis for gluten intolerance in celiac sprue
L Shan, Ø Molberg, I Parrot, F Hausch, F Filiz, GM Gray, LM Sollid, ...
Science 297 (5590), 2275-2279, 2002
A new enzyme superfamily—the phosphopantetheinyl transferases
RH Lambalot, AM Gehring, RS Flugel, P Zuber, M LaCelle, MA Marahiel, ...
Chemistry & biology 3 (11), 923-936, 1996
Biosynthesis of complex polyketides in a metabolically engineered strain of E. coli
BA Pfeifer, SJ Admiraal, H Gramajo, DE Cane, C Khosla
Science 291 (5509), 1790-1792, 2001
Harnessing the biosynthetic code: combinations, permutations, and mutations
DE Cane, CT Walsh, C Khosla
Science 282 (5386), 63-68, 1998
Engineered biosynthesis of novel polyketides
R McDaniel, S Ebert-Khosla, DA Hopwood, C Khosla
Science 262 (5139), 1546-1550, 1993
Cloning and heterologous expression of the epothilone gene cluster
L Tang, S Shah, L Chung, J Carney, L Katz, C Khosla, B Julien
Science 287 (5453), 640-642, 2000
Structural basis for HLA-DQ2-mediated presentation of gluten epitopes in celiac disease
CY Kim, H Quarsten, E Bergseng, C Khosla, LM Sollid
Proceedings of the National Academy of Sciences 101 (12), 4175-4179, 2004
Transglutaminase 2 undergoes a large conformational change upon activation
DM Pinkas, P Strop, AT Brunger, C Khosla
PLoS biology 5 (12), e327, 2007
Intestinal digestive resistance of immunodominant gliadin peptides
F Hausch, L Shan, NA Santiago, GM Gray, C Khosla
American Journal of Physiology-Gastrointestinal and Liver Physiology 283 (4 …, 2002
Overproduction of free fatty acids in E. coli: implications for biodiesel production
X Lu, H Vora, C Khosla
Metabolic engineering 10 (6), 333-339, 2008
Tolerance and specificity of polyketide synthases
C Khosla, RS Gokhale, JR Jacobsen, DE Cane
Annual review of biochemistry 68 (1), 219-253, 1999
Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease
R Bouziat, R Hinterleitner, JJ Brown, JE Stencel-Baerenwald, M Ikizler, ...
Science 356 (6333), 44-50, 2017
Dissecting and exploiting intermodular communication in polyketide synthases
RS Gokhale, SY Tsuji, DE Cane, C Khosla
Science 284 (5413), 482-485, 1999
Precursor-directed biosynthesis of erythromycin analogs by an engineered polyketide synthase
JR Jacobsen, CR Hutchinson, DE Cane, C Khosla
Science 277 (5324), 367-369, 1997
Nonproteinogenic amino acid building blocks for nonribosomal peptide and hybrid polyketide scaffolds
CT Walsh, RV O'Brien, C Khosla
Angewandte Chemie International Edition 52 (28), 7098-7124, 2013
Biosynthesis of polyketides in heterologous hosts
BA Pfeifer, C Khosla
Microbiology and Molecular Biology Reviews 65 (1), 106-118, 2001
Rational design of aromatic polyketide natural products by recombinant assembly of enzymatic subunits
R McDaniel, S Ebert-Khosla, DA Hopwood, C Khosla
Nature 375 (6532), 549-554, 1995
Identification and analysis of multivalent proteolytically resistant peptides from gluten: implications for celiac sprue
L Shan, SW Qiao, H Arentz-Hansen, Ø Molberg, GM Gray, LM Sollid, ...
Journal of proteome research 4 (5), 1732-1741, 2005
Structure and mechanism of the 6-deoxyerythronolide B synthase
C Khosla, Y Tang, AY Chen, NA Schnarr, DE Cane
Annu. Rev. Biochem. 76, 195-221, 2007
Engineered biosynthesis of a complete macrolactone in a heterologous host
CM Kao, L Katz, C Khosla
Science 265 (5171), 509-512, 1994
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