| Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ... Cell Death & Differentiation 25 (3), 486-541, 2018 | 5308 | 2018 |
| Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation YS Cho, S Challa, D Moquin, R Genga, TD Ray, M Guildford, FKM Chan Cell 137 (6), 1112-1123, 2009 | 2533 | 2009 |
| A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling FKM Chan, HJ Chun, L Zheng, RM Siegel, KL Bui, MJ Lenardo Science 288 (5475), 2351-2354, 2000 | 1242 | 2000 |
| Mature T lymphocyte apoptosis—immune regulation in a dynamic and unpredictable antigenic environment M Lenardo, FKM Chan, F Hornung, H McFarland, R Siegel, J Wang, ... Annual review of immunology 17 (1), 221-253, 1999 | 1235 | 1999 |
| The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis J Li, T McQuade, AB Siemer, J Napetschnig, K Moriwaki, YS Hsiao, ... Cell 150 (2), 339-350, 2012 | 1202 | 2012 |
| Essential versus accessory aspects of cell death: recommendations of the NCCD 2015 L Galluzzi, BS Pedro, I Vitale, SA Aaronson, JM Abrams, D Adam, ... Cell Death & Differentiation 22 (1), 58-73, 2015 | 1143 | 2015 |
| Detection of necrosis by release of lactate dehydrogenase activity FKM Chan, K Moriwaki, MJ De Rosa Immune Homeostasis: Methods and Protocols, 65-70, 2013 | 911 | 2013 |
| Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations RM Siegel, JK Frederiksen, DA Zacharias, FKM Chan, M Johnson, ... Science 288 (5475), 2354-2357, 2000 | 888 | 2000 |
| Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II J Wang, L Zheng, A Lobito, FKM Chan, J Dale, M Sneller, X Yao, JM Puck, ... Cell 98 (1), 47-58, 1999 | 767 | 1999 |
| A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses FKM Chan, J Shisler, JG Bixby, M Felices, L Zheng, M Appel, J Orenstein, ... Journal of Biological Chemistry 278 (51), 51613-51621, 2003 | 597 | 2003 |
| RIP3 induces apoptosis independent of pronecrotic kinase activity P Mandal, SB Berger, S Pillay, K Moriwaki, C Huang, H Guo, JD Lich, ... Molecular cell 56 (4), 481-495, 2014 | 565 | 2014 |
| CTLA-4-Mediated inhibition of early events of T cell proliferation MC Brunner, CA Chambers, FKM Chan, J Hanke, A Winoto, JP Allison The Journal of Immunology 162 (10), 5813-5820, 1999 | 560 | 1999 |
| The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity RM Siegel, F Ka-Ming Chan, HJ Chun, MJ Lenardo Nature immunology 1 (6), 469-474, 2000 | 557 | 2000 |
| Necroptosis: mechanisms and relevance to disease L Galluzzi, O Kepp, FKM Chan, G Kroemer Annual Review of Pathology: Mechanisms of Disease 12, 103-130, 2017 | 546 | 2017 |
| Identification of Human and Mouse p19, a Novel CDK4 and CDK6 Inhibitor with Homology to p16ink4 FKM Chan, J Zhang, L Cheng, DN Shapiro, A Winoto Molecular and cellular biology 15 (5), 2682-2688, 1995 | 537 | 1995 |
| Functional complementation between FADD and RIP1 in embryos and lymphocytes H Zhang, X Zhou, T McQuade, J Li, FKM Chan, J Zhang Nature 471 (7338), 373-376, 2011 | 463 | 2011 |
| RIP3: a molecular switch for necrosis and inflammation K Moriwaki, FKM Chan Genes & development 27 (15), 1640-1649, 2013 | 412 | 2013 |
| A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection BJ Cainan, S Szychowski, FKM Chan, D Cado, A Winoto Immunity 3 (3), 273-282, 1995 | 401 | 1995 |
| Functional redundancy of the Nur77 and Nor‐1 orphan steroid receptors in T‐cell apoptosis LEC Cheng, FKM Chan, D Cado, A Winoto The EMBO journal, 1997 | 395 | 1997 |
| Programmed necrosis in the cross talk of cell death and inflammation FKM Chan, NF Luz, K Moriwaki Annual review of immunology 33, 79-106, 2015 | 359 | 2015 |
Richard SiegelNovartis Institutes of BioMedical ResearchVerified email at novartis.com
