Jac Charlesworth

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John BlangeroProfessor of Human Genetics, School of Medicine, University of Texas Rio Grande ValleyVerified email at utrgv.edu
Eric K MosesUniversity of Tasmania, Menzies Institute for Medical ResearchVerified email at utas.edu.au
Ingrid van der MeiMenzies Institute for Medical Research, University of TasmaniaVerified email at utas.edu.au
Kathryn BurdonMenzies Institute for Medical Research, University of TasmaniaVerified email at utas.edu.au
Steve Simpson, Jr.MSRA Postdoctoral Reseach FellowVerified email at utas.edu.au
David A MackeyProfessor of Ophthalmology, University of Western AustraliaVerified email at lei.org.au
David C GlahnPsychiatry, Boston Children's Hospital and Harvard Medical SchoolVerified email at childrens.harvard.edu
Alex HewittUniversity of TasmaniaVerified email at utas.edu.au
Peter KochunovProfessor, Department of Psychiatry and Behavioral Science, University of Texas Health ScienceVerified email at uth.tmc.edu
Dr Rodney A Lea (PhD)Queensland University of TechnologyVerified email at qut.edu.au
Peter T. FoxResearch Imaging Institute, University of Texas Health Science Center at San AntonioVerified email at uthscsa.edu
Michele SaleAssociate Professor of Public Health Sciences, University of VirginiaVerified email at virginia.edu
Anderson M. WinklerUniversity of Texas Rio Grande ValleyVerified email at utrgv.edu
Melanie BahloTheme Leader, Healthy Development and Ageing, The Walter and Eliza Hall Institute ofVerified email at wehi.edu.au
Stuart MacGregorProfessor, Statistical Genetics, QIMR Berghofer Medical Research Institute, Brisbane, AustraliaVerified email at qimr.edu.au
Judith FieldResearch Scientist, CSL Ltd.Verified email at csl.com.au
Liesel M FitzGeraldSenior Research Fellow, Menzies Institute for Medical ResearchVerified email at utas.edu.au
Emma SprootenDonders Institute for Brain, Cognition and BehaviourVerified email at mssm.edu
Sharon R. BrowningResearch Professor of Biostatistics, University of WashingtonVerified email at uw.edu
John FingertProfessor of Ophthalmology, Carver College of Medicine, University of IowaVerified email at uiowa.edu

Jac Charlesworth

Menzies Institute for Medical Research

Verified email at utas.edu.au - Homepage

Statistical genetics genetics bioinformatics systems biology multiple sclerosis


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Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility International Multiple Sclerosis Genetics Consortium*†, ANZgene, ... Science 365 (6460), eaav7188, 2019	837	2019
Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes HHH Göring, JE Curran, MP Johnson, TD Dyer, J Charlesworth, SA Cole, ... Nature genetics 39 (10), 1208-1216, 2007	628	2007
High dimensional endophenotype ranking in the search for major depression risk genes DC Glahn, JE Curran, AM Winkler, MA Carless, JW Kent Jr, ... Biological psychiatry 71 (1), 6-14, 2012	198	2012
Genetic Analysis Workshop 17 mini-exome simulation L Almasy, TD Dyer, JM Peralta, JW Kent, JC Charlesworth, JE Curran, ... BMC proceedings 5, 1-9, 2011	189	2011
Transcriptomic epidemiology of smoking: the effect of smoking on gene expression in lymphocytes JC Charlesworth, JE Curran, MP Johnson, HHH Göring, TD Dyer, ... BMC medical genomics 3, 1-11, 2010	142	2010
Low-frequency and rare-coding variation contributes to multiple sclerosis risk M Mitrovič, NA Patsopoulos, AH Beecham, T Dankowski, A Goris, ... Cell 175 (6), 1679-1687. e7, 2018	135	2018
The path to open-angle glaucoma gene discovery: endophenotypic status of intraocular pressure, cup-to-disc ratio, and central corneal thickness J Charlesworth, PL Kramer, T Dyer, V Diego, JR Samples, JE Craig, ... Investigative ophthalmology & visual science 51 (7), 3509-3514, 2010	133	2010
Apparent autosomal dominant keratoconus in a large Australian pedigree accounted for by digenic inheritance of two novel loci KP Burdon, DJ Coster, JC Charlesworth, RA Mills, KJ Laurie, C Giunta, ... Human genetics 124, 379-386, 2008	94	2008
Genetic association of preeclampsia to the inflammatory response gene SEPS1 EK Moses, MP Johnson, L Tømmerdal, S Forsmo, JE Curran, LJ Abraham, ... American journal of obstetrics and gynecology 198 (3), 336. e1-336. e5, 2008	93	2008
A Polymorphism in the HLA-DPB1 Gene Is Associated with Susceptibility to Multiple Sclerosis J Field, SR Browning, LJ Johnson, P Danoy, MD Varney, BD Tait, ... PloS one 5 (10), e13454, 2010	85	2010
Genetic basis of neurocognitive decline and reduced white-matter integrity in normal human brain aging DC Glahn, JW Kent Jr, E Sprooten, VP Diego, AM Winkler, JE Curran, ... Proceedings of the National Academy of Sciences 110 (47), 19006-19011, 2013	75	2013
A rare P2X7 variant Arg307Gln with absent pore formation function protects against neuroinflammation in multiple sclerosis BJ Gu, J Field, S Dutertre, A Ou, TJ Kilpatrick, J Lechner-Scott, R Scott, ... Human molecular genetics 24 (19), 5644-5654, 2015	70	2015
The genetics of multiple sclerosis R Lin, J Charlesworth, I van der Mei, BV Taylor Practical neurology 12 (5), 279-288, 2012	68	2012
An Immunochip-based interrogation of scleroderma susceptibility variants identifies a novel association at DNASE1L3 J Zochling, F Newell, JC Charlesworth, P Leo, J Stankovich, A Cortes, ... Arthritis research & therapy 16, 1-7, 2014	67	2014
Rediscovering the value of families for psychiatric genetics research DC Glahn, VL Nimgaonkar, H Raventós, J Contreras, AM McIntosh, ... Molecular psychiatry 24 (4), 523-535, 2019	64	2019
Heritability of central corneal thickness in nuclear families JA Landers, AW Hewitt, DP Dimasi, JC Charlesworth, T Straga, RAD Mills, ... Investigative ophthalmology & visual science 50 (9), 4087-4090, 2009	63	2009
Genetic loci for Epstein-Barr virus nuclear antigen-1 are associated with risk of multiple sclerosis Y Zhou, G Zhu, JC Charlesworth, S Simpson Jr, R Rubicz, HHH Göring, ... Multiple Sclerosis Journal 22 (13), 1655-1664, 2016	60	2016
Genetic determinants of mitochondrial content JE Curran, MP Johnson, TD Dyer, HHH Göring, JW Kent, ... Human molecular genetics 16 (12), 1504-1514, 2007	57	2007
Linkage to 10q22 for maximum intraocular pressure and 1p32 for maximum cup-to-disc ratio in an extended primary open-angle glaucoma pedigree JC Charlesworth, TD Dyer, JM Stankovich, J Blangero, DA Mackey, ... Investigative ophthalmology & visual science 46 (10), 3723-3729, 2005	57	2005
A genome-wide analysis of'Bounty'descendants implicates several novel variants in migraine susceptibility HC Cox, RA Lea, C Bellis, M Carless, TD Dyer, J Curran, J Charlesworth, ... Neurogenetics 13, 261-266, 2012	52	2012

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