| Membrane curvature induction and tubulation are common features of synucleins and apolipoproteins J Varkey, JM Isas, N Mizuno, MB Jensen, VK Bhatia, CC Jao, J Petrlova, ... Journal of Biological Chemistry 285 (42), 32486-32493, 2010 | 394 | 2010 |
| Pericyte degeneration causes white matter dysfunction in the mouse central nervous system A Montagne, AM Nikolakopoulou, Z Zhao, AP Sagare, G Si, D Lazic, ... Nature medicine 24 (3), 326-337, 2018 | 337 | 2018 |
| Remodeling of lipid vesicles into cylindrical micelles by α-synuclein in an extended α-helical conformation N Mizuno, J Varkey, NC Kegulian, BG Hegde, N Cheng, R Langen, ... Journal of Biological Chemistry 287 (35), 29301-29311, 2012 | 132 | 2012 |
| Semisynthetic, site-specific ubiquitin modification of α-synuclein reveals differential effects on aggregation F Meier, T Abeywardana, A Dhall, NP Marotta, J Varkey, R Langen, ... Journal of the American Chemical Society 134 (12), 5468-5471, 2012 | 122 | 2012 |
| Antibacterial activity of human neutrophil defensin HNP-1 analogs without cysteines J Varkey, R Nagaraj Antimicrobial agents and chemotherapy 49 (11), 4561-4566, 2005 | 116 | 2005 |
| Rational design of potent domain antibody inhibitors of amyloid fibril assembly ARA Ladiwala, M Bhattacharya, JM Perchiacca, P Cao, DP Raleigh, ... Proceedings of the National Academy of Sciences 109 (49), 19965-19970, 2012 | 112 | 2012 |
| Nonaggregated α-synuclein influences SNARE-dependent vesicle docking via membrane binding Y Lai, S Kim, J Varkey, X Lou, JK Song, J Diao, R Langen, YK Shin Biochemistry 53 (24), 3889-3896, 2014 | 101 | 2014 |
| Hydration dynamics as an intrinsic ruler for refining protein structure at lipid membrane interfaces CY Cheng, J Varkey, MR Ambroso, R Langen, S Han Proceedings of the National Academy of Sciences 110 (42), 16838-16843, 2013 | 89 | 2013 |
| α-Synuclein oligomers with broken helical conformation form lipoprotein nanoparticles J Varkey, N Mizuno, BG Hegde, N Cheng, AC Steven, R Langen Journal of Biological Chemistry 288 (24), 17620-17630, 2013 | 86 | 2013 |
| α-Synuclein amyloid fibrils with two entwined, asymmetrically associated protofibrils AD Dearborn, JS Wall, N Cheng, JB Heymann, AV Kajava, J Varkey, ... Journal of Biological Chemistry 291 (5), 2310-2318, 2016 | 63 | 2016 |
| Gene co-expression network analysis for identifying genetic markers in Parkinson's disease-a three-way comparative approach G George, S Singh, SB Lokappa, J Varkey Genomics 111 (4), 819-830, 2019 | 49 | 2019 |
| Membranes as modulators of amyloid protein misfolding and target of toxicity A Rawat, R Langen, J Varkey Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (9), 1863-1875, 2018 | 42 | 2018 |
| E46K-like α-synuclein mutants increase lipid interactions and disrupt membrane selectivity M Rovere, AE Powers, H Jiang, JC Pitino, L Fonseca-Ornelas, DS Patel, ... Journal of Biological Chemistry 294 (25), 9799-9812, 2019 | 40 | 2019 |
| Antibacterial activity of linear peptides spanning the carboxy-terminal β-sheet domain of arthropod defensins J Varkey, S Singh, R Nagaraj Peptides 27 (11), 2614-2623, 2006 | 31 | 2006 |
| Early sodium dodecyl sulfate induced collapse of α-synuclein correlates with its amyloid formation S Basak, GVRK Prasad, J Varkey, K Chattopadhyay ACS chemical neuroscience 6 (2), 239-246, 2015 | 21 | 2015 |
| Construction of Parkinson's disease marker-based weighted protein-protein interaction network for prioritization of co-expressed genes G George, SV Parambath, SB Lokappa, J Varkey Gene 697, 67-77, 2019 | 19 | 2019 |
| Membrane remodeling by amyloidogenic and non-amyloidogenic proteins studied by EPR J Varkey, R Langen Journal of Magnetic Resonance 280, 127-139, 2017 | 12 | 2017 |
| An amphipathic alpha-helix domain from poliovirus 2C protein tubulate lipid vesicles J Varkey, J Zhang, J Kim, G George, G He, G Belov, R Langen, X Wang Viruses 12 (12), 1466, 2020 | 10 | 2020 |
| Structural Model of the Proline-Rich Domain of Huntingtin Exon-1 Fibrils ABS Alexander S. Falk, José M. Bravo-Arredondo, Jobin Varkey, Sayuri Pacheco ... Biophysical Journal 119 (10), 2019-2028, 2020 | 10 | 2020 |
| Fluorescent protein tagging promotes phase separation and alters the aggregation pathway of huntingtin exon-1 NK Pandey, J Varkey, A Ajayan, G George, J Chen, R Langen Journal of Biological Chemistry 300 (1), 2024 | 3 | 2024 |
J Mario isasUniversity Southern CaliforniaBestätigte E-Mail-Adresse bei usc.edu
