Mimicking the active site of protein disulfide-isomerase by substitution of proline 34 in Escherichia coli thioredoxin G Krause, J Lundström, JL Barea, CP de La Cuesta, A Holmgren Journal of Biological Chemistry 266 (15), 9494-9500, 1991 | 324 | 1991 |
miRNA deregulation by epigenetic silencing disrupts suppression of the oncogene PLAG1 in chronic lymphocytic leukemia CP Pallasch, M Patz, YJ Park, S Hagist, D Eggle, R Claus, ... Blood, The Journal of the American Society of Hematology 114 (15), 3255-3264, 2009 | 178 | 2009 |
Comparison of the in vitro effects of the anti‐CD20 antibodies rituximab and GA101 on chronic lymphocytic leukaemia cells M Patz, P Isaeva, N Forcob, B Müller, LP Frenzel, CM Wendtner, C Klein, ... British journal of haematology 152 (3), 295-306, 2011 | 174 | 2011 |
A Pro to His mutation in active site of thioredoxin increases its disulfide-isomerase activity 10-fold. New refolding systems for reduced or randomly oxidized ribonuclease. J Lundström, G Krause, A Holmgren Journal of Biological Chemistry 267 (13), 9047-9052, 1992 | 143 | 1992 |
The kinase inhibitor dasatinib induces apoptosis in chronic lymphocytic leukemia cells in vitro with preference for a subgroup of patients with unmutated IgVH genes A Veldurthy, M Patz, S Hagist, CP Pallasch, CM Wendtner, M Hallek, ... Blood, The Journal of the American Society of Hematology 112 (4), 1443-1452, 2008 | 133 | 2008 |
Substitution of the conserved tryptophan 31 in Escherichia coli thioredoxin by site-directed mutagenesis and structure-function analysis G Krause, A Holmgren Journal of Biological Chemistry 266 (7), 4056-4066, 1991 | 122 | 1991 |
Delayed development of chronic lymphocytic leukemia in the absence of macrophage migration inhibitory factor N Reinart, PH Nguyen, J Boucas, N Rosen, HM Kvasnicka, L Heukamp, ... Blood, The Journal of the American Society of Hematology 121 (5), 812-821, 2013 | 121 | 2013 |
Copanlisib for treatment of B-cell malignancies: the development of a PI3K inhibitor with considerable differences to idelalisib G Krause, F Hassenrück, M Hallek Drug Design, Development and Therapy 12, 2577-2590, 2018 | 69 | 2018 |
In vitro genotoxicity assay of sidestream smoke using a human bronchial epithelial cell line L Wolz, G Krause, G Scherer, M Aufderheide, U Mohr Food and chemical toxicology 40 (6), 845-850, 2002 | 56 | 2002 |
Efficacy of phosphatidylinositol‐3 kinase inhibitors with diverse isoform selectivity profiles for inhibiting the survival of chronic lymphocytic leukemia cells E Göckeritz, S Kerwien, M Baumann, M Wigger, V Vondey, L Neumann, ... International journal of cancer 137 (9), 2234-2242, 2015 | 49 | 2015 |
Total Synthesis of Indole‐Derived Allocolchicine Analogues Exhibiting Strong Apoptosis‐Inducing Activity N Sitnikov, J Velder, L Abodo, N Cuvelier, J Neudörfl, A Prokop, G Krause, ... Chemistry–A European Journal 18 (38), 12096-12102, 2012 | 42 | 2012 |
Assignment of the 15N NMR spectra of reduced and oxidized Escherichia coli thioredoxin K Chandrasekhar, G Krause, A Holmgren, HJ Dyson FEBS letters 284 (2), 178-183, 1991 | 41 | 1991 |
The comet assay with MCL-5 cells as an indicator of genotoxic treatment with chemicals and cigarette smoke condensate L Wolz, G Krause, G Scherer Alternatives to Laboratory Animals 30 (3), 331-339, 2002 | 34 | 2002 |
Action of novel CD37 antibodies on chronic lymphocytic leukemia cells G Krause, M Patz, P Isaeva, M Wigger, I Baki, V Vondey, S Kerwien, ... Leukemia 26 (3), 546-549, 2012 | 30 | 2012 |
Inhibition of IL-6-dependent growth of myeloma cells by an acidic peptide repressing the gp130-mediated activation of Src family kinases A Hausherr, R Tavares, M Schäffer, A Obermeier, C Miksch, O Mitina, ... Oncogene 26 (34), 4987-4998, 2007 | 29 | 2007 |
Motion of aromatic side chains, picosecond fluorescence, and internal energy transfer in Escherichia coli thioredoxin studied by site-directed mutagenesis, time-resolved … A Elofsson, R Rigler, L Nilsson, J Roslund, G Krause, A Holmgren Biochemistry 30 (40), 9648-9656, 1991 | 26 | 1991 |
Role of p21WAF1/CIP1 as an attenuator of both proliferative and drug-induced apoptotic signals in BCR-ABL-transformed hematopoietic cells K Forster, A Obermeier, O Mitina, N Simon, M Warmuth, G Krause, ... Annals of hematology 87, 183-193, 2008 | 23 | 2008 |
Sensitive detection of the natural killer cell-mediated cytotoxicity of anti-CD20 antibodies and its impairment by B cell receptor pathway inhibitors F Hassenrück, E Knödgen, E Göckeritz, SH Midda, V Vondey, L Neumann, ... Biomed Res Int, 2018 | 21 | 2018 |
Transcripts encoding three types of guanylyl-cyclase-coupled trans-membrane receptors in inner ear tissues of guinea pigs G Krause, AMM zum Gottesberge, G Wolfram, R Gerzer Hearing research 110 (1-2), 95-106, 1997 | 19 | 1997 |
Src family tyrosine kinases phosphorylate Flt3 on juxtamembrane tyrosines and interfere with receptor maturation in a kinase-dependent manner O Mitina, M Warmuth, G Krause, M Hallek, A Obermeier Annals of Hematology 86, 777-785, 2007 | 17 | 2007 |