| Dominant negative mutations in human PPARγ associated with severe insulin resistance, diabetes mellitus and hypertension I Barroso, M Gurnell, VEF Crowley, M Agostini, JW Schwabe, MA Soos, ... Nature 402 (6764), 880-883, 1999 | 1769 | 1999 |
| The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: how receptors discriminate between their response elements JWR Schwabe, L Chapman, JT Finch, D Rhodes Cell 75 (3), 567-578, 1993 | 992 | 1993 |
| Zinc fingers A Klug, JWR Schwabe The FASEB journal 9 (8), 597-604, 1995 | 926 | 1995 |
| Solution structure of the DMA-binding domain of the oestrogen receptor JWR Schwabe, D Neuhaus, D Rhodes Nature 348 (6300), 458-461, 1990 | 590 | 1990 |
| Mechanism of corepressor binding and release from nuclear hormone receptors L Nagy, HY Kao, JD Love, C Li, E Banayo, JT Gooch, V Krishna, ... Genes & development 13 (24), 3209-3216, 1999 | 521 | 1999 |
| Structural basis for the activation of PPARγ by oxidized fatty acids T Itoh, L Fairall, K Amin, Y Inaba, A Szanto, BL Balint, L Nagy, ... Nature structural & molecular biology 15 (9), 924-931, 2008 | 513 | 2008 |
| Structure of HDAC3 bound to co-repressor and inositol tetraphosphate PJ Watson, L Fairall, GM Santos, JWR Schwabe Nature 481 (7381), 335-340, 2012 | 496 | 2012 |
| Mechanism of the nuclear receptor molecular switch L Nagy, JWR Schwabe Trends in biochemical sciences 29 (6), 317-324, 2004 | 487 | 2004 |
| STAT6 transcription factor is a facilitator of the nuclear receptor PPARγ-regulated gene expression in macrophages and dendritic cells A Szanto, BL Balint, ZS Nagy, E Barta, B Dezso, A Pap, L Szeles, ... Immunity 33 (5), 699-712, 2010 | 473 | 2010 |
| The crystal structure of a two zinc-finger peptide reveals an extension to the rules for zinc-finger/DNA recognition L Fairall, JWR Schwabe, L Chapman, JT Finch, D Rhodes Nature 366 (6454), 483-487, 1993 | 448 | 1993 |
| A mutation in the thyroid hormone receptor alpha gene E Bochukova, N Schoenmakers, M Agostini, E Schoenmakers, ... New England Journal of Medicine 366 (3), 243-249, 2012 | 416 | 2012 |
| A death effector domain chain DISC model reveals a crucial role for caspase-8 chain assembly in mediating apoptotic cell death LS Dickens, RS Boyd, R Jukes-Jones, MA Hughes, GL Robinson, ... Molecular cell 47 (2), 291-305, 2012 | 392 | 2012 |
| Class I HDACs share a common mechanism of regulation by inositol phosphates CJ Millard, PJ Watson, I Celardo, Y Gordiyenko, SM Cowley, ... Molecular cell 51 (1), 57-67, 2013 | 382 | 2013 |
| A dominant-negative peroxisome proliferator-activated receptor γ (PPARγ) mutant is a constitutive repressor and inhibits PPARγ-mediated adipogenesis M Gurnell, JM Wentworth, M Agostini, M Adams, TN Collingwood, ... Journal of Biological Chemistry 275 (8), 5754-5759, 2000 | 353 | 2000 |
| St John's wort, a herbal antidepressant, activates the steroid X receptor JM Wentworth, M Agostini, J Love, JW Schwabe, VKK Chatterjee Journal of Endocrinology 166 (3), R11, 2000 | 345 | 2000 |
| Zinc mining for protein domains JWR Schwabe, A Klug Nature structural biology 1 (6), 345-349, 1994 | 326 | 1994 |
| Mutations in the selenocysteine insertion sequence–binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans E Schoenmakers, M Agostini, C Mitchell, N Schoenmakers, L Papp, ... The Journal of clinical investigation 120 (12), 4220-4235, 2010 | 316 | 2010 |
| Co-operative and hierarchical binding of c-FLIP and caspase-8: a unified model defines how c-FLIP isoforms differentially control cell fate MA Hughes, IR Powley, R Jukes-Jones, S Horn, M Feoktistova, L Fairall, ... Molecular cell 61 (6), 834-849, 2016 | 276 | 2016 |
| International union of pharmacology. LXVI. Orphan nuclear receptors G Benoit, A Cooney, V Giguere, H Ingraham, M Lazar, G Muscat, ... Pharmacological reviews 58 (4), 798-836, 2006 | 271 | 2006 |
| Radical fringe positions the apical ectodermal ridge at the dorsoventral boundary of the vertebrate limb C Rodriguez-Esteban, JWR Schwabe, JDL Peña, B Foys, B Eshelman, ... Nature 386 (6623), 360-366, 1997 | 242 | 1997 |
