Doxorubicin-induced necrosis is mediated by poly-(ADP-ribose) polymerase 1 (PARP1) but is independent of p53 HJ Shin, HK Kwon, JH Lee, X Gui, A Achek, JH Kim, S Choi Scientific reports 5 (1), 15798, 2015 | 122 | 2015 |
Doxorubicin induces cytotoxicity through upregulation of perk–dependent ATF3 EJ Park, HK Kwon, YM Choi, HJ Shin, S Choi Public Library of Science 7 (9), e44990, 2012 | 103 | 2012 |
Activating transcription factor 3 represses inflammatory responses by binding to the p65 subunit of NF-κB JW Kwon, HK Kwon, HJ Shin, YM Choi, MA Anwar, S Choi Scientific reports 5 (1), 14470, 2015 | 76 | 2015 |
Etoposide induced cytotoxicity mediated by ROS and ERK in human kidney proximal tubule cells HJ Shin, HK Kwon, JH Lee, MA Anwar, S Choi Scientific reports 6 (1), 1-13, 2016 | 70 | 2016 |
TLR4/MD2 specific peptides stalled in vivo LPS-induced immune exacerbation S Park, HJ Shin, M Shah, HY Cho, MA Anwar, A Achek, HK Kwon, B Lee, ... Biomaterials 126, 49-60, 2017 | 47 | 2017 |
Structural and functional analysis of cell adhesion and nuclear envelope nano-topography in cell death HK Kwon, JH Lee, HJ Shin, JH Kim, S Choi Scientific reports 5 (1), 15623, 2015 | 36 | 2015 |
Chitinase 3-like-1 is a therapeutic target that mediates the effects of aging in COVID-19 S Kamle, B Ma, CH He, B Akosman, Y Zhou, CM Lee, WS El-Deiry, ... JCI insight 6 (21), 2021 | 31 | 2021 |
Linear and rationally designed stapled peptides abrogate TLR4 pathway and relieve inflammatory symptoms in rheumatoid arthritis rat model A Achek, M Shah, JY Seo, HK Kwon, X Gui, HJ Shin, EY Cho, BS Lee, ... Journal of medicinal chemistry 62 (14), 6495-6511, 2019 | 31 | 2019 |
A cell-penetrating peptide blocks Toll-like receptor-mediated downstream signaling and ameliorates autoimmune and inflammatory diseases in mice HK Kwon, MC Patra, HJ Shin, X Gui, A Achek, S Panneerselvam, DJ Kim, ... Experimental & Molecular Medicine 51 (4), 1-19, 2019 | 29 | 2019 |
Etoposide induces necrosis through p53-mediated antiapoptosis in human kidney proximal tubule cells HK Kwon, HJ Shin, JH Lee, SH Park, MC Kwon, S Panneerselvam, ... Toxicological Sciences 148 (1), 204-219, 2015 | 23 | 2015 |
Toll‐like receptor 2 antagonists identified through virtual screening and experimental validation P Durai, HJ Shin, A Achek, HK Kwon, RG Govindaraj, S Panneerselvam, ... The FEBS journal 284 (14), 2264-2283, 2017 | 19 | 2017 |
PINK1 inhibits multimeric aggregation and signaling of MAVS and MAVS-dependent lung pathology SH Kim, HJ Shin, CM Yoon, SW Lee, L Sharma, CS Dela Cruz, MJ Kang American Journal of Respiratory Cell and Molecular Biology 64 (5), 592-603, 2021 | 11 | 2021 |
A novel small-molecule inhibitor of endosomal TLRs reduces inflammation and alleviates autoimmune disease symptoms in murine models MC Patra, A Achek, GY Kim, S Panneerselvam, HJ Shin, WY Baek, ... Cells 9 (7), 1648, 2020 | 11 | 2020 |
Distinct roles of type I and type III interferons during a native murine β coronavirus lung infection L Sharma, X Peng, H Qing, BK Hilliard, J Kim, A Swaminathan, J Tian, ... Journal of virology 96 (2), e01241-21, 2022 | 10 | 2022 |
Nucleotide‐binding domain and leucine‐rich‐repeat‐containing protein X1 deficiency induces nicotinamide adenine dinucleotide decline, mechanistic target of rapamycin activation … HJ Shin, SH Kim, HJ Park, MS Shin, I Kang, MJ Kang Aging cell 20 (7), e13410, 2021 | 10 | 2021 |
Mitochondrial antiviral signaling protein is crucial for the development of pulmonary fibrosis SH Kim, JY Lee, CM Yoon, HJ Shin, SW Lee, I Rosas, E Herzog, ... European Respiratory Journal 57 (4), 2021 | 10 | 2021 |
Coronavirus lung infection impairs host immunity against secondary bacterial infection by promoting lysosomal dysfunction X Peng, J Kim, G Gupta, K Agaronyan, MC Mankowski, A Korde, ... The Journal of Immunology 209 (7), 1314-1322, 2022 | 8 | 2022 |
Quasi-stem cells derived from human somatic cells by chemically modified carbon nanotubes JH Lee, HK Kwon, HJ Shin, GH Nam, JH Kim, S Choi ACS applied materials & interfaces 10 (10), 8417-8425, 2017 | 4 | 2017 |
VISTA (PD-1H) Is a Crucial Immune Regulator to Limit Pulmonary Fibrosis SH Kim, TS Adams, Q Hu, HJ Shin, G Chae, SE Lee, L Sharma, HK Kwon, ... American Journal of Respiratory Cell and Molecular Biology 69 (1), 22-33, 2023 | 3 | 2023 |
Epidermal growth factor receptor inhibition is protective in hyperoxia-induced lung injury ZM Harris, Y Sun, J Joerns, B Clark, B Hu, A Korde, L Sharma, HJ Shin, ... Oxidative Medicine and Cellular Longevity 2022, 2022 | 1 | 2022 |