Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins. R Perona, S Montaner, L Saniger, I Sanchez-Perez, R Bravo, JC Lacal Genes & development 11 (4), 463-475, 1997 | 794 | 1997 |
The Kaposi’s sarcoma-associated herpes virus G protein-coupled receptor up-regulates vascular endothelial growth factor expression and secretion through mitogen-activated … A Sodhi, S Montaner, V Patel, M Zohar, C Bais, EA Mesri, JS Gutkind Cancer research 60 (17), 4873-4880, 2000 | 575 | 2000 |
Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi's sarcomagenesis and can promote the tumorigenic potential of viral latent genes S Montaner, A Sodhi, A Molinolo, TH Bugge, ET Sawai, Y He, Y Li, ... Cancer cell 3 (1), 23-36, 2003 | 418 | 2003 |
Multiple signalling pathways lead to the activation of the nuclear factor κB by the Rho family of GTPases S Montaner, R Perona, L Saniger, JC Lacal Journal of Biological Chemistry 273 (21), 12779-12785, 1998 | 297 | 1998 |
The small GTP-binding protein Rho links G protein-coupled receptors and Gα12 to the serum response element and to cellular transformation C Fromm, OA Coso, S Montaner, N Xu, JS Gutkind Proceedings of the National Academy of Sciences 94 (19), 10098-10103, 1997 | 278 | 1997 |
The Kaposi’s sarcoma-associated herpesvirus G protein-coupled receptor promotes endothelial cell survival through the activation of Akt/protein kinase B S Montaner, A Sodhi, S Pece, EA Mesri, JS Gutkind Cancer research 61 (6), 2641-2648, 2001 | 263 | 2001 |
Viral hijacking of G-protein-coupled-receptor signalling networks A Sodhi, S Montaner, JS Gutkind Nature Reviews Molecular Cell Biology 5 (12), 998-1012, 2004 | 227 | 2004 |
MAPK and Akt act cooperatively but independently on hypoxia inducible factor-1α in rasV12 upregulation of VEGF A Sodhi, S Montaner, H Miyazaki, JS Gutkind Biochemical and biophysical research communications 287 (1), 292-300, 2001 | 215 | 2001 |
The TSC2/mTOR pathway drives endothelial cell transformation induced by the Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor A Sodhi, R Chaisuparat, J Hu, AK Ramsdell, BD Manning, EA Sausville, ... Cancer cell 10 (2), 133-143, 2006 | 212 | 2006 |
Akt plays a central role in sarcomagenesis induced by Kaposi's sarcoma herpesvirus-encoded G protein-coupled receptor A Sodhi, S Montaner, V Patel, JJ Gómez-Román, Y Li, EA Sausville, ... Proceedings of the National Academy of Sciences 101 (14), 4821-4826, 2004 | 171 | 2004 |
Hypoxic retinal Müller cells promote vascular permeability by HIF-1–dependent up-regulation of angiopoietin-like 4 X Xin, M Rodrigues, M Umapathi, F Kashiwabuchi, T Ma, ... Proceedings of the National Academy of Sciences 110 (36), E3425-E3434, 2013 | 156 | 2013 |
VEGF secreted by hypoxic Müller cells induces MMP-2 expression and activity in endothelial cells to promote retinal neovascularization in proliferative diabetic retinopathy M Rodrigues, X Xin, K Jee, S Babapoor-Farrokhran, F Kashiwabuchi, ... Diabetes 62 (11), 3863-3873, 2013 | 152 | 2013 |
Angiopoietin-like 4 is a potent angiogenic factor and a novel therapeutic target for patients with proliferative diabetic retinopathy S Babapoor-Farrokhran, K Jee, B Puchner, SJ Hassan, X Xin, ... Proceedings of the National Academy of Sciences 112 (23), E3030-E3039, 2015 | 127 | 2015 |
The small GTPase Rac1 links the Kaposi sarcoma–associated herpesvirus vGPCR to cytokine secretion and paracrine neoplasia S Montaner, A Sodhi, JM Servitja, AK Ramsdell, A Barac, ET Sawai, ... Blood 104 (9), 2903-2911, 2004 | 125 | 2004 |
Generation of phosphorylcholine as an essential event in the activation of Raf‐1 and MAP‐kinases in growth factors‐induced mitogenic stimulation B Jiménez, L del Peso, S Montaner, P Esteve, JC Lacal Journal of cellular biochemistry 57 (1), 141-149, 1995 | 125 | 1995 |
Viral G protein-coupled receptor up-regulates Angiopoietin-like 4 promoting angiogenesis and vascular permeability in Kaposi's sarcoma T Ma, BC Jham, J Hu, ER Friedman, JR Basile, A Molinolo, A Sodhi, ... Proceedings of the National Academy of Sciences 107 (32), 14363-14368, 2010 | 122 | 2010 |
Hypoxia-inducible factor 1 upregulation of both VEGF and ANGPTL4 is required to promote the angiogenic phenotype in uveal melanoma K Hu, S Babapoor-Farrokhran, M Rodrigues, M Deshpande, B Puchner, ... Oncotarget 7 (7), 7816, 2016 | 120 | 2016 |
Activation of serum response factor by RhoA is mediated by the nuclear factor-κB and C/EBP transcription factors S Montaner, R Perona, L Saniger, JC Lacal Journal of Biological Chemistry 274 (13), 8506-8515, 1999 | 120 | 1999 |
The Kaposi's Sarcoma–Associated Herpesvirus G Protein–Coupled Receptor as a Therapeutic Target for the Treatment of Kaposi's Sarcoma S Montaner, A Sodhi, AK Ramsdell, D Martin, J Hu, ET Sawai, JS Gutkind Cancer research 66 (1), 168-174, 2006 | 114 | 2006 |
Lysophosphatidic acid activates nuclear factor kappa B and induces proinflammatory gene expression in endothelial cells A Palmetshofer, SC Robson, V Nehls Thrombosis and haemostasis 82 (11), 1532-1537, 1999 | 110 | 1999 |