| Immunoglobulin class-switch DNA recombination: induction, targeting and beyond Z Xu, H Zan, EJ Pone, T Mai, P Casali Nature Reviews Immunology 12 (7), 517-531, 2012 | 588 | 2012 |
| Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus W Yang, N Shen, DQ Ye, Q Liu, Y Zhang, XX Qian, N Hirankarn, D Ying, ... PLoS genetics 6 (2), e1000841, 2010 | 458 | 2010 |
| BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-κB pathway EJ Pone, J Zhang, T Mai, CA White, G Li, JK Sakakura, PJ Patel, ... Nature communications 3 (1), 767, 2012 | 315 | 2012 |
| CD40 ligand and appropriate cytokines induce switching to IgG, IgA, and IgE and coordinated germinal center and plasmacytoid phenotypic differentiation in a human monoclonal … A Cerutti, H Zan, A Schaffer, L Bergsagel, N Harindranath, EE Max, ... The Journal of Immunology 160 (5), 2145-2157, 1998 | 269 | 1998 |
| The translesion DNA polymerase ζ plays a major role in Ig and bcl-6 somatic hypermutation H Zan, A Komori, Z Li, A Cerutti, A Schaffer, MF Flajnik, M Diaz, P Casali Immunity 14 (5), 643-653, 2001 | 252 | 2001 |
| CD40 engagement triggers switching to IgA1 and IgA2 in human B cells through induction of endogenous TGF-β: evidence for TGF-β but not IL-10-dependent direct Sμ→ Sα and … H Zan, A Cerutti, P Dramitinos, A Schaffer, P Casali The Journal of Immunology 161 (10), 5217-5225, 1998 | 231 | 1998 |
| B cell-intrinsic epigenetic modulation of antibody responses by dietary fiber-derived short-chain fatty acids HN Sanchez, JB Moroney, H Gan, T Shen, JL Im, T Li, JR Taylor, H Zan, ... Nature communications 11 (1), 60, 2020 | 224 | 2020 |
| HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation SR Park, H Zan, Z Pal, J Zhang, A Al-Qahtani, EJ Pone, Z Xu, T Mai, ... Nature immunology 10 (5), 540-550, 2009 | 176 | 2009 |
| 14-3-3 adaptor proteins recruit AID to 5′-AGCT-3′–rich switch regions for class switch recombination Z Xu, Z Fulop, G Wu, EJ Pone, J Zhang, T Mai, LM Thomas, A Al-Qahtani, ... Nature structural & molecular biology 17 (9), 1124-1135, 2010 | 167 | 2010 |
| Toll-like receptors and B-cell receptors synergize to induce immunoglobulin class-switch DNA recombination: relevance to microbial antibody responses EJ Pone, H Zan, J Zhang, A Al-Qahtani, Z Xu, P Casali Critical Reviews™ in Immunology 30 (1), 2010 | 166 | 2010 |
| Regulation of Aicda expression and AID activity H Zan, P Casali Autoimmunity 46 (2), 83-101, 2013 | 161 | 2013 |
| Regulation of aicda Expression and AID Activity: Relevance to Somatic Hypermutation and Class Switch DNA Recombination Z Xu, EJ Pone, A Al-Qahtani, SR Park, H Zan, P Casali Critical Reviews™ in Immunology 27 (4), 2007 | 143 | 2007 |
| The translesion DNA polymerase θ plays a dominant role in immunoglobulin gene somatic hypermutation H Zan, N Shima, Z Xu, A Al‐Qahtani, AJ Evinger III, Y Zhong, ... The EMBO journal 24 (21), 3757-3769, 2005 | 141 | 2005 |
| Induction of Ig somatic hypermutation and class switching in a human monoclonal IgM+ IgD+ B cell line in vitro: definition of the requirements and modalities of hypermutation H Zan, A Cerutti, P Dramitinos, A Schaffer, Z Li, P Casali The Journal of Immunology 162 (6), 3437-3447, 1999 | 125 | 1999 |
| DNA repair in antibody somatic hypermutation P Casali, Z Pal, Z Xu, H Zan Trends in immunology 27 (7), 313-321, 2006 | 115 | 2006 |
| Chronic Lymphocytic Leukemia B Cells Can Undergo Somatic Hypermutation and Intraclonal Immunoglobulin VHDJH Gene Diversification C Gurrieri, P McGuire, H Zan, XJ Yan, A Cerutti, E Albesiano, SL Allen, ... The Journal of experimental medicine 196 (5), 629-639, 2002 | 115 | 2002 |
| Engagement of CD153 (CD30 ligand) by CD30+ T cells inhibits class switch DNA recombination and antibody production in human IgD+ IgM+ B cells A Cerutti, A Schaffer, RG Goodwin, S Shah, H Zan, S Ely, P Casali The Journal of Immunology 165 (2), 786-794, 2000 | 114 | 2000 |
| Histone deacetylase inhibitors upregulate B cell microRNAs that silence AID and Blimp-1 expression for epigenetic modulation of antibody and autoantibody responses CA White, EJ Pone, T Lam, C Tat, KL Hayama, G Li, H Zan, P Casali The Journal of Immunology 193 (12), 5933-5950, 2014 | 112 | 2014 |
| AID-dependent generation of resected double-strand DNA breaks and recruitment of Rad52/Rad51 in somatic hypermutation H Zan, X Wu, A Komori, WK Holloman, P Casali Immunity 18 (6), 727-738, 2003 | 104 | 2003 |
| Epigenetics of peripheral B-cell differentiation and the antibody response H Zan, P Casali Frontiers in immunology 6, 167217, 2015 | 99 | 2015 |
