Fructose-1, 6-bisphosphate and aldolase mediate glucose sensing by AMPK CS Zhang, SA Hawley, Y Zong, M Li, Z Wang, A Gray, T Ma, J Cui, ... Nature 548 (7665), 112-116, 2017 | 556 | 2017 |
The lysosomal v-ATPase-Ragulator complex is a common activator for AMPK and mTORC1, acting as a switch between catabolism and anabolism CS Zhang, B Jiang, M Li, M Zhu, Y Peng, YL Zhang, YQ Wu, TY Li, ... Cell metabolism 20 (3), 526-540, 2014 | 514 | 2014 |
GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy SY Lin, TY Li, Q Liu, C Zhang, X Li, Y Chen, SM Zhang, G Lian, Q Liu, ... Science 336 (6080), 477-481, 2012 | 387 | 2012 |
AMP as a low-energy charge signal autonomously initiates assembly of AXIN-AMPK-LKB1 complex for AMPK activation YL Zhang, H Guo, CS Zhang, SY Lin, Z Yin, Y Peng, H Luo, Y Shi, G Lian, ... Cell metabolism 18 (4), 546-555, 2013 | 263 | 2013 |
Low-dose metformin targets the lysosomal AMPK pathway through PEN2 T Ma, X Tian, B Zhang, M Li, Y Wang, C Yang, J Wu, X Wei, Q Qu, Y Yu, ... Nature 603 (7899), 159-165, 2022 | 257 | 2022 |
Metformin activates AMPK through the lysosomal pathway CS Zhang, M Li, T Ma, Y Zong, J Cui, JW Feng, YQ Wu, SY Lin, SC Lin Cell metabolism 24 (4), 521-522, 2016 | 239 | 2016 |
Axin is a scaffold protein in TGF‐β signaling that promotes degradation of Smad7 by Arkadia W Liu, H Rui, J Wang, S Lin, Y He, M Chen, Q Li, Z Ye, S Zhang, SC Chan, ... The EMBO journal 25 (8), 1646-1658, 2006 | 207 | 2006 |
Axin stimulates p53 functions by activation of HIPK2 kinase through multimeric complex formation Y Rui, Z Xu, S Lin, Q Li, H Rui, W Luo, HM Zhou, PY Cheung, Z Wu, Z Ye, ... The EMBO journal 23 (23), 4583-4594, 2004 | 207 | 2004 |
Hierarchical activation of compartmentalized pools of AMPK depends on severity of nutrient or energy stress Y Zong, CS Zhang, M Li, W Wang, Z Wang, SA Hawley, T Ma, JW Feng, ... Cell Research 29 (6), 460-473, 2019 | 119 | 2019 |
ULK1/2 constitute a bifurcate node controlling glucose metabolic fluxes in addition to autophagy TY Li, Y Sun, Y Liang, Q Liu, Y Shi, CS Zhang, C Zhang, L Song, P Zhang, ... Molecular cell 62 (3), 359-370, 2016 | 114 | 2016 |
Transient receptor potential V channels are essential for glucose sensing by aldolase and AMPK M Li, CS Zhang, Y Zong, JW Feng, T Ma, M Hu, Z Lin, X Li, C Xie, Y Wu, ... Cell metabolism 30 (3), 508-524. e12, 2019 | 97 | 2019 |
Axin determines cell fate by controlling the p53 activation threshold after DNA damage Q Li, S Lin, X Wang, G Lian, Z Lu, H Guo, K Ruan, Y Wang, Z Ye, J Han, ... Nature cell biology 11 (9), 1128-1134, 2009 | 96 | 2009 |
Periostin contributes to the acquisition of multipotent stem cell-like properties in human mammary epithelial cells and breast cancer cells X Wang, J Liu, Z Wang, Y Huang, W Liu, X Zhu, Y Cai, X Fang, S Lin, ... PloS one 8 (8), e72962, 2013 | 84 | 2013 |
The Axin/TNKS complex interacts with KIF3A and is required for insulin-stimulated GLUT4 translocation HL Guo, C Zhang, Q Liu, Q Li, G Lian, D Wu, X Li, W Zhang, Y Shen, Z Ye, ... Cell research 22 (8), 1246-1257, 2012 | 81 | 2012 |
Twist2 promotes self-renewal of liver cancer stem-like cells by regulating CD24 AY Liu, Y Cai, Y Mao, Y Lin, H Zheng, T Wu, Y Huang, X Fang, S Lin, ... Carcinogenesis 35 (3), 537-545, 2014 | 76 | 2014 |
Tob1 controls dorsal development of zebrafish embryos by antagonizing maternal β-catenin transcriptional activity B Xiong, Y Rui, M Zhang, K Shi, S Jia, T Tian, K Yin, H Huang, S Lin, ... Developmental cell 11 (2), 225-238, 2006 | 75 | 2006 |
Axin contains three separable domains that confer intramolecular, homodimeric, and heterodimeric interactions involved in distinct functions W Luo, H Zou, L Jin, S Lin, Q Li, Z Ye, H Rui, SC Lin Journal of Biological Chemistry 280 (6), 5054-5060, 2005 | 73 | 2005 |
Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate TY Li, L Song, Y Sun, J Li, C Yi, SM Lam, D Xu, L Zhou, X Li, Y Yang, ... Nature communications 9 (1), 1916, 2018 | 58 | 2018 |
A β-catenin-independent dorsalization pathway activated by Axin/JNK signaling and antagonized by Aida Y Rui, Z Xu, B Xiong, Y Cao, S Lin, M Zhang, SC Chan, W Luo, Y Han, ... Developmental cell 13 (2), 268-282, 2007 | 55 | 2007 |
RHOBTB3 promotes proteasomal degradation of HIFα through facilitating hydroxylation and suppresses the Warburg effect CS Zhang, Q Liu, M Li, SY Lin, Y Peng, D Wu, TY Li, Q Fu, W Jia, X Wang, ... Cell Research 25 (9), 1025-1042, 2015 | 52 | 2015 |