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Nicolas Malaquin
Nicolas Malaquin
CENTRE DE RECHERCHE DU CHUM
Verified email at ssss.gouv.qc.ca
Title
Cited by
Cited by
Year
Keeping the senescence secretome under control: molecular reins on the senescence-associated secretory phenotype
N Malaquin, A Martinez, F Rodier
Experimental gerontology 82, 39-49, 2016
2392016
Exploiting interconnected synthetic lethal interactions between PARP inhibition and cancer cell reversible senescence
H Fleury, N Malaquin, V Tu, S Gilbert, A Martinez, MA Olivier, A Sauriol, ...
Nature communications 10 (1), 2556, 2019
1702019
Defective DNA single-strand break repair is responsible for senescence and neoplastic escape of epithelial cells
J Nassour, S Martien, N Martin, E Deruy, E Tomellini, N Malaquin, ...
Nature communications 7 (1), 10399, 2016
1242016
DDR-mediated crosstalk between DNA-damaged cells and their microenvironment
N Malaquin, A Carrier-Leclerc, M Dessureault, F Rodier
Frontiers in genetics 6, 132029, 2015
1162015
Senescent fibroblasts enhance early skin carcinogenic events via a paracrine MMP-PAR-1 axis
N Malaquin, C Vercamer, F Bouali, S Martien, E Deruy, N Wernert, ...
PloS one 8 (5), e63607, 2013
1082013
Senescence-associated oxidative DNA damage promotes the generation of neoplastic cells
K Gosselin, S Martien, A Pourtier, C Vercamer, P Ostoich, L Morat, ...
Cancer research 69 (20), 7917-7925, 2009
1082009
ATF6α regulates morphological changes associated with senescence in human fibroblasts
C Druelle, C Drullion, J Desle, N Martin, L Saas, J Cormenier, N Malaquin, ...
Oncotarget 7 (42), 67699, 2016
782016
Cellular senescence involves an intracrine prostaglandin E2 pathway in human fibroblasts
S Martien, O Pluquet, C Vercamer, N Malaquin, N Martin, K Gosselin, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2013
452013
DNA damage-but not enzalutamide-induced senescence in prostate cancer promotes senolytic Bcl-xL inhibitor sensitivity
N Malaquin, A Vancayseele, S Gilbert, L Antenor-Habazac, MA Olivier, ...
Cells 9 (7), 1593, 2020
422020
Loss of Hypermethylated in Cancer 1 (HIC1) in breast cancer cells contributes to stress-induced migration and invasion through β-2 adrenergic receptor (ADRB2) misregulation
G Boulay, N Malaquin, I Loison, B Foveau, C Van Rechem, BR Rood, ...
Journal of Biological Chemistry 287 (8), 5379-5389, 2012
422012
Level of macroautophagy drives senescent keratinocytes into cell death or neoplastic evasion
E Deruy, J Nassour, N Martin, C Vercamer, N Malaquin, J Bertout, F Chelli, ...
Cell Death & Disease 5 (12), e1577-e1577, 2014
372014
Senolytic targeting of Bcl-2 anti-apoptotic family increases cell death in irradiated sarcoma cells
J Lafontaine, GB Cardin, N Malaquin, JS Boisvert, F Rodier, P Wong
Cancers 13 (3), 386, 2021
332021
Assessing functional roles of the senescence-associated secretory phenotype (SASP)
N Malaquin, V Tu, F Rodier
Cellular Senescence: Methods and Protocols, 45-55, 2019
302019
Non‐canonical ATM/MRN activities temporally define the senescence secretory program
N Malaquin, MA Olivier, A Martinez, S Nadeau, C Sawchyn, JP Coppé, ...
EMBO reports 21 (10), e50718, 2020
252020
Biomarkers of cardiometabolic complications in survivors of childhood acute lymphoblastic leukemia
S Morel, P Léveillé, M Samoilenko, A Franco, J England, N Malaquin, ...
Scientific reports 10 (1), 21507, 2020
232020
mTOR as a senescence manipulation target: A forked road
S Saoudaoui, M Bernard, GB Cardin, N Malaquin, A Christopoulos, ...
Advances in Cancer Research 150, 335-363, 2021
152021
Homologous recombination-mediated irreversible genome damage underlies telomere-induced senescence
S Ghadaouia, MA Olivier, A Martinez, T Kientega, J Qin, ...
Nucleic Acids Research 49 (20), 11690-11707, 2021
122021
Telomeric dysfunction triggers an unstable growth arrest leading to irreparable genomic lesions and entry into cellular senescence
S Ghadaouia, MA Olivier, A Martinez, N Malaquin, GB Cardin, F Rodier
bioRxiv, 442533, 2018
42018
Targeting IKKε in Androgen-Independent Prostate Cancer Causes Phenotypic Senescence and Genomic Instability
S Gilbert, B Péant, N Malaquin, V Tu, H Fleury, K Leclerc-Desaulniers, ...
Molecular Cancer Therapeutics 21 (3), 407-418, 2022
22022
53BP1 mediates sensitivity to chemotherapy and is associated with poor clinical outcomes in high-grade serous ovarian cancer
M Skulimowski, J Bourbonnais, N Malaquin, H Fleury, I Clement, ...
bioRxiv, 2023.09. 30.560286, 2023
2023
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