EGCG binds intrinsically disordered N-terminal domain of p53 and disrupts p53-MDM2 interaction J Zhao, A Blayney, X Liu, L Gandy, W Jin, L Yan, JH Ha, AJ Canning, ... Nature communications 12 (1), 986, 2021 | 159 | 2021 |
ALS-linked mutations affect UBQLN2 oligomerization and phase separation in a position-and amino acid-dependent manner TP Dao, B Martyniak, AJ Canning, Y Lei, EG Colicino, MS Cosgrove, ... Structure 27 (6), 937-951. e5, 2019 | 84 | 2019 |
Structure analysis suggests Ess1 isomerizes the carboxy-terminal domain of RNA polymerase II via a bivalent anchoring mechanism KEW Namitz, T Zheng, AJ Canning, NL Alicea-Velazquez, CA Castañeda, ... Communications Biology 4 (1), 398, 2021 | 9 | 2021 |
Kinetics of the multitasking high-affinity Win binding site of WDR5 in restricted and unrestricted conditions A Imran, BS Moyer, AJ Canning, D Kalina, TM Duncan, KJ Moody, ... Biochemical Journal 478 (11), 2145-2161, 2021 | 7 | 2021 |
Molecular determinants of the interaction between HSV-1 glycoprotein D and heparan sulfate LA Gandy, AJ Canning, H Lou, K Xia, P He, G Su, T Cairns, J Liu, F Zhang, ... Frontiers in Molecular Biosciences 9, 1043713, 2022 | 5 | 2022 |
Identification of proteins using four methods of matrix-assisted laser desorption ionization time-of-flight mass spectrometry KG Bendinskas, AJ Canning, AE Smith Journal of Chemical Education 96 (11), 2600-2605, 2019 | 4 | 2019 |
Parallel functional annotation of cancer-associated missense mutations in histone methyltransferases AJ Canning, S Viggiano, ME Fernandez-Zapico, MS Cosgrove Scientific reports 12 (1), 18487, 2022 | 2 | 2022 |
Hernia and hydrocele in boys DA Canning, C Pavlock Atlas of the Urologic Clinics of North America 12 (1), 1-13, 2004 | 1 | 2004 |
Parallel functional annotation of cancer-associated missense mutations in histone methyltransferases M Cosgrove, A Canning, S Viggiano, M Fernandez-Zapico | | 2022 |
Exploring the kinetics of the Win-site of WDR5 A Imran, BS Moyer, A Canning, D Kalina, T Duncan, KJ Moody, A Wolfe, ... Biophysical Journal 121 (3), 54a, 2022 | | 2022 |
A Structure/Function Perspective of Mixed Lineage Leukemia 3 (MLL3) Histone Monomethyltransferase Complexes and Their Cancer-Associated Catalytic Abnormalities AJ Canning State University of New York, Upstate Medical University, 2022 | | 2022 |
Sensing Mixed Lineage Leukemia Win Motif Peptide-WD Repeat Protein-5 Association with an Engineered Biosensor LA Mayse, A Canning, A Imran, M Cosgrove, L Movileanu Biophysical Journal 118 (3), 152a-153a, 2020 | | 2020 |
Solution Structure Studies of Ess1 Interactions with the RNAPII CTD Suggest a Dual Binding Mechanism that Differs from that of Human Pin1 T Zheng, K Namitz, A Canning, N Alicea-Velazquez, CA Castaneda, ... Biophysical Journal 118 (3), 531a, 2020 | | 2020 |
Disease-Linked Mutations in UBQLN2 Proline-Rich Region Promote Phase Separation and Liquid-To-Solid Phase Transitions CA Castaneda, TP Dao, B Martyniak, Y Lei, A Canning, E Colicino, ... Biophysical Journal 116 (3), 348a, 2019 | | 2019 |
Systematic Mutational Analysis of Mixed Lineage Leukemia 3 (MLL3) Histone Methyltransferase Active Site Suggests Single Phe/Tyr Switch Position to Regulate Product Specificity A Canning, N Alicea‐Velazquez, M Cosgrove The FASEB Journal 31, 755.4-755.4, 2017 | | 2017 |