| Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating … P Godoy, NJ Hewitt, U Albrecht, ME Andersen, N Ansari, S Bhattacharya, ... Archives of toxicology 87, 1315-1530, 2013 | 1439 | 2013 |
| A single-cell-based model of tumor growth in vitro: monolayers and spheroids D Drasdo, S Hoehme Physical biology 2 (3), 133, 2005 | 510 | 2005 |
| Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regeneration S Hoehme, M Brulport, A Bauer, E Bedawy, W Schormann, M Hermes, ... Proceedings of the National Academy of Sciences 107 (23), 10371-10376, 2010 | 411 | 2010 |
| Adverse outcome pathways: opportunities, limitations and open questions M Leist, A Ghallab, R Graepel, R Marchan, R Hassan, SH Bennekou, ... Archives of toxicology 91, 3477-3505, 2017 | 351 | 2017 |
| On the role of physics in the growth and pattern formation of multi-cellular systems: What can we learn from individual-cell based models? D Drasdo, S Hoehme, M Block Journal of Statistical Physics 128 (1-2), 287-345, 2007 | 211 | 2007 |
| A cell-based simulation software for multi-cellular systems S Hoehme, D Drasdo Bioinformatics 26 (20), 2641-2642, 2010 | 196 | 2010 |
| Individual-based approaches to birth and death in avascu1ar tumors D Drasdo, S Höhme Mathematical and Computer Modelling 37 (11), 1163-1175, 2003 | 168 | 2003 |
| Protocols for staining of bile canalicular and sinusoidal networks of human, mouse and pig livers, three-dimensional reconstruction and quantification of tissue … S Hammad, S Hoehme, A Friebel, I Von Recklinghausen, A Othman, ... Archives of toxicology 88, 1161-1183, 2014 | 150 | 2014 |
| Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseases A Ghallab, G Celliere, SG Henkel, D Driesch, S Hoehme, U Hofmann, ... Journal of hepatology 64 (4), 860-871, 2016 | 127 | 2016 |
| Integrated metabolic spatial‐temporal model for the prediction of ammonia detoxification during liver damage and regeneration F Schliess, S Hoehme, SG Henkel, A Ghallab, D Driesch, J Böttger, ... Hepatology 60 (6), 2040-2051, 2014 | 118 | 2014 |
| Mathematical modelling of liver regeneration after intoxication with CCl 4 S Höhme, JG Hengstler, M Brulport, M Schäfer, A Bauer, R Gebhardt, ... Chemico-biological interactions 168 (1), 74-93, 2007 | 101 | 2007 |
| How predictive quantitative modelling of tissue organisation can inform liver disease pathogenesis D Drasdo, S Hoehme, JG Hengstler Journal of hepatology 61 (4), 951-956, 2014 | 84 | 2014 |
| Modeling the impact of granular embedding media, and pulling versus pushing cells on growing cell clones D Drasdo, S Hoehme New Journal of Physics 14 (5), 055025, 2012 | 67 | 2012 |
| A quantitative high-resolution computational mechanics cell model for growing and regenerating tissues P Van Liedekerke, J Neitsch, T Johann, E Warmt, I Gonzàlez-Valverde, ... Biomechanics and modeling in mechanobiology 19, 189-220, 2020 | 57 | 2020 |
| Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity A Ghallab, R Hassan, U Hofmann, A Friebel, Z Hobloss, L Brackhagen, ... Journal of Hepatology 77 (1), 71-83, 2022 | 50 | 2022 |
| TiQuant: software for tissue analysis, quantification and surface reconstruction A Friebel, J Neitsch, T Johann, S Hammad, JG Hengstler, D Drasdo, ... Bioinformatics 31 (19), 3234-3236, 2015 | 49 | 2015 |
| The virtual liver: state of the art and future perspectives D Drasdo, J Bode, U Dahmen, O Dirsch, S Dooley, R Gebhardt, A Ghallab, ... Archives of toxicology 88, 2071-2075, 2014 | 43 | 2014 |
| Phenotype and growth behavior of residual β-catenin-positive hepatocytes in livers of β-catenin-deficient mice A Braeuning, Y Singh, B Rignall, A Buchmann, S Hammad, A Othman, ... Histochemistry and cell biology 134, 469-481, 2010 | 43 | 2010 |
| Spatio-Temporal Multiscale Analysis of Western Diet-Fed Mice Reveals a Translationally Relevant Sequence of Events during NAFLD Progression A Ghallab, M Myllys, A Friebel, J Duda, K Edlund, E Halilbasic, M Vucur, ... Cells 10 (10), 2516, 2021 | 39 | 2021 |
| Intravital dynamic and correlative imaging reveals diffusion‐dominated canalicular and flow‐augmented ductular bile flux N Vartak, G Guenther, F Joly, A Damle‐Vartak, G Wibbelt, J Fickel, S Jörs, ... Hepatology, 2020 | 39* | 2020 |
Dirk DrasdoINRIA OR Max-Planck OR IZBI OR IFADO OR IMISE OR Warwick OR University of Goettingen OR RWTH AachenBestätigte E-Mail-Adresse bei inria.fr
