Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity F Weinberg, R Hamanaka, WW Wheaton, S Weinberg, J Joseph, M Lopez, ... Proceedings of the National Academy of Sciences 107 (19), 8788-8793, 2010 | 1788 | 2010 |
Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis WW Wheaton, SE Weinberg, RB Hamanaka, S Soberanes, LB Sullivan, ... elife 3, e02242, 2014 | 1116 | 2014 |
Single-cell transcriptomic analysis of human lung provides insights into the pathobiology of pulmonary fibrosis PA Reyfman, JM Walter, N Joshi, KR Anekalla, AC McQuattie-Pimentel, ... American journal of respiratory and critical care medicine 199 (12), 1517-1536, 2019 | 1008 | 2019 |
Flow cytometric analysis of macrophages and dendritic cell subsets in the mouse lung AV Misharin, L Morales-Nebreda, GM Mutlu, GRS Budinger, H Perlman American journal of respiratory cell and molecular biology 49 (4), 503-510, 2013 | 900 | 2013 |
Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span AV Misharin, L Morales-Nebreda, PA Reyfman, CM Cuda, JM Walter, ... Journal of Experimental Medicine 214 (8), 2387-2404, 2017 | 872 | 2017 |
Minimizing oxidation and stable nanoscale dispersion improves the biocompatibility of graphene in the lung MC Duch, GRS Budinger, YT Liang, S Soberanes, D Urich, SE Chiarella, ... Nano letters 11 (12), 5201-5207, 2011 | 588 | 2011 |
Particulate matter air pollution: effects on the cardiovascular system RB Hamanaka, GM Mutlu Frontiers in endocrinology 9, 412302, 2018 | 522 | 2018 |
GI complications in patients receiving mechanical ventilation EA Mutlu, P Factor Chest 119 (4), 1222-1241, 2001 | 516 | 2001 |
Collection and analysis of exhaled breath condensate in humans GM Mutlu, KW Garey, RA Robbins, LH Danziger, I Rubinstein American journal of respiratory and critical care medicine 164 (5), 731-737, 2001 | 466 | 2001 |
Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio BM Emerling, F Weinberg, C Snyder, Z Burgess, GM Mutlu, B Viollet, ... Free Radical Biology and Medicine 46 (10), 1386-1391, 2009 | 375 | 2009 |
Mitochondrial reactive oxygen species regulate transforming growth factor-β signaling M Jain, S Rivera, EA Monclus, L Synenki, A Zirk, J Eisenbart, ... Journal of Biological Chemistry 288 (2), 770-777, 2013 | 360 | 2013 |
Ambient particulate matter accelerates coagulation via an IL-6–dependent pathway GM Mutlu, D Green, A Bellmeyer, CM Baker, Z Burgess, N Rajamannan, ... The Journal of clinical investigation 117 (10), 2952-2961, 2007 | 333 | 2007 |
Nonclassical Ly6C− monocytes drive the development of inflammatory arthritis in mice AV Misharin, CM Cuda, R Saber, JD Turner, AK Gierut, GK Haines, ... Cell reports 9 (2), 591-604, 2014 | 310 | 2014 |
Toll-like receptor 4 signaling augments transforming growth factor-β responses: a novel mechanism for maintaining and amplifying fibrosis in scleroderma S Bhattacharyya, K Kelley, DS Melichian, Z Tamaki, F Fang, Y Su, G Feng, ... The American journal of pathology 182 (1), 192-205, 2013 | 285 | 2013 |
Role of vasopressin in the management of septic shock GM Mutlu, P Factor Intensive care medicine 30 (7), 1276-1291, 2004 | 244 | 2004 |
Biocompatible nanoscale dispersion of single-walled carbon nanotubes minimizes in vivo pulmonary toxicity GM Mutlu, GRS Budinger, AA Green, D Urich, S Soberanes, SE Chiarella, ... Nano letters 10 (5), 1664-1670, 2010 | 242 | 2010 |
Mechanisms of pulmonary edema clearance GM Mutlu, JI Sznajder American Journal of Physiology-Lung Cellular and Molecular Physiology 289 (5 …, 2005 | 227 | 2005 |
Inhalational exposure to particulate matter air pollution alters the composition of the gut microbiome EA Mutlu, IY Comba, T Cho, PA Engen, C Yazıcı, S Soberanes, ... Environmental pollution 240, 817-830, 2018 | 208 | 2018 |
IL-6 inhibition in critically ill COVID-19 patients is associated with increased secondary infections LM Kimmig, D Wu, M Gold, NN Pettit, D Pitrak, J Mueller, AN Husain, ... Frontiers in medicine 7, 583897, 2020 | 201 | 2020 |
Particulate matter air pollution causes oxidant-mediated increase in gut permeability in mice EA Mutlu, PA Engen, S Soberanes, D Urich, CB Forsyth, R Nigdelioglu, ... Particle and fibre toxicology 8, 1-13, 2011 | 199 | 2011 |