N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation PS Knoepfler, PF Cheng, RN Eisenman Genes & development 16 (20), 2699-2712, 2002 | 611 | 2002 |
Deconstructing stem cell tumorigenicity: a roadmap to safe regenerative medicine PS Knoepfler Stem cells 27 (5), 1050-1056, 2009 | 552 | 2009 |
Sin meets NuRD and other tails of repression PS Knoepfler, RN Eisenman Cell 99 (5), 447-450, 1999 | 485 | 1999 |
Myc influences global chromatin structure PS Knoepfler, X Zhang, PF Cheng, PR Gafken, SB McMahon, ... The EMBO journal 25 (12), 2723-2734, 2006 | 438 | 2006 |
Pbx marks genes for activation by MyoD indicating a role for a homeodomain protein in establishing myogenic potential CA Berkes, DA Bergstrom, BH Penn, KJ Seaver, PS Knoepfler, ... Molecular cell 14 (4), 465-477, 2004 | 368 | 2004 |
Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity E Laurenti, B Varnum-Finney, A Wilson, I Ferrero, WE Blanco-Bose, ... Cell stem cell 3 (6), 611-624, 2008 | 322 | 2008 |
Selling stem cells in the USA: assessing the direct-to-consumer industry L Turner, P Knoepfler Cell stem cell 19 (2), 154-157, 2016 | 313 | 2016 |
Nmyc plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation T Okubo, PS Knoepfler, RN Eisenman, BLM Hogan Oxford University Press for The Company of Biologists Limited 132 (6), 1363-1374, 2005 | 256 | 2005 |
Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1 PS Knoepfler, KR Calvo, H Chen, SE Antonarakis, MP Kamps Proceedings of the National Academy of Sciences 94 (26), 14553-14558, 1997 | 240 | 1997 |
The pentapeptide motif of Hox proteins is required for cooperative DNA binding with Pbx1, physically contacts Pbx1, and enhances DNA binding by Pbx1 PS Knoepfler, MP Kamps Molecular and Cellular Biology 15 (10), 5811-5819, 1995 | 201 | 1995 |
N-myc Is an Essential Downstream Effector of Shh Signaling during both Normal and Neoplastic Cerebellar Growth BA Hatton, PS Knoepfler, AM Kenney, DH Rowitch, IM de Alborán, ... Cancer research 66 (17), 8655-8661, 2006 | 195 | 2006 |
Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes Q Lu, PS Knoepfler, J Scheele, DD Wright, MP Kamps Molecular and Cellular Biology 15 (7), 3786-3795, 1995 | 184 | 1995 |
N-Myc regulates a widespread euchromatic program in the human genome partially independent of its role as a classical transcription factor R Cotterman, VX Jin, SR Krig, JM Lemen, A Wey, PJ Farnham, ... Cancer research 68 (23), 9654-9662, 2008 | 172 | 2008 |
Myc goes global: new tricks for an old oncogene PS Knoepfler Cancer research 67 (11), 5061-5063, 2007 | 169 | 2007 |
Division and apoptosis of E2f-deficient retinal progenitors D Chen, M Pacal, P Wenzel, PS Knoepfler, G Leone, R Bremner Nature 462 (7275), 925-929, 2009 | 166 | 2009 |
The Smad transcriptional corepressor TGIF recruits mSin3 D Wotton, PS Knoepfler, CD Laherty, RN Eisenman, J Massague | 160 | 2001 |
Why myc? An unexpected ingredient in the stem cell cocktail PS Knoepfler Cell stem cell 2 (1), 18-21, 2008 | 149 | 2008 |
Histone H3. 3 mutations: a variant path to cancer BTK Yuen, PS Knoepfler Cancer cell 24 (5), 567-574, 2013 | 145 | 2013 |
Myc maintains embryonic stem cell pluripotency and self-renewal NV Varlakhanova, RF Cotterman, WN deVries, J Morgan, LR Donahue, ... Differentiation 80 (1), 9-19, 2010 | 145 | 2010 |
A conserved motif N-terminal to the DNA-binding domains of myogenic bHLH transcription factors mediates cooperative DNA binding with pbx-Meis1/Prep1 PS Knoepfler, DA Bergstrom, T Uetsuki, L Dac-Korytko, YH Sun, ... Nucleic acids research 27 (18), 3752-3767, 1999 | 132 | 1999 |