ian adcock
ian adcock
Bestätigte E-Mail-Adresse bei imperial.ac.uk
Titel
Zitiert von
Zitiert von
Jahr
International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma
KF Chung, SE Wenzel, JL Brozek, A Bush, M Castro, PJ Sterk, IM Adcock, ...
European respiratory journal 43 (2), 343-373, 2014
27652014
International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma
KF Chung, SE Wenzel, JL Brozek, A Bush, M Castro, PJ Sterk, IM Adcock, ...
European respiratory journal 43 (2), 343-373, 2014
27612014
Decreased histone deacetylase activity in chronic obstructive pulmonary disease
K Ito, M Ito, WM Elliott, B Cosio, G Caramori, OM Kon, A Barczyk, ...
New England Journal of Medicine 352 (19), 1967-1976, 2005
11012005
Glucocorticoid resistance in inflammatory diseases
PJ Barnes, IM Adcock
The Lancet 373 (9678), 1905-1917, 2009
10062009
Anti-inflammatory actions of steroids: molecular mechanisms
PJ Barnes, I Adcock, M Spedding, PM Vanhoutte
Trends in pharmacological sciences 14 (12), 436-441, 1993
9911993
Oxidative stress and redox regulation of lung inflammation in COPD
I Rahman, IM Adcock
European respiratory journal 28 (1), 219-242, 2006
9682006
Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1β-induced histone H4 acetylation on lysines 8 and 12
K Ito, PJ Barnes, IM Adcock
Molecular and cellular biology 20 (18), 6891-6903, 2000
8962000
How corticosteroids control inflammation: quintiles prize lecture 2005
PJ Barnes
British journal of pharmacology 148 (3), 245-254, 2006
7922006
Histone deacetylase 2–mediated deacetylation of the glucocorticoid receptor enables NF-κB suppression
K Ito, S Yamamura, S Essilfie-Quaye, B Cosio, M Ito, PJ Barnes, ...
The Journal of experimental medicine 203 (1), 7-13, 2006
7132006
Multifaceted mechanisms in COPD: inflammation, immunity, and tissue repair and destruction
KF Chung, IM Adcock
European Respiratory Journal 31 (6), 1334-1356, 2008
6422008
Histone acetylation and deacetylation: importance in inflammatory lung diseases
PJ Barnes, IM Adcock, K Ito
European Respiratory Journal 25 (3), 552-563, 2005
6422005
A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression
K Ito, S Lim, G Caramori, B Cosio, KF Chung, IM Adcock, PJ Barnes
Proceedings of the National Academy of Sciences 99 (13), 8921-8926, 2002
6142002
Cigarette smoking reduces histone deacetylase 2 expression, enhances cytokine expression, and inhibits glucocorticoid actions in alveolar macrophages
K Ito, S Lim, G Caramori, KF Chung, PJ Barnes, IM Adcock
The FASEB Journal 15 (6), 1110-1112, 2001
5912001
Activation and localization of transcription factor, nuclear factor-κ B, in asthma
LA Hart, VL Krishnan, IM Adcock, PJ Barnes, KF Chung
American journal of respiratory and critical care medicine 158 (5), 1585-1592, 1998
5551998
Increased expression of nuclear factor-κB in bronchial biopsies from smokers and patients with COPD
A Di Stefano, G Caramori, T Oates, A Capelli, M Lusuardi, I Gnemmi, F Ioli, ...
European Respiratory Journal 20 (3), 556-563, 2002
5452002
Relationship between exhaled nitric oxide and mucosal eosinophilic inflammation in children with difficult asthma, after treatment with oral prednisolone
DNR PAYNE, IANM ADCOCK, NM WILSON, TIM Oates, M SCALLAN, ...
American journal of respiratory and critical care medicine 164 (8), 1376-1381, 2001
5372001
Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages
BG Cosio, L Tsaprouni, K Ito, E Jazrawi, IM Adcock, PJ Barnes
The Journal of experimental medicine 200 (5), 689-695, 2004
5282004
Update on glucocorticoid action and resistance
K Ito, KF Chung, IM Adcock
Journal of Allergy and Clinical Immunology 117 (3), 522-543, 2006
5082006
p38 Mitogen-activated protein kinase–induced glucocorticoid receptor phosphorylation reduces its activity: Role in steroid-insensitive asthma
E Irusen, JG Matthews, A Takahashi, PJ Barnes, KF Chung, IM Adcock
Journal of Allergy and Clinical Immunology 109 (4), 649-657, 2002
4992002
Trichostatin A is a histone deacetylase inhibitor with potent antitumor activity against breast cancer in vivo
DM Vigushin, S Ali, PE Pace, N Mirsaidi, K Ito, I Adcock, RC Coombes
Clinical Cancer Research 7 (4), 971-976, 2001
4922001
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