Folgen
Apirat Chaikuad
Apirat Chaikuad
Zugehörigkeit unbekannt
Bestätigte E-Mail-Adresse bei pharmchem.uni-frankfurt.de
Titel
Zitiert von
Zitiert von
Jahr
Copper is required for oncogenic BRAF signalling and tumorigenesis
DC Brady, MS Crowe, ML Turski, GA Hobbs, X Yao, A Chaikuad, S Knapp, ...
Nature 509 (7501), 492-496, 2014
5022014
Structural basis for Cul3 protein assembly with the BTB-Kelch family of E3 ubiquitin ligases
P Canning, CDO Cooper, T Krojer, JW Murray, ACW Pike, A Chaikuad, ...
Journal of Biological Chemistry 288 (11), 7803-7814, 2013
2912013
The ins and outs of selective kinase inhibitor development
S Müller, A Chaikuad, NS Gray, S Knapp
Nature chemical biology 11 (11), 818-821, 2015
2732015
A new class of small molecule inhibitor of BMP signaling
CE Sanvitale, G Kerr, A Chaikuad, MC Ramel, AH Mohedas, S Reichert, ...
PloS one 8 (4), e62721, 2013
2342013
A unique inhibitor binding site in ERK1/2 is associated with slow binding kinetics
A Chaikuad, E MC Tacconi, J Zimmer, Y Liang, NS Gray, M Tarsounas, ...
Nature chemical biology 10 (10), 853-860, 2014
2082014
Structure of the bone morphogenetic protein receptor ALK2 and implications for fibrodysplasia ossificans progressiva
A Chaikuad, I Alfano, G Kerr, CE Sanvitale, JH Boergermann, JT Triffitt, ...
Journal of Biological Chemistry 287 (44), 36990-36998, 2012
1982012
The cysteinome of protein kinases as a target in drug development
A Chaikuad, P Koch, SA Laufer, S Knapp
Angewandte Chemie International Edition 57 (16), 4372-4385, 2018
1952018
Discovery and characterization of GSK2801, a selective chemical probe for the bromodomains BAZ2A and BAZ2B
P Chen, A Chaikuad, P Bamborough, M Bantscheff, C Bountra, C Chung, ...
Journal of medicinal chemistry 59 (4), 1410-1424, 2016
1572016
Mechanism and consequence of the autoactivation of p38α mitogen-activated protein kinase promoted by TAB1
GF De Nicola, ED Martin, A Chaikuad, R Bassi, J Clark, L Martino, ...
Nature structural & molecular biology 20 (10), 1182-1190, 2013
1262013
Structure enabled design of BAZ2-ICR, a chemical probe targeting the bromodomains of BAZ2A and BAZ2B
L Drouin, S McGrath, LR Vidler, A Chaikuad, O Monteiro, C Tallant, ...
Journal of medicinal chemistry 58 (5), 2553-2559, 2015
1182015
10-Iodo-11H-indolo[3,2-c]quinoline-6-carboxylic Acids Are Selective Inhibitors of DYRK1A
H Falke, A Chaikuad, A Becker, N Loaëc, O Lozach, S Abu Jhaisha, ...
Journal of medicinal chemistry 58 (7), 3131-3143, 2015
1152015
Selective JAK3 inhibitors with a covalent reversible binding mode targeting a new induced fit binding pocket
M Forster, A Chaikuad, SM Bauer, J Holstein, MB Robers, CR Corona, ...
Cell chemical biology 23 (11), 1335-1340, 2016
1042016
Targeting low-druggability bromodomains: fragment based screening and inhibitor design against the BAZ2B bromodomain
FM Ferguson, O Fedorov, A Chaikuad, M Philpott, JRC Muniz, I Felletar, ...
Journal of medicinal chemistry 56 (24), 10183-10187, 2013
1002013
Development of potent, selective SRPK1 inhibitors as potential topical therapeutics for neovascular eye disease
J Batson, HD Toop, C Redondo, R Babaei-Jadidi, A Chaikuad, ...
ACS chemical biology 12 (3), 825-832, 2017
982017
Structural basis of intracellular TGF-β signaling: receptors and smads
A Chaikuad, AN Bullock
Cold Spring Harbor perspectives in biology 8 (11), a022111, 2016
892016
Discovery of a PCAF bromodomain chemical probe
M Moustakim, PGK Clark, L Trulli, AL Fuentes de Arriba, MT Ehebauer, ...
Angewandte Chemie 129 (3), 845-849, 2017
862017
UDP-glucose dehydrogenase: structure and function of a potential drug target
S Egger, A Chaikuad, KL Kavanagh, U Oppermann, B Nidetzky
Biochemical Society Transactions 38 (5), 1378-1385, 2010
852010
Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells
Y Morozumi, F Boussouar, M Tan, A Chaikuad, M Jamshidikia, G Colak, ...
Journal of molecular cell biology 8 (4), 349-362, 2016
792016
Isoform-selective ATAD2 chemical probe with novel chemical structure and unusual mode of action
AE Fernández-Montalván, M Berger, B Kuropka, SJ Koo, V Badock, ...
ACS chemical biology 12 (11), 2730-2736, 2017
772017
Novel p38α MAP kinase inhibitors identified from yoctoReactor DNA-encoded small molecule library
LK Petersen, P Blakskjær, A Chaikuad, AB Christensen, J Dietvorst, ...
MedChemComm 7 (7), 1332-1339, 2016
762016
Das System kann den Vorgang jetzt nicht ausführen. Versuchen Sie es später erneut.
Artikel 1–20