| Antibody tumor penetration: transport opposed by systemic and antigen-mediated clearance GM Thurber, MM Schmidt, KD Wittrup Advanced drug delivery reviews 60 (12), 1421-1434, 2008 | 663 | 2008 |
| 18F Labeled Nanoparticles for in Vivo PET-CT Imaging NK Devaraj, EJ Keliher, GM Thurber, M Nahrendorf, R Weissleder Bioconjugate chemistry 20 (2), 397-401, 2009 | 313 | 2009 |
| Factors determining antibody distribution in tumors GM Thurber, MM Schmidt, KD Wittrup Trends in pharmacological sciences 29 (2), 57-61, 2008 | 255 | 2008 |
| Reactive polymer enables efficient in vivo bioorthogonal chemistry NK Devaraj, GM Thurber, EJ Keliher, B Marinelli, R Weissleder Proceedings of the National Academy of Sciences 109 (13), 4762-4767, 2012 | 213 | 2012 |
| Single-cell and subcellular pharmacokinetic imaging allows insight into drug action in vivo GM Thurber, KS Yang, T Reiner, RH Kohler, P Sorger, T Mitchison, ... Nature communications 4 (1), 1504, 2013 | 211 | 2013 |
| Practical theoretic guidance for the design of tumor-targeting agents KD Wittrup, GM Thurber, MM Schmidt, JJ Rhoden Methods in enzymology 503, 255-268, 2012 | 200 | 2012 |
| Hybrid in vivo FMT-CT imaging of protease activity in atherosclerosis with customized nanosensors M Nahrendorf, P Waterman, G Thurber, K Groves, M Rajopadhye, ... Arteriosclerosis, thrombosis, and vascular biology 29 (10), 1444-1451, 2009 | 193 | 2009 |
| Theoretic criteria for antibody penetration into solid tumors and micrometastases GM Thurber, SC Zajic, KD Wittrup Journal of Nuclear Medicine 48 (6), 995-999, 2007 | 164 | 2007 |
| A systems approach for tumor pharmacokinetics GM Thurber, R Weissleder PloS one 6 (9), e24696, 2011 | 131 | 2011 |
| Accurate measurement of pancreatic islet β-cell mass using a second-generation fluorescent exendin-4 analog T Reiner, G Thurber, J Gaglia, C Vinegoni, CW Liew, R Upadhyay, ... Proceedings of the National Academy of Sciences 108 (31), 12815-12820, 2011 | 131 | 2011 |
| Quantitative spatiotemporal analysis of antibody fragment diffusion and endocytic consumption in tumor spheroids GM Thurber, KD Wittrup Cancer research 68 (9), 3334-3341, 2008 | 111 | 2008 |
| A mechanistic compartmental model for total antibody uptake in tumors GM Thurber, KD Wittrup Journal of theoretical biology 314, 57-68, 2012 | 110 | 2012 |
| Kinetics of anti-carcinoembryonic antigen antibody internalization: effects of affinity, bivalency, and stability MM Schmidt, GM Thurber, KD Wittrup Cancer immunology, immunotherapy 57, 1879-1890, 2008 | 108 | 2008 |
| Population dynamics of islet-infiltrating cells in autoimmune diabetes AM Magnuson, GM Thurber, RH Kohler, R Weissleder, D Mathis, ... Proceedings of the National Academy of Sciences 112 (5), 1511-1516, 2015 | 107 | 2015 |
| Multiscale modeling of antibody-drug conjugates: connecting tissue and cellular distribution to whole animal pharmacokinetics and potential implications for efficacy C Cilliers, H Guo, J Liao, N Christodolu, GM Thurber The AAPS journal 18, 1117-1130, 2016 | 102 | 2016 |
| Tracking antibody distribution with near-infrared fluorescent dyes: impact of dye structure and degree of labeling on plasma clearance C Cilliers, I Nessler, N Christodolu, GM Thurber Molecular pharmaceutics 14 (5), 1623-1633, 2017 | 96 | 2017 |
| Improved tumor penetration and single-cell targeting of antibody–drug conjugates increases anticancer efficacy and host survival C Cilliers, B Menezes, I Nessler, J Linderman, GM Thurber Cancer research 78 (3), 758-768, 2018 | 94 | 2018 |
| Increased Tumor Penetration of Single-Domain Antibody–Drug Conjugates Improves In Vivo Efficacy in Prostate Cancer Models I Nessler, E Khera, S Vance, A Kopp, Q Qiu, TA Keating, AO Abu-Yousif, ... Cancer research 80 (6), 1268-1278, 2020 | 78 | 2020 |
| Tumor drug penetration measurements could be the neglected piece of the personalized cancer treatment puzzle IH Bartelink, EF Jones, SK Shahidi‐Latham, PRE Lee, Y Zheng, P Vicini, ... Clinical Pharmacology & Therapeutics 106 (1), 148-163, 2019 | 70 | 2019 |
| Co-administered antibody improves penetration of antibody–dye conjugate into human cancers with implications for antibody–drug conjugates G Lu, N Nishio, NS van den Berg, BA Martin, S Fakurnejad, S van Keulen, ... Nature Communications 11 (1), 5667, 2020 | 67 | 2020 |
