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Pekka Tiikkainen
Pekka Tiikkainen
Bayer Pharmaceuticals
Bestätigte E-Mail-Adresse bei bayer.com
Titel
Zitiert von
Zitiert von
Jahr
Computational tools for polypharmacology and repurposing
J Achenbach, P Tiikkainen, L Franke, E Proschak
Future medicinal chemistry 3 (8), 961-968, 2011
892011
Estimating error rates in bioactivity databases
P Tiikkainen, L Bellis, Y Light, L Franke
Journal of chemical information and modeling 53 (10), 2499-2505, 2013
732013
Analysis of commercial and public bioactivity databases
P Tiikkainen, L Franke
Journal of chemical information and modeling 52 (2), 319-326, 2012
582012
Critical comparison of virtual screening methods against the MUV data set
P Tiikkainen, P Markt, G Wolber, J Kirchmair, S Distinto, A Poso, ...
Journal of chemical information and modeling 49 (10), 2168-2178, 2009
512009
Comparison of structure fingerprint and molecular interaction field based methods in explaining biological similarity of small molecules in cell-based screens
P Tiikkainen, A Poso, O Kallioniemi
Journal of computer-aided molecular design 23, 227-239, 2009
132009
Centmitor-1, a novel acridinyl-acetohydrazide, possesses similar molecular interaction field and antimitotic cellular phenotype as rigosertib, on 01910. Na
JHE Mäki-Jouppila, LJ Laine, J Rehnberg, E Narvi, P Tiikkainen, ...
Molecular cancer therapeutics 13 (5), 1054-1066, 2014
102014
Learning conditional variational autoencoders with missing covariates
S Ramchandran, G Tikhonov, O Lönnroth, P Tiikkainen, H Lähdesmäki
Pattern Recognition 147, 110113, 2024
72024
Distinct gene expression profiles in adult rat brains after acute MK-801 and cocaine treatments
M Storvik, P Tiikkainen, M van Iersel, G Wong
European neuropsychopharmacology 16 (3), 211-219, 2006
72006
Study of ligand-based virtual screening tools in computer-aided drug design
P Tiikkainen
Annales Universitatis Turkuensis D 897, 2010
52010
VTT-006, an anti-mitotic compound, binds to the Ndc80 complex and suppresses cancer cell growth in vitro
LJ Laine, JHE Mäki-Jouppila, E Kutvonen, P Tiikkainen, TKM Nyholm, ...
Oncoscience 8, 134, 2021
12021
Adverse event prediction using a task-specific generative model
O Lönnroth, S Ramchandran, P Tiikkainen, M Öğretir, J Leinonen, ...
ICML 3rd Workshop on Interpretable Machine Learning in Healthcare (IMLH), 2023
2023
VTT-006, a novel anti-mitotic compound, binds to the Ndc80 complex and suppresses cancer cell growth in vitro
L Laine, J Maki-Jouppila, E Kutvonen, P Tiikkainen, T Nyholm, J Tien, ...
MOLECULAR BIOLOGY OF THE CELL 25, 2014
2014
Treatment of L-DOPA-induced dyskinesia with OPC-14523 or OPC-34712
P Tiikkainen, L Franke
EP Patent 2,792,359, 2014
2014
Discovery of Novel Anti-Mitotic Compounds Targeting Hec1
L Laine, JH Maki-Jouppila, A Kukkonen-Macchi, T Nyholm, P Tiikkainen, ...
MOLECULAR BIOLOGY OF THE CELL 22, 2011
2011
High-throughput siRNA screening reveals candidate therapeutic targets for clinically aggressive breast cancers, including several genes in the HER-2 amplicon
K Kleivi, K Hellstrom, H Edgren, S Haapa-Paananen, M Wolf, S Pollari, ...
Cancer Research 68 (9_Supplement), 918-918, 2008
2008
A link between multiple high throughput technology datasets
E Bucher, P Kohonen, V Fey, J Mpindi, H Sara, T Pisto, H Edgren, ...
9th International Conference on Systems Biology, ICSB2008, 186, 2008
2008
High-throughput gene silencing in breast cancer by RNAi reveals functional taxonomies and identifies candidate drug targets overexpressed in highly proliferative clinical …
K Kleivi, S Haapa-Paananen, H Edgren, M Wolf, S Pollari, N Salhberg, ...
Cancer Research 67 (9_Supplement), 4955-4955, 2007
2007
RNA interference profiles, gene expression, and copy number changes in bone metastatic breast cancer cells: an integrated molecular and functional screening
S Pollari, M Perälä, S Haapa-Paananen, N Sahlberg, K Ojala, ...
Cancer Research 66 (8_Supplement), 978-978, 2006
2006
Structural/Ligand and Cell-based High-throughput Screens for Identification of Allosteric PLK1 Inhibitors
J Rehnberg, M Vuoriluoto, P Halonen, P Tiikkainen, N Sahlberg, M Perala, ...
MOLECULAR BIOLOGY OF THE CELL 17, 2006
2006
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