| Anxiolytic-like properties of the anandamide transport inhibitor AM404 M Bortolato, P Campolongo, RA Mangieri, ML Scattoni, R Frau, V Trezza, ... Neuropsychopharmacology 31 (12), 2652-2659, 2006 | 255 | 2006 |
| Prenatal THC exposure produces a hyperdopaminergic phenotype rescued by pregnenolone R Frau, V Miczán, F Traccis, S Aroni, CI Pongor, P Saba, V Serra, ... Nature neuroscience 22 (12), 1975-1985, 2019 | 113 | 2019 |
| Steroid 5α-reductase as a novel therapeutic target for schizophrenia and other neuropsychiatric disorders S Paba, R Frau, S C Godar, P Devoto, F Marrosu, M Bortolato Current pharmaceutical design 17 (2), 151-167, 2011 | 104 | 2011 |
| PPARα regulates cholinergic-driven activity of midbrain dopamine neurons via a novel mechanism involving α7 nicotinic acetylcholine receptors M Melis, S Scheggi, G Carta, C Madeddu, S Lecca, A Luchicchi, ... Journal of Neuroscience 33 (14), 6203-6211, 2013 | 102 | 2013 |
| Antipsychotic-like properties of 5-α-reductase inhibitors M Bortolato, R Frau, M Orru, Y Bourov, F Marrosu, G Mereu, P Devoto, ... Neuropsychopharmacology 33 (13), 3146-3156, 2008 | 86 | 2008 |
| Maternal immune activation disrupts dopamine system in the offspring A Luchicchi, S Lecca, M Melis, M De Felice, F Cadeddu, R Frau, ... International Journal of Neuropsychopharmacology 19 (7), pyw007, 2016 | 83 | 2016 |
| Regional distribution of 5α-reductase type 2 in the adult rat brain: an immunohistochemical analysis MP Castelli, A Casti, A Casu, R Frau, M Bortolato, S Spiga, MG Ennas Psychoneuroendocrinology 38 (2), 281-293, 2013 | 80 | 2013 |
| Maladaptive defensive behaviours in monoamine oxidase A-deficient mice SC Godar, M Bortolato, R Frau, M Dousti, K Chen, JC Shih The international journal of neuropsychopharmacology/official scientific …, 2011 | 71 | 2011 |
| Cannabinoid self-administration attenuates PCP-induced schizophrenia-like symptoms in adult rats MS Spano, P Fadda, R Frau, L Fattore, W Fratta European Neuropsychopharmacology 20 (1), 25-36, 2010 | 67 | 2010 |
| NMDARs Mediate the Role of Monoamine Oxidase A in Pathological Aggression M Bortolato, SC Godar, M Melis, A Soggiu, P Roncada, A Casu, G Flore, ... Science Signalling 32 (25), 8574, 2012 | 63 | 2012 |
| Isolation rearing-induced reduction of brain 5 [alpha]-reductase expression: Relevance to dopaminergic impairments M Bortolato, P Devoto, P Roncada, R Frau, G Flore, P Saba, G Pistritto, ... Neuropharmacology, 2011 | 60 | 2011 |
| Inhibition of 5α-reductase in the nucleus accumbens counters sensorimotor gating deficits induced by dopaminergic activation P Devoto, R Frau, V Bini, G Pillolla, P Saba, G Flore, M Corona, F Marrosu, ... Psychoneuroendocrinology, 2011 | 55 | 2011 |
| The CB receptor agonist WIN 55,212-2 fails to elicit disruption of prepulse inhibition of the startle in Sprague-Dawley rats M Bortolato, GN Aru, R Frau, M Orru, GC Luckey, G Boi, GL Gessa Psychopharmacology 177 (3), 264-271, 2005 | 53 | 2005 |
| Activation of GABA B receptors reverses spontaneous gating deficits in juvenile DBA/2J mice M Bortolato, R Frau, M Orrù, AP Piras, M Fà, A Tuveri, M Puligheddu, ... Psychopharmacology 194 (3), 361-369, 2007 | 52 | 2007 |
| Sleep deprivation disrupts prepulse inhibition of the startle reflex: reversal by antipsychotic drugs R Frau, M Orrù, M Puligheddu, GL Gessa, G Mereu, F Marrosu, ... Int J Neuropsychopharmacol 11 (7), 947-55, 2008 | 50 | 2008 |
| Kappa opioid receptor activation disrupts prepulse inhibition of the acoustic startle in rats M Bortolato, GN Aru, R Frau, M Orrù, M Fà, M Manunta, M Puddu, ... Biological psychiatry 57 (12), 1550-1558, 2005 | 49 | 2005 |
| Baclofen reverses the reduction in prepulse inhibition of the acoustic startle response induced by dizocilpine, but not by apomorphine M Bortolato, R Frau, GN Aru, M Orru, GL Gessa Psychopharmacology 171 (3), 322-330, 2004 | 49 | 2004 |
| The neurosteroidogenic enzyme 5α-reductase modulates the role of D1 dopamine receptors in rat sensorimotor gating R Frau, LJ Mosher, V Bini, G Pillolla, R Pes, P Saba, S Fanni, P Devoto, ... Psychoneuroendocrinology 63, 59-67, 2016 | 46 | 2016 |
| Inhibition of 5α-reductase attenuates behavioral effects of D1-, but not D2-like receptor agonists in C57BL/6 mice R Frau, G Pillolla, V Bini, S Tambaro, P Devoto, M Bortolato Psychoneuroendocrinology 38 (4), 542-551, 2013 | 43 | 2013 |
| New vistas on cannabis use disorder M Melis, R Frau, PW Kalivas, S Spencer, V Chioma, E Zamberletti, ... Neuropharmacology 124, 62-72, 2017 | 39 | 2017 |
