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Hayden Metsky
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Field-deployable viral diagnostics using CRISPR-Cas13
C Myhrvold, CA Freije, JS Gootenberg, OO Abudayyeh, HC Metsky, ...
Science 360 (6387), 444-448, 2018
11202018
Massively multiplexed nucleic acid detection with Cas13
CM Ackerman, C Myhrvold, SG Thakku, CA Freije, HC Metsky, DK Yang, ...
Nature 582 (7811), 277-282, 2020
5642020
Zika virus evolution and spread in the Americas
HC Metsky, CB Matranga, S Wohl, SF Schaffner, CA Freije, SM Winnicki, ...
Nature 546 (7658), 411-415, 2017
4232017
Genomic epidemiology reveals multiple introductions of Zika virus into the United States
ND Grubaugh, JT Ladner, MUG Kraemer, G Dudas, AL Tan, ...
Nature 546 (7658), 401-405, 2017
3622017
Programmable inhibition and detection of RNA viruses using Cas13
CA Freije, C Myhrvold, CK Boehm, AE Lin, NL Welch, A Carter, ...
Molecular cell 76 (5), 826-837. e11, 2019
3442019
CRISPR-based surveillance for COVID-19 using genomically-comprehensive machine learning design
HC Metsky, CA Freije, TSF Kosoko-Thoroddsen, PC Sabeti, C Myhrvold
BioRxiv, 2020.02. 26.967026, 2020
164*2020
Deployable CRISPR-Cas13a diagnostic tools to detect and report Ebola and Lassa virus cases in real-time
KG Barnes, AE Lachenauer, A Nitido, S Siddiqui, R Gross, B Beitzel, ...
Nature communications 11 (1), 4131, 2020
1272020
Capturing sequence diversity in metagenomes with comprehensive and scalable probe design
HC Metsky, KJ Siddle, A Gladden-Young, J Qu, DK Yang, P Brehio, ...
Nature Biotechnology 37 (2), 160, 2019
1112019
Rapid detection of Powassan virus in a patient with encephalitis by metagenomic sequencing
A Piantadosi, S Kanjilal, V Ganesh, A Khanna, EP Hyle, J Rosand, T Bold, ...
Clinical Infectious Diseases 66 (5), 789-792, 2018
562018
Designing sensitive viral diagnostics with machine learning
HC Metsky, NL Welch, PP Pillai, NJ Haradhvala, L Rumker, S Mantena, ...
Nature Biotechnology 40 (7), 1123-1131, 2022
48*2022
Combining genomics and epidemiology to track mumps virus transmission in the United States
S Wohl, HC Metsky, SF Schaffner, A Piantadosi, M Burns, JA Lewnard, ...
PLoS Biology 18 (2), e3000611, 2020
422020
Automatic Learning of Morphological Variations for Handling Out-of-Vocabulary Terms in Urdu-English MT
N Habash, H Metsky
Proceedings of the 8th Conference of the Association for Machine Translation …, 2008
122008
The Origins and Future of Sentinel: An Early-Warning System for Pandemic Preemption and Response
Y Botti-Lodovico, P Nair, D Nosamiefan, M Stremlau, S Schaffner, ...
Viruses 13 (8), 1605, 2021
82021
Broad Institute viral-ngs: v1. 13.3
C Tomkins-Tinch, S Ye, H Metsky, I Jungreis, R Sealfon, X Yang, ...
Zenodo. doi 10, 2016
72016
Capturing diverse microbial sequence with comprehensive and scalable probe design
HC Metsky, KJ Siddle, A Gladden-Young, J Qu, DK Yang, P Brehio, ...
bioRxiv, 279570, 2018
62018
Crispr system based droplet diagnostic systems and methods
CA Freije, C Myhrvold, H Metsky, P Sabeti, G Thakku, J Kehe, ...
US Patent App. 17/294,179, 2022
32022
Model-directed generation of CRISPR-Cas13a guide RNAs designs artificial sequences that improve nucleic acid detection
S Mantena, PP Pillai, BA Petros, NL Welch, C Myhrvold, PC Sabeti, ...
bioRxiv, 2023
22023
Sample analysis, presence determination of a target sequence
H Metsky, A Gnirke, C Matranga, D Park, P Sabeti
US Patent 11,332,783, 2022
2022
MULTIPLEXING HIGHLY EVOLVING VIRAL VARIANTS WITH SHERLOCK DETECTION METHOD
CA Freije, C Myhrvold, H Metsky, P Sabeti
US Patent App. 17/294,232, 2022
2022
DESIGNING SENSITIVE, SPECIFIC, AND OPTIMALLY ACTIVE BINDING MOLECULES FOR DIAGNOSTICS AND THERAPEUTICS
P Sabeti, H Metsky, C Myhrvold, N Haradhvala
US Patent App. 17/065,504, 2021
2021
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Articles 1–20