| Neurodegenerative diseases and oxidative stress KJ Barnham, CL Masters, AI Bush Nature reviews Drug discovery 3 (3), 205-214, 2004 | 3585 | 2004 |
| Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease BR Stockwell, JPF Angeli, H Bayir, AI Bush, M Conrad, SJ Dixon, S Fulda, ... Cell 171 (2), 273-285, 2017 | 3406 | 2017 |
| Soluble pool of Aβ amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease CA McLean, RA Cherny, FW Fraser, SJ Fuller, MJ Smith, K Vbeyreuther, ... Annals of neurology 46 (6), 860-866, 1999 | 2393 | 1999 |
| The neurobiology of zinc in health and disease CJ Frederickson, JY Koh, AI Bush Nature Reviews Neuroscience 6 (6), 449-462, 2005 | 1898 | 2005 |
| Rapid induction of Alzheimer Aβ amyloid formation by zinc AI Bush, WH Pettingell, G Multhaup, M d Paradis, JP Vonsattel, JF Gusella, ... Science 265 (5177), 1464-1467, 1994 | 1889 | 1994 |
| Treatment with a copper-zinc chelator markedly and rapidly inhibits β-amyloid accumulation in Alzheimer's disease transgenic mice RA Cherny, CS Atwood, ME Xilinas, DN Gray, WD Jones, CA McLean, ... Neuron 30 (3), 665-676, 2001 | 1775 | 2001 |
| The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease gene RE Tanzi, K Petrukhin, I Chernov, JL Pellequer, W Wasco, B Ross, ... Nature genetics 5 (4), 344-350, 1993 | 1616 | 1993 |
| The metallobiology of Alzheimer's disease AI Bush Trends in neurosciences 26 (4), 207-214, 2003 | 1485 | 2003 |
| The Aβ peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction X Huang, CS Atwood, MA Hartshorn, G Multhaup, LE Goldstein, ... Biochemistry 38 (24), 7609-7616, 1999 | 1367 | 1999 |
| Dramatic aggregation of Alzheimer Aβ by Cu (II) is induced by conditions representing physiological acidosis CS Atwood, RD Moir, X Huang, RC Scarpa, NME Bacarra, DM Romano, ... Journal of Biological Chemistry 273 (21), 12817-12826, 1998 | 1273 | 1998 |
| Oxidative stress in psychiatric disorders: evidence base and therapeutic implications F Ng, M Berk, O Dean, AI Bush The the International Journal of Neuropsychopharmacology 11 (6), 851-876, 2008 | 1210 | 2008 |
| Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Aβ amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial CW Ritchie, AI Bush, A Mackinnon, S Macfarlane, M Mastwyk, ... Archives of neurology 60 (12), 1685-1691, 2003 | 1166 | 2003 |
| Cu (II) potentiation of Alzheimer Aβ neurotoxicity: correlation with cell-free hydrogen peroxide production and metal reduction X Huang, MP Cuajungco, CS Atwood, MA Hartshorn, JDA Tyndall, ... Journal of Biological Chemistry 274 (52), 37111-37116, 1999 | 974 | 1999 |
| Metals and neuroscience AI Bush Current opinion in chemical biology 4 (2), 184-191, 2000 | 917 | 2000 |
| Alzheimer's disease amyloid-β binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits CC Curtain, F Ali, I Volitakis, RA Cherny, RS Norton, K Beyreuther, ... Journal of Biological Chemistry 276 (23), 20466-20473, 2001 | 802 | 2001 |
| Characterization of Copper Interactions with Alzheimer Amyloid β Peptides: Identification of an Attomolar‐Affinity Copper Binding Site on Amyloid β1‐42 CS Atwood, RC Scarpa, X Huang, RD Moir, WD Jones, DP Fairlie, ... Journal of neurochemistry 75 (3), 1219-1233, 2000 | 797 | 2000 |
| Safety, efficacy, and biomarker findings of PBT2 in targeting Aβ as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial L Lannfelt, K Blennow, H Zetterberg, S Batsman, D Ames, J Harrison, ... The Lancet Neurology 7 (9), 779-786, 2008 | 790 | 2008 |
| Metals in Alzheimer's and Parkinson's diseases KJ Barnham, AI Bush Current opinion in chemical biology 12 (2), 222-228, 2008 | 755 | 2008 |
| Metalloenzyme-like activity of Alzheimer's disease β-amyloid: Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H2O2 C Opazo, X Huang, RA Cherny, RD Moir, AE Roher, AR White, R Cappai, ... Journal of Biological Chemistry 277 (43), 40302-40308, 2002 | 754 | 2002 |
| Zinc in the physiology and pathology of the CNS SL Sensi, P Paoletti, AI Bush, I Sekler Nature reviews neuroscience 10 (11), 780-791, 2009 | 753 | 2009 |
Colin Louis MastersThe University of MelbourneVerified email at florey.edu.au
