| The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity J Barretina, G Caponigro, N Stransky, K Venkatesan, AA Margolin, S Kim, ... Nature 483 (7391), 603-607, 2012 | 7723 | 2012 |
| Activation of a metabolic gene regulatory network downstream of mTOR complex 1 K Düvel, JL Yecies, S Menon, P Raman, AI Lipovsky, AL Souza, ... Molecular cell 39 (2), 171-183, 2010 | 2190 | 2010 |
| The landscape of genomic alterations across childhood cancers SN Gröbner, BC Worst, J Weischenfeldt, I Buchhalter, K Kleinheinz, ... Nature 555 (7696), 321-327, 2018 | 1271 | 2018 |
| Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy E Sotillo, DM Barrett, KL Black, A Bagashev, D Oldridge, G Wu, ... Cancer discovery 5 (12), 1282-1295, 2015 | 1190 | 2015 |
| Integrated molecular meta-analysis of 1,000 pediatric high-grade and diffuse intrinsic pontine glioma A Mackay, A Burford, D Carvalho, E Izquierdo, J Fazal-Salom, KR Taylor, ... Cancer cell 32 (4), 520-537. e5, 2017 | 845 | 2017 |
| Comprehensive analysis of hypermutation in human cancer BB Campbell, N Light, D Fabrizio, M Zatzman, F Fuligni, R de Borja, ... Cell 171 (5), 1042-1056. e10, 2017 | 689 | 2017 |
| Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signaling A Britschgi, A Bill, H Brinkhaus, C Rothwell, I Clay, S Duss, M Rebhan, ... Proceedings of the National Academy of Sciences 110 (11), E1026-E1034, 2013 | 326 | 2013 |
| The membrane protein data bank P Raman, V Cherezov, M Caffrey Cellular and Molecular Life Sciences 63, 36-51, 2006 | 223 | 2006 |
| Integrated proteogenomic characterization across major histological types of pediatric brain cancer F Petralia, N Tignor, B Reva, M Koptyra, S Chowdhury, D Rykunov, A Krek, ... Cell 183 (7), 1962-1985. e31, 2020 | 204 | 2020 |
| Molecular, pathological, radiological, and immune profiling of non-brainstem pediatric high-grade glioma from the HERBY phase II randomized trial A Mackay, A Burford, V Molinari, DTW Jones, E Izquierdo, ... Cancer cell 33 (5), 829-842. e5, 2018 | 177 | 2018 |
| Transcriptome analysis of IL-10-stimulated (M2c) macrophages by next-generation sequencing EB Lurier, D Dalton, W Dampier, P Raman, S Nassiri, NM Ferraro, ... Immunobiology 222 (7), 847-856, 2017 | 175 | 2017 |
| Selective inhibition of TGFβ1 activation overcomes primary resistance to checkpoint blockade therapy by altering tumor immune landscape CJ Martin, A Datta, C Littlefield, A Kalra, C Chapron, S Wawersik, ... Science translational medicine 12 (536), eaay8456, 2020 | 171 | 2020 |
| Identification of GPC2 as an oncoprotein and candidate immunotherapeutic target in high-risk neuroblastoma KR Bosse, P Raman, Z Zhu, M Lane, D Martinez, S Heitzeneder, KS Rathi, ... Cancer cell 32 (3), 295-309. e12, 2017 | 167 | 2017 |
| CASC15-S is a tumor suppressor lncRNA at the 6p22 neuroblastoma susceptibility locus MR Russell, A Penikis, DA Oldridge, JR Alvarez-Dominguez, L McDaniel, ... Cancer research 75 (15), 3155-3166, 2015 | 156 | 2015 |
| Genomic profiling of childhood tumor patient-derived xenograft models to enable rational clinical trial design JL Rokita, KS Rathi, MF Cardenas, KA Upton, J Jayaseelan, KL Cross, ... Cell reports 29 (6), 1675-1689. e9, 2019 | 150 | 2019 |
| Enrichment of targetable mutations in the relapsed neuroblastoma genome OM Padovan-Merhar, P Raman, I Ostrovnaya, K Kalletla, KR Rubnitz, ... PLoS genetics 12 (12), e1006501, 2016 | 128 | 2016 |
| Crizotinib synergizes with chemotherapy in preclinical models of neuroblastoma K Krytska, HT Ryles, R Sano, P Raman, NR Infarinato, TD Hansel, ... Clinical Cancer Research 22 (4), 948-960, 2016 | 115 | 2016 |
| A LIN28B-RAN-AURKA signaling network promotes neuroblastoma tumorigenesis RW Schnepp, P Khurana, EF Attiyeh, P Raman, SE Chodosh, ... Cancer cell 28 (5), 599-609, 2015 | 103 | 2015 |
| Englerin A agonizes the TRPC4/C5 cation channels to inhibit tumor cell line proliferation C Carson, P Raman, J Tullai, L Xu, M Henault, E Thomas, S Yeola, J Lao, ... PloS one 10 (6), e0127498, 2015 | 101 | 2015 |
| Clinical utility of custom-designed NGS panel testing in pediatric tumors LF Surrey, SP MacFarland, F Chang, K Cao, KS Rathi, GT Akgumus, ... Genome medicine 11, 1-14, 2019 | 95 | 2019 |
John M MarisProfessor Pediatrics, Children's Hospital of Philadelphia and University of PennsylvaniaVerified email at chop.edu
