Current and future ophthalmic drug delivery systems: a shift to the posterior segment EM Del Amo, A Urtti Drug discovery today 13 (3-4), 135-143, 2008 | 568 | 2008 |
Pharmacokinetic aspects of retinal drug delivery EM Del Amo, AK Rimpelä, E Heikkinen, OK Kari, E Ramsay, T Lajunen, ... Progress in retinal and eye research 57, 134-185, 2017 | 550 | 2017 |
Pharmacokinetic role of L-type amino acid transporters LAT1 and LAT2 EM Del Amo, A Urtti, M Yliperttula European Journal of Pharmaceutical Sciences 35 (3), 161-174, 2008 | 380 | 2008 |
Rabbit as an animal model for intravitreal pharmacokinetics: Clinical predictability and quality of the published data EM Del Amo, A Urtti Experimental eye research 137, 111-124, 2015 | 209 | 2015 |
Design principles of ocular drug delivery systems: Importance of drug payload, release rate, and material properties A Subrizi, EM Del Amo, V Korzhikov-Vlakh, T Tennikova, M Ruponen, ... Drug discovery today 24 (8), 1446-1457, 2019 | 154 | 2019 |
Intravitreal clearance and volume of distribution of compounds in rabbits: In silico prediction and pharmacokinetic simulations for drug development EM Del Amo, KS Vellonen, H Kidron, A Urtti European Journal of Pharmaceutics and Biopharmaceutics 95, 215-226, 2015 | 135 | 2015 |
Corneal and conjunctival drug permeability: Systematic comparison and pharmacokinetic impact in the eye E Ramsay, EM Del Amo, E Toropainen, U Tengvall-Unadike, VP Ranta, ... European Journal of Pharmaceutical Sciences 119, 83-89, 2018 | 110 | 2018 |
Novel biodegradable polyesteramide microspheres for controlled drug delivery in Ophthalmology V Andrés-Guerrero, M Zong, E Ramsay, B Rojas, S Sarkhel, B Gallego, ... Journal of controlled release 211, 105-117, 2015 | 106 | 2015 |
Implications of melanin binding in ocular drug delivery AK Rimpelä, M Reinisalo, L Hellinen, E Grazhdankin, H Kidron, A Urtti, ... Advanced drug delivery reviews 126, 23-43, 2018 | 105 | 2018 |
In vitro–in vivo correlation in p-glycoprotein mediated transport in intestinal absorption EM Del Amo, AT Heikkinen, J Mönkkönen european journal of pharmaceutical sciences 36 (2-3), 200-211, 2009 | 76 | 2009 |
Prediction of the corneal permeability of drug-like compounds H Kidron, KS Vellonen, EM Del Amo, A Tissari, A Urtti Pharmaceutical research 27, 1398-1407, 2010 | 59 | 2010 |
Ocular barriers to retinal delivery of intravitreal liposomes: Impact of vitreoretinal interface S Tavakoli, K Peynshaert, T Lajunen, J Devoldere, EM Del Amo, ... Journal of controlled release 328, 952-961, 2020 | 55 | 2020 |
Prediction of ocular drug distribution from systemic blood circulation KS Vellonen, EM Soini, EM Del Amo, A Urtti Molecular pharmaceutics 13 (9), 2906-2911, 2016 | 53 | 2016 |
Olaparib significantly delays photoreceptor loss in a model for hereditary retinal degeneration A Sahaboglu, M Barth, E Secer, EM Amo, A Urtti, Y Arsenijevic, E Zrenner, ... Scientific Reports 6 (1), 39537, 2016 | 47 | 2016 |
Impact of chemical structure on conjunctival drug permeability: adopting porcine conjunctiva and cassette dosing for construction of in silico model E Ramsay, M Ruponen, T Picardat, U Tengvall, M Tuomainen, S Auriola, ... Journal of Pharmaceutical Sciences 106 (9), 2463-2471, 2017 | 45 | 2017 |
HDAC inhibition in the cpfl1 mouse protects degenerating cone photoreceptors in vivo D Trifunović, B Arango-Gonzalez, A Comitato, M Barth, EM Del Amo, ... Human molecular genetics 25 (20), 4462-4472, 2016 | 43 | 2016 |
Melanin binding study of clinical drugs with cassette dosing and rapid equilibrium dialysis inserts L Pelkonen, U Tengvall-Unadike, M Ruponen, H Kidron, EM Del Amo, ... European Journal of Pharmaceutical Sciences 109, 162-168, 2017 | 41 | 2017 |
Biopharmaceutics of topical ophthalmic suspensions: Importance of viscosity and particle size in ocular absorption of indomethacin E Toropainen, SJ Fraser-Miller, D Novakovic, EM Del Amo, KS Vellonen, ... Pharmaceutics 13 (4), 452, 2021 | 40 | 2021 |
Prediction of the vitreal half-life of small molecular drug-like compounds H Kidron, EM Del Amo, KS Vellonen, A Urtti Pharmaceutical research 29, 3302-3311, 2012 | 39 | 2012 |
Role of retinal pigment epithelium permeability in drug transfer between posterior eye segment and systemic blood circulation E Ramsay, M Hagström, KS Vellonen, S Boman, E Toropainen, ... European Journal of Pharmaceutics and Biopharmaceutics 143, 18-23, 2019 | 33 | 2019 |