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Nick Holford
Nick Holford
Professor Emeritus Clinical Pharmacology, University of Auckland
Verified email at auckland.ac.nz - Homepage
Title
Cited by
Cited by
Year
Understanding the dose-effect relationship: clinical application of pharmacokinetic-pharmacodynamic models
NH Holford, LB Sheiner
Clinical Pharmacokinetics 6 (6), 429-53, 1981
15101981
Mechanism-based concepts of size and maturity in pharmacokinetics
BJ Anderson, NHG Holford
Annu. Rev. Pharmacol. Toxicol. 48, 303-332, 2008
11242008
Mechanistic basis of using body size and maturation to predict clearance in humans
BJ Anderson, NHG Holford
Drug metabolism and pharmacokinetics 24 (1), 25-36, 2009
5262009
Human renal function maturation: a quantitative description using weight and postmenstrual age
MM Rhodin, BJ Anderson, AM Peters, MG Coulthard, B Wilkins, M Cole, ...
Pediatric nephrology 24, 67-76, 2009
4872009
A pharmacokinetic standard for babies and adults
N Holford, YA Heo, B Anderson
Journal of pharmaceutical sciences 102 (9), 2941-2952, 2013
3562013
Phase 1 clinical results with tandutinib (MLN518), a novel FLT3 antagonist, in patients with acute myelogenous leukemia or high-risk myelodysplastic syndrome: safety …
DJ DeAngelo, RM Stone, ML Heaney, SD Nimer, RL Paquette, ...
Blood 108 (12), 3674-3681, 2006
3122006
Model evaluation of continuous data pharmacometric models: metrics and graphics
THT Nguyen, MS Mouksassi, N Holford, N Al‐Huniti, I Freedman, ...
CPT: pharmacometrics & systems pharmacology 6 (2), 87-109, 2017
2942017
The visual predictive check—superiority to standard diagnostic (Rorschach) plots
N Holford
Abstr 738, 14, 2005
2542005
Clinical trial simulation: a review
N Holford, SC Ma, BA Ploeger
Clinical Pharmacology & Therapeutics 88 (2), 166-182, 2010
2202010
Influence of obesity on propofol pharmacokinetics: derivation of a pharmacokinetic model
LI Cortinez, BJ Anderson, A Penna, L Olivares, HR Munoz, NHG Holford, ...
British journal of anaesthesia 105 (4), 448-456, 2010
2142010
A tutorial on visual predictive checks
MO Karlsson, N Holford
abstr 1434, 17, 2008
2032008
Drug treatment effects on disease progression
PLS Chan, NHG Holford
Annual review of pharmacology and toxicology 41 (1), 625-659, 2001
1972001
Understanding dosing: children are small adults, neonates are immature children
BJ Anderson, NHG Holford
Archives of disease in childhood 98 (9), 737-744, 2013
1962013
A review of mixed‐effects models of tumor growth and effects of anticancer drug treatment used in population analysis
B Ribba, NH Holford, P Magni, I Trocóniz, I Gueorguieva, P Girard, C Sarr, ...
CPT: pharmacometrics & systems pharmacology 3 (5), 1-10, 2014
1922014
Morphine pharmacokinetics and pharmacodynamics in preterm and term neonates: secondary results from the NEOPAIN trial
KJS Anand, BJ Anderson, NHG Holford, RW Hall, T Young, B Shephard, ...
British journal of anaesthesia 101 (5), 680-689, 2008
1812008
Tips and traps analyzing pediatric PK data
BJ Anderson, NHG Holford
Pediatric Anesthesia 21 (3), 222-237, 2011
1762011
Negligible excretion of unchanged ketoprofen, naproxen, and probenecid in urine
RA Upton, JN Buskin, RL Williams, NHG Holford, S Riegelman
Journal of pharmaceutical sciences 69 (11), 1254-1257, 1980
1501980
Paracetamol plasma and cerebrospinal fluid pharmacokinetics in children
BJ Anderson, NHG Holford, GA Woollard, PLS Chan
British journal of clinical pharmacology 46 (3), 237-243, 1998
1371998
Importance of hematocrit for a tacrolimus target concentration strategy
E Størset, N Holford, K Midtvedt, S Bremer, S Bergan, A Åsberg
European journal of clinical pharmacology 70, 65-77, 2014
1252014
Rectal paracetamol dosing regimens: determination by computer simulation
BJ Anderson, NHG Holford
Pediatric Anesthesia 7 (6), 451-455, 1997
1201997
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